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Zeitschriftenartikel (24)

  1. 2018
    Baek, J. Y.; Geissner, A.; Rathwell, D. C. K.; Meierhofer, D.; Pereira, C. L.; Seeberger, P. H.: A modular synthetic route to size-defined immunogenic Haemophilus influenzae b antigens is key to the identification of an octasaccharide lead vaccine candidate. Chemical Science 9 (5), S. 1279 - 1288 (2018)
  2. Bröcker, F.; Götze, S.; Hudon, J.; Rathwell, D. C. K.; Pereira, C. L.; Stallforth, P.; Chakkumkal, A.; Seeberger, P. H.: Synthesis, Liposomal Formulation, and Immunological Evaluation of a Minimalistic Carbohydrate-α-GalCer Vaccine Candidate. Journal of Medicinal Chemistry 61 (11), S. 4918 - 4927 (2018)
  3. Menova, P.; Sella, M.; Sellrie, K.; Pereira, C. L.; Seeberger, P. H.: Identification of the Minimal Glycotope of Streptococcus pneumoniae 7F Capsular Polysaccharide using Synthetic Oligosaccharides. Chemistry – A European Journal 24 (16), S. 4181 - 4187 (2018)
  4. Qin, C.; Schumann, B.; Zou, X.; Pereira, C. L.; Tian, G.; Hu, J.; Seeberger, P. H.; Yin, J.: Total Synthesis of a Densely Functionalized Plesiomonas shigelloides Serotype 51 Aminoglycoside Trisaccharide Antigen. Journal of the American Chemical Society 140 (8), S. 3120 - 3127 (2018)
  5. Schumann, B.; Reppe, K.; Kaplonek, P.; Wahlbrink, A.; Chakkumkal, A.; Witzenrath, M.; Pereira, C. L.; Seeberger, P. H.: Development of an Efficacious, Semisynthetic Glycoconjugate Vaccine Candidate against Streptococcus pneumoniae Serotype 1. ACS Central Science 4 (3), S. 357 - 361 (2018)
  6. Zou, X.; Qin, C.; Pereira, C. L.; Tian, G.; Hu, J.; Seeberger, P. H.; Yin, J.: Synergistic Glycosylation as Key to the Chemical Synthesis of an Outer Core Octasaccharide of Helicobacter pylori. Chemistry – A European Journal 24 (12), S. 2868 - 2872 (2018)
  7. 2017
    Emmadi, M.; Khan, N.; Lykke, L.; Reppe, K.; Parameswarappa, S.; Lisboa, M. P.; Wienhold, S.-M.; Witzenrath, M.; Pereira, C. L.; Seeberger, P. H.: A Streptococcus pneumoniae Type 2 Oligosaccharide Glycoconjugate Elicits Opsonic Antibodies and Is Protective in an Animal Model of Invasive Pneumococcal Disease. Journal of the American Chemical Society 139 (41), S. 14783 - 14791 (2017)
  8. Lisboa, M. P.; Khan, N.; Martin, C.; Xu, F.-F.; Reppe, K.; Geissner, A.; Govindan, S.; Witzenrath, M.; Pereira, C. L.; Seeberger, P. H.: Semisynthetic glycoconjugate vaccine candidate against Streptococcus pneumoniae serotype 5. Proceedings of the National Academy of Sciences of the United States of America 114 (42), S. 11063 - 11068 (2017)
  9. Schumann, B.; Hahm, H. S.; Parameswarappa, S. G.; Reppe, K.; Wahlbrink, A.; Govindan, S.; Kaplonek, P.; Pirofski, L.-a.; Witzenrath, M.; Chakkumkal, A. et al.; Pereira, C. L.; Seeberger, P. H.: A semisynthetic Streptococcus pneumoniae serotype 8 glycoconjugate vaccine. Science Translational Medicine 9 (380), eaaf5347 (2017)
  10. Seeberger, P. H.; Pereira, C. L.; Khan, N.; Xiao, G.; Diago-Navarro, E.; Reppe, K.; Opitz, B.; Fries, B. C.; Witzenrath, M.: A Semi-Synthetic Glycoconjugate Vaccine Candidate for Carbapenem-Resistant Klebsiella pneumoniae. Angewandte Chemie 129 (45), S. 14161 - 14166 (2017)
