Publikationen von Christoph Rademacher

Denavit, V.; Lainé, D.; Bouzriba, C.; Shanina, E.; Gillon, É.; Fortin, S.; Rademacher, C.; Imberty, A.; Giguére, D.: Stereoselective synthesis of fluorinated galactopyranosides as potential molecular probes on galactophilic proteins: assessment of monofluorogalactosides-LecA interactions. Chemistry – A European Journal 25 (17), S. 4478 - 4490 (2019)

Freichel, T.; Laaf, D.; Hoffmann, M.; Konietzny, P. B.; Heine, V.; Wawrzinek, R.; Rademacher, C.; Snyder, N. L.; Elling, L.; Hartmann, L.: Effects of linker and liposome anchoring on lactose-functionalized glycomacromolecules as multivalent ligands for binding galectin-3. RSC Advances 9 (41), S. 23484 - 23497 (2019)

Geißner, A.; Reinhardt, A.; Rademacher, C.; Johannssen, T.; Monteiro, J.; Lepenies, B.; Thépaut, M.; Fieschi, F.; Mrázková, J.; Wimmerova, M. et al.; Schuhmacher, F.; Götze, S.; Grünstein, D.; Guo, X.; Hahm, H. S.; Kandasamy, J.; Leonori, D.; Martin, C. E.; Parameswarappa, S. G.; Pasari,, S.; Schlegel, M. K.; Tanaka, H.; Xiao, G.; Yang, Y.; Pereira, C. L.; Anish, C.; Seeberger, P. H.: Microbe-focused glycan array screening platform. Proceedings of the National Academy of Sciences of the United States of America 116 (6), S. 1958 - 1967 (2019)

Neuhaus, K.; Wamhoff, E.