Korrespondierender Autor

Daniel Kopetzki
Telefon:+49 30 838-59561Fax:+49 30 838-59302

Chemistry

Research report (imported) 2012 - Max Planck Institute of Colloids and Interfaces

Efficient continuous flow synthesis of the anti-malarial drug artemisinin

Authors

Kopetzki, Daniel

Departments

Biomolekulare Systeme (Prof. Dr. Peter H. Seeberger)

With nearly 1 million people dying per year, malaria is a global health problem. Artemisinin combination therapies are regarded as first-line drugs. However, their supply is limited, as artemisinin is currently solely extracted from plants. Its precursor dihydroartemisinic acid on the other hand can be obtained by a biotechnological process. A continuous flow chemistry setup was developed to produce artemisinin from this precursor in high yield just using oxygen and light.
 
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