Suchergebnisse

Zeitschriftenartikel (16)

1. 2019
   MPG.PuRe

   DOI

   publisher-version
   Zeitschriftenartikel

   Aretz, J.; Rademacher, C.: Ranking Hits From Saturation Transfer Difference Nuclear Magnetic Resonance–Based Fragment Screening. Frontiers in Chemistry 7, 215 (2019)
2. 2018
   MPG.PuRe

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   Zeitschriftenartikel

   Aretz, J.; Anumala, U. R.; Fuchsberger, F. F.; Molavi, N.; Ziebart, N.; Zhang, H.; Nazaré, M.; Rademacher, C.: Allosteric inhibition of a mammalian lectin. Journal of the American Chemical Society 140 (44), S. 14915 - 14925 (2018)
3. MPG.PuRe

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   Zeitschriftenartikel

   Ota, F.; Hirayama, T.; Kizuka, Y.; Yamaguchi, Y.; Fujinawa, R.; Nagata, M.; Ismanto, H. S.; Lepenies, B.; Aretz, J.; Rademacher, C. et al.; Seeberger, P. H.; Angata, T.; Kitazume, S.; Yoshida, K.; Betsuyaku, T.; Kida, K.; Yamasaki, S.; Taniguchi, N.: High affinity sugar ligands of C-type lectin receptor langerin. Biochimica et Biophysica Acta (BBA) - General Subjects 1862 (7), S. 1592 - 1601 (2018)
4. MPG.PuRe

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   Zeitschriftenartikel

   Schulze, J.; Baukmann, H.; Wawrzinek, R.; Fuchsberger, F. F.; Specker, E.; Aretz, J.; Nazaré, M.; Rademacher, C.: CellFy: A Cell-Based Fragment Screen against C-Type Lectins. ACS Chemical Biology 13 (12), S. 3229 - 3235 (2018)
5. 2017
   MPG.PuRe

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   Spiliotopoulos, D.; Zhu, J.; Wamhoff, E.-C.; Deerain, N.; Marchand, J.-R.; Aretz, J.; Rademacher, C.; Caflisch, A.: Virtual Screen to NMR (VS2NMR): Discovery of fragment hits for the CBP bromodomain. Bioorganic & Medicinal Chemistry Letters 27 (11), S. 2472 - 2478 (2017)
6. MPG.PuRe

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   Aretz, J.; Baukmann, H.; Shanina, E.; Hanske, J.; Wawrzinek, R.; Zapol'skii, V. A.; Seeberger, P. H.; Kaufmann, D. E.; Rademacher, C.: Identification of multiple druggable secondary sites by fragment screening against DC-SIGN. Angewandte Chemie International Edition 56 (25), S. 7292 - 7296 (2017)
7. MPG.PuRe

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   Aretz, J.; Baukmann, H.; Shanina, E.; Hanske, J.; Wawrzinek, R.; Zapol'skii, V. A.; Seeberger, P. H.; Kaufmann, D. E.; Rademacher, C.: Identifikation sekundärer Bindestellen auf DC-SIGN mithilfe eines Fragment-Screenings. Angewandte Chemie 129 (25), S. 7398 - 7402 (2017)
8. MPG.PuRe

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   Zeitschriftenartikel

   Gao, C.; Fujinawa, R.; Yoshida, T.; Ueno, M.; Ota, F.; Kizuka, Y.; Hirayama, T.; Korekane, H.; Kitazume, S.; Maeno, T. et al.; Ohtsubo, K.; Yoshida, K.; Yamaguchi, Y.; Lepenies, B.; Aretz, J.; Rademacher, C.; Kabata, H.; Hegab, A. E.; Seeberger, P. H.; Betsuyaku, T.; Kida, K.; Taniguchi, N.: A keratan sulfate disaccharide prevents inflammation and the progression of emphysema in murine models. American Journal of Physiology - Lung Cellular and Molecular Physiology 312 (2), S. L268 - L276 (2017)
9. MPG.PuRe

