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Dr. Christoph Rademacher

Group Leader
Phone:+49 331 567-9358

Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam

Structural Glycobiology

Room: 0.176

Structural Glycobiology

Structural Glycobiology

The  Research Group “Structural Glycobiology” has a strong focus on protein-ligand interactions using biophysical and computational techniques. In particular, we are interested in glycan-binding proteins, developing small molecular inhibitors as well as studying the recognition of their natural carbohydrate ligands. These findings are combined with functional studies of glycan-binding proteins in their native environment to foster our understanding of glycobiology in a structural context.

Research

The  Research Group “Structural Glycobiology” has a strong focus on protein-ligand interactions using biophysical and computational techniques. In particular, we are interested in glycan-binding proteins, developing small molecular inhibitors as well as studying the recognition of their natural carbohydrate ligands. These findings are combined with functional studies of glycan-binding proteins in their native environment to foster our understanding of glycobiology in a structural context. [more]
<div id="main_content_3_block" class="edit_text_block" title="Absatz bearbeiten" data-attr="main_content" data-block="main_content_3_block" data-id="38314">Dr. Christoph Rademacher, Jonas Aretz, Jonas Hanske, Eike Wamhoff, Jessica Schulze, Hannes Baukmann, Henrik Schmidt, Elena Shanina, Lennart Schnirch, Stefanie Irmer-Stooff</div>

Group Members

Dr. Christoph Rademacher, Jonas Aretz, Jonas Hanske, Eike Wamhoff, Jessica Schulze, Hannes Baukmann, Henrik Schmidt, Elena Shanina, Lennart Schnirch, Stefanie Irmer-Stooff
[more]
<ol class="list">
<li>Aretz J, Kondo Y, Honda K, Anumala UR, Nazaré M, Watanabe N, Osada H,  Rademacher C, Chemical fragment arrays for rapid druggability assessment. Chem Comm, 2016, accepted</li>
<li>Aretz J, Wratil PR, Wamhoff EC, Nguyen HG, Reutter W, Rademacher C, Fragment-screening of N-acetylmannosamine kinase reveals non-carbohydrate inhibitors. Can J Chem, 2016, accepted</li>
<li>Aretz J., Wamhoff E-C., Hanske J., Heymann D., Rademacher C., Computational and experimental prediction of human C-type lectin receptor druggability. Front. Immunol. 2014, 5, 323</li>
</ol>

Publications

  1. Aretz J, Kondo Y, Honda K, Anumala UR, Nazaré M, Watanabe N, Osada H,  Rademacher C, Chemical fragment arrays for rapid druggability assessment. Chem Comm, 2016, accepted
  2. Aretz J, Wratil PR, Wamhoff EC, Nguyen HG, Reutter W, Rademacher C, Fragment-screening of N-acetylmannosamine kinase reveals non-carbohydrate inhibitors. Can J Chem, 2016, accepted
  3. Aretz J., Wamhoff E-C., Hanske J., Heymann D., Rademacher C., Computational and experimental prediction of human C-type lectin receptor druggability. Front. Immunol. 2014, 5, 323
[more]
Drug Discovery Seminar<br />Glycobiology Lecture and Seminar

Teaching

Drug Discovery Seminar
Glycobiology Lecture and Seminar [more]
 
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