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Zeitschriftenartikel (23)

  1. 2018
    Bröcker, F.; Götze, S.; Hudon, J.; Rathwell, D. C. K.; Pereira, C. L.; Stallforth, P.; Chakkumkal, A.; Seeberger, P. H.: Synthesis, Liposomal Formulation, and Immunological Evaluation of a Minimalistic Carbohydrate-α-GalCer Vaccine Candidate. Journal of Medicinal Chemistry 61 (11), S. 4918 - 4927 (2018)
  2. Schumann, B.; Reppe, K.; Kaplonek, P.; Wahlbrink, A.; Chakkumkal, A.; Witzenrath, M.; Pereira, C. L.; Seeberger, P. H.: Development of an Efficacious, Semisynthetic Glycoconjugate Vaccine Candidate against Streptococcus pneumoniae Serotype 1. ACS Central Science 4 (3), S. 357 - 361 (2018)
  3. 2017
    Schumann, B.; Hahm, H. S.; Parameswarappa, S. G.; Reppe, K.; Wahlbrink, A.; Govindan, S.; Kaplonek, P.; Pirofski, L.-a.; Witzenrath, M.; Chakkumkal, A. et al.; Pereira, C. L.; Seeberger, P. H.: A semisynthetic Streptococcus pneumoniae serotype 8 glycoconjugate vaccine. Science Translational Medicine 9 (380), eaaf5347 (2017)
  4. 2016
    Broecker, F.; Hanske, J.; Martin, C. E.; Baek, J. Y.; Wahlbrink, A.; Wojcik, F.; Hartmann, L.; Rademacher, C.; Chakkumkal, A.; Seeberger, P. H.: Multivalent display of minimal Clostridium difficile glycan epitopes mimics antigenic properties of larger glycans. Nature Communications 7, 11224 (2016)
  5. Bröcker, F.; Martin, C. E.; Wegner, E.; Mattner, J.; Baek, J. Y.; Pereira, C. L.; Chakkumkal, A.; Seeberger, P. H.: Synthetic Lipoteichoic Acid Glycans Are Potential Vaccine Candidates to Protect from Clostridium difficile Infections. Cell Chemical Biology 23 (8), S. 1014 - 1022 (2016)
  6. Geißner, A.; Pereira, C. L.; Leddermann, M.; Chakkumkal, A.; Seeberger, P. H.: Deciphering Antigenic Determinants of Streptococcus pneumoniae Serotype 4 Capsular Polysaccharide using Synthetic Oligosaccharides. ACS Chemical Biology 11 (2), S. 335 - 344 (2016)
  7. Möginger, U.; Resemann, A.; Martin, C. E.; Parameswarappa, S.; Govindan, S.; Wamhoff, E.-C.; Broecker, F.; Suckau, D.; Pereira, C. L.; Chakkumkal, A. et al.; Seeberger, P. H.; Kolarich, D.: Cross Reactive Material 197 glycoconjugate vaccines contain privileged conjugation sites. Scientific Reports 6, 20488 (2016)
  8. Parameswarappa, S. G.; Reppe, K.; Geißner, A.; Ménová, P.; Govindan, S.; Calow, A. D. J.; Wahlbrink, A.; Weishaupt, M. W.; Monnanda, B. P.; Bell, R. et al.; Pirofski, L.-A.; Suttorp, N.; Sander, L.; Witzenrath, M.; Pereira, C. L.; Chakkumkal, A.; Seeberger, P. H.: A Semi-synthetic Oligosaccharide Conjugate Vaccine Candidate Confers Protection against Streptococcus pneumoniae Serotype 3 Infection. Cell Chemical Biology 23 (11), S. 1407 - 1416 (2016)
  9. Reinhardt, A.; Wehle, M.; Geißner, A.; Crouch, E. C.; Kang, Y.; Yang, Y.; Chakkumkal, A.; Santer, M.; Seeberger, P. H.: Structure binding relationship of human surfactant protein D and various lipopolysaccharide inner core structures. Journal of Structural Biology 195 (3), S. 387 - 395 (2016)