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   Zeitschriftenartikel

   Hanske, J.; Schulze, J.; Aretz, J.; McBride, R.; Loll, B.; Schmidt, H.; Knirel, Y.; Rabsch, W.; Wahl, M. C.; Paulson, J. C. et al.; Rademacher, C.: Bacterial Polysaccharide Specificity of the Pattern Recognition Receptor Langerin Is Highly Species-dependent. The Journal of Biological Chemistry 292 (3), S. 862 - 871 (2017)
10. 2016
    MPG.PuRe

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    supplementary-material
    Zeitschriftenartikel

    Wamhoff, E.-C.; Hanske, J.; Schnirch, L.; Aretz, J.; Grube, M.; Varón Silva, D.; Rademacher, C.: ¹⁹F NMR-Guided Design of Glycomimetic Langerin Ligands. ACS Chemical Biology 11 (9), S. 2407 - 2413 (2016)
11. MPG.PuRe

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    publisher-version

    supplementary-material
    Zeitschriftenartikel

    Aretz, J.; Kondoh, Y.; Honda, K.; Anumala, U. R.; Nazaré, M.; Watanabe, N.; Osada, H.; Rademacher, C.: Chemical fragment arrays for rapid druggability assessment. Chemical Communications 52 (58), S. 9067 - 9070 (2016)
12. MPG.PuRe

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    Zeitschriftenartikel

    Aretz, J.; Wratil, P. R.; Wamhoff, E.-C.; Nguyen, H. G.; Reutter, W.; Rademacher, C.: Fragment-screening of N-acetylmannosamine kinase reveals non-carbohydrate inhibitors. Canadian Journal of Chemistry 94 (11), S. 920 - 926 (2016)
13. 2015
    MPG.PuRe

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    Aretz, J.; Rademacher, C.: Fragmentbasierte Wirkstoffentwicklung. Nachrichten aus der Chemie 63 (2), S. 116 - 121 (2015)
14. 2014
    MPG.PuRe

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    Aretz, J.; Wamhoff, E.-C.; Hanske, J.; Heymann, D.; Rademacher, C.: Computational and experimental prediction of human C-type lectin receptor druggability. Frontiers in immunology, 5:323 (2014)
15. MPG.PuRe

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    Zeitschriftenartikel

    Bröcker, F.; Aretz, J.; Yang, Y.; Hanske, J.; Guo, X.; Reinhardt, A.; Wahlbrink, A.; Rademacher, C.; Anish, C.; Seeberger, P. H.: Epitope recognition of antibodies against a Yersinia pestis lipopolysaccharide trisaccharide component. ACS Chemical Biology 9 (4), S. 867 - 873 (2014)
16. MPG.PuRe

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    Zeitschriftenartikel

    Ponader, D.; Maffre, P.; Aretz, J.; Pussak, D.; Ninnemann, N. M.; Schmidt, S.; Seeberger, P. H.; Rademacher, C.; Nienhaus, G. U.; Hartmann, L.: Carbohydrate-lectin recognition of sequence-defined heteromultivalent glycooligomers. Journal of the American Chemical Society 136 (5), S. 2008 - 2016 (2014)

Meeting Abstract (1)

1. 2014
   MPG.PuRe
   Meeting Abstract

   Aretz, J.; Wamhoff, E.-C.; Hanske, J.; Heymann, D.; Rademacher, C.: Druggability of mammalian C-type lectin receptors. In Abstracts of Papers of the American Chemical Society, 248. 248th National Meeting of the American-Chemical-Society (ACS), San Francisco, CA, 10. August 2014 - 14. August 2014. (2014)

Hochschulschrift - Doktorarbeit (1)

1. 2016
   MPG.PuRe
   Hochschulschrift - Doktorarbeit

   Aretz, J.: Fragment-based Design of Novel Lectin Ligands. Dissertation, 251 S., Freie Universität Berlin, Berlin (2016)