Complex Systems • Microbiology

Research report (imported) 2011 - Max Planck Institute of Colloids and Interfaces

Design principles and economy of cellular information processing

Authors

Klumpp, Stefan

Departments

Theorie und Bio-Systeme (Prof. Dr. Reinhard Lipowsky)
Max-Planck-Institut für Kolloid- und Grenzflächenforschung

Natural and synthetic genetic circuits are always coupled to the physiological state of the cell in which they reside. For example, the concentrations of RNA polymerases and ribosomes that are available for the readout of the genetic information depend on the cellular growth rate. Theoretical studies can help to investigate the coupling of regulatory mechanisms and growth and to uncover principles that underlie the efficient use of molecular machines.
 
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