  11. Xu, F.-F.; Pereira, C. L.; Seeberger, P. H.: 1,3-Dibromo-5,5-dimethylhydantoin as promoter for glycosylations using thioglycosides. Beilstein Journal of Organic Chemistry 13, S. 1994 - 1998 (2017)
  12. 2016
    Bröcker, F.; Martin, C. E.; Wegner, E.; Mattner, J.; Baek, J. Y.; Pereira, C. L.; Chakkumkal, A.; Seeberger, P. H.: Synthetic Lipoteichoic Acid Glycans Are Potential Vaccine Candidates to Protect from Clostridium difficile Infections. Cell Chemical Biology 23 (8), S. 1014 - 1022 (2016)
  13. Geißner, A.; Pereira, C. L.; Leddermann, M.; Chakkumkal, A.; Seeberger, P. H.: Deciphering Antigenic Determinants of Streptococcus pneumoniae Serotype 4 Capsular Polysaccharide using Synthetic Oligosaccharides. ACS Chemical Biology 11 (2), S. 335 - 344 (2016)
  14. Möginger, U.; Resemann, A.; Martin, C. E.; Parameswarappa, S.; Govindan, S.; Wamhoff, E.-C.; Broecker, F.; Suckau, D.; Pereira, C. L.; Chakkumkal, A. et al.; Seeberger, P. H.; Kolarich, D.: Cross Reactive Material 197 glycoconjugate vaccines contain privileged conjugation sites. Scientific Reports 6, 20488 (2016)
  15. Parameswarappa, S. G.; Reppe, K.; Geißner, A.; Ménová, P.; Govindan, S.; Calow, A. D. J.; Wahlbrink, A.; Weishaupt, M. W.; Monnanda, B. P.; Bell, R. et al.; Pirofski, L.-A.; Suttorp, N.; Sander, L.; Witzenrath, M.; Pereira, C. L.; Chakkumkal, A.; Seeberger, P. H.: A Semi-synthetic Oligosaccharide Conjugate Vaccine Candidate Confers Protection against Streptococcus pneumoniae Serotype 3 Infection. Cell Chemical Biology 23 (11), S. 1407 - 1416 (2016)
  16. Schumann, B.; Parameswarappa, S.; Lisboa, M. P.; Kottari, N.; Guidetti, F.; Pereira, C. L.; Seeberger, P. H.: Nucleophil-dirigierte Stereokontrolle über Glykosylierungsreaktionen durch geminal-difluorierte Nucleophile. Angewandte Chemie 128 (46), S. 14644 - 14648 (2016)
  17. Schumann, B.; Parameswarappa, S.; Lisboa, M. P.; Kottari, N.; Guidetti, F.; Pereira, C. L.; Seeberger, P. H.: Nucleophile-Directed Stereocontrol Over Glycosylations Using Geminal-Difluorinated Nucleophiles. Angewandte Chemie International Edition 55 (46), S. 14431 - 14434 (2016)
  18. Weishaupt, M. W.; Matthies, S.; Hurevich, M.; Pereira, C. L.; Hahm, H. S.; Seeberger, P. H.: Automated glycan assembly of a S. pneumoniae serotype 3 CPS antigen. Beilstein Journal of Organic Chemistry 12, S. 1440 - 1446 (2016)
  19. 2015
    Pereira, C. L.; Geißner, A.; Chakkumkal, A.; Seeberger, P. H.: Chemical Synthesis Elucidates the Immunological Importance of a Pyruvate Modification in the Capsular Polysaccharide of Streptococcus pneumoniae Serotype 4. Angewandte Chemie, International Edition in English 54, S. 10016 - 10019 (2015)
  20. Pereira, C. L.; Geißner, A.; Chakkumkal, A.; Seeberger, P. H.: Synthetische Oligosaccharide belegen die immunologische Bedeutung der Pyruvatmodifikation im Kapselpolysaccharid von Serotyp 4 Streptococcus pneumoniae. Angewandte Chemie 127 (34), S. 10154 - 10157 (2015)
 
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