  10. Wörmann, X.; Lesch, M.; Welke, R.-W.; Okonechnikov, K.; Abdurishid, M.; Sieben, C.; Geißner, A.; Brinkmann, V.; Kastner, M.; Karner, A. et al.; Zhu, R.; Hinterdorfer, P.; Chakkumkal, A.; Seeberger, P. H.; Herrmann, A.; Meyer, T. F.; Karlas, A.: Genetic characterization of an adapted pandemic 2009 H1N1 influenza virus that reveals improved replication rates in human lung epithelial cells. Virology 492, S. 118 - 129 (2016)
  11. 2015
    Pereira, C. L.; Geißner, A.; Chakkumkal, A.; Seeberger, P. H.: Chemical Synthesis Elucidates the Immunological Importance of a Pyruvate Modification in the Capsular Polysaccharide of Streptococcus pneumoniae Serotype 4. Angewandte Chemie, International Edition in English 54, S. 10016 - 10019 (2015)
  12. Pereira, C. L.; Geißner, A.; Chakkumkal, A.; Seeberger, P. H.: Synthetische Oligosaccharide belegen die immunologische Bedeutung der Pyruvatmodifikation im Kapselpolysaccharid von Serotyp 4 Streptococcus pneumoniae. Angewandte Chemie 127 (34), S. 10154 - 10157 (2015)
  13. Reinhardt, A.; Yang, Y.; Claus, H.; Pereira, C. L.; Cox, A. D.; Vogel, U.; Anish, C.; Seeberger, P. H.: Antigenic Potential of a Highly Conserved Neisseria meningitidis Lipopolysaccharide Inner Core Structure Defined by Chemical Synthesis. Chemistry & Biology 22 (1), S. 38 - 49 (2015)
  14. Zacco, E.; Chakkumkal, A.; Martin, C. E.; von Berlepsch, H.; Brandenburg, E.; Seeberger, P. H.; Koksch, B.: A Self-Assembling Peptide Scaffold for the Multivalent Presentation of Antigens. Biomacromolecules 16 (7), S. 2188 - 2197 (2015)
  15. 2014
    Anish, C.; Schumann, B.; Pereira, C. L.; Seeberger, P. H.: Chemical Biology Approaches to Designing Defined Carbohydrate Vaccines. Chemistry & Biology 21 (1), S. 38 - 50 (2014)
  16. Bröcker, F.; Aretz, J.; Yang, Y.; Hanske, J.; Guo, X.; Reinhardt, A.; Wahlbrink, A.; Rademacher, C.; Anish, C.; Seeberger, P. H.: Epitope Recognition of Antibodies against a Yersinia pestis Lipopolysaccharide Trisaccharide Component. ACS Chemical Biology 9 (4), S. 867 - 873 (2014)
  17. Geißner, A.; Anish, C.; Seeberger, P. H.: Glycan arrays as tools for infectious disease research. Current Opinion in Chemical Biology 18, S. 38 - 45 (2014)
  18. Götze, S.; Azzouz, N.; Tsai, Y.-H.; Groß, U.; Reinhardt, A.; Anish, C.; Seeberger, P. H.; Silva, D. V.: Diagnosis of Toxoplasmosis Using a Synthetic Glycosylphosphatidylinositol Glycan. Angewandte Chemie, International Edition in English 53 (50), S. 13701 - 13705 (2014)
  19. Schumann, B.; Pragani, R.; Anish, C.; Pereira, C. L.; Seeberger, P. H.: Synthesis of conjugation-ready zwitterionic oligosaccharides by chemoselective thioglycoside activation. Chemical Science 5 (5), S. 1992 - 2002 (2014)
  20. 2013
    Anish, C.; Martin, C. E.; Wahlbrink, A.; Bogdan, C.; Ntais, P.; Antoniou, M.; Seeberger, P. H.: Immunogenicity and Diagnostic Potential of Synthetic Antigenic Cell Surface Glycans of Leishmania. ACS CHEMICAL BIOLOGY 8 (11), S. 2412 - 2422 (2013)
 
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