|
(a) State space of two-headed motor consisting of 9 motor states that differ in the chemical composition of the two heads: Each head can be empty (E),
contain an ATP molecule (T) or an ADP molecule (D). The solid lines represent chemical transitions,
which change the chemical composition;
the broken line represents a mechanical transition, during which the two head interchange their relative position;
(b) Reduced 7-state network without the strongly bound EE and TT states. The black arrow indicates the direction of the mechanical forward transition, the white double arrows indicate ATP hydrolysis transitions; and (c) Reduced 6-state network without the loosely bound DD state.
>> Original publication:
Kinesin's network of
chemomechanical motor cycles
|