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Dr. Monika Rumpler
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Ludwig Boltzmann Institut für Osteologie
Hanusch-KH, Oav. III, UG
Heinrich- Collin-Straße 30 A-1140 Wien, Austria
phone: +43-(0)1-91021-86924
fax: +43-(0)1-91021-86929
email: monika.rumpler@osteologie.at
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| Academic Career: |
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1992 - 2000 |
Study of Microbiology at the University of Vienna |
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2000 |
Graduation Magistra rerum naturalis (M.S. in Biology)
Title of Master thesis:
"Isolation and characterization of differentially expressed mRNAs from subconfluent and confluent osteoblasts-like cell cultures" at the Ludwig Boltzmann Institute of Osteology, Vienna |
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2000 - 2004 |
PhD in Molecular Biology, University of Vienna, Dept. of Microbiology
Title of doctoral thesis:
"Isolation and characterization of differentially regulated mRNAs during the differentiation process of osteoblasts" at the Ludwig Boltzmann Institute of Osteology, Vienna |
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2004 - 2007 |
Post-doc at the Max-Planck Institute of Colloids and Interfaces, Department of Biomaterials, Germany |
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| Projects: |
| I started my work on the bone field in molecular biology where I worked with osteoblastic cell lines and primary isolated osteoblasts. The osteoblasts represent the cell population in the bone tissue, which forms the extracellular matrix. The mineralization of this collagenmatrix leads to the formation of bone tissue. These cells derive form bone marrow stromal cells and undergo a differentiation process from an immature (preosteoblastic) stage into highly differentiated and specialized (mature) osteoblasts. In addition to the physiological development, this process is influenced (accelerated or inhibited) by various hormones and the formation of cell-cell contacts, which are an important prerequisite for the whole differentiation process of osteoblasts in vitro. One aim of our interests is to study the exact influence of the environment on the developmental process of osteoblasts and how they behave under defined changed conditions. Another interest is focused on the combination of cell biology and physical methods, which provides a new tool to get a deeper insight what happens in a cell. Cells react on changes of the environmental conditions which results changes in their morphology. Scattering methods as well as spectroscopy are very powerful tools to observe and analyse these reactions on a quantitative and new hierarchical level. |
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selected publications
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| © 2012, Max-Planck-Institut für Kolloid- und Grenzflächenforschung, Potsdam |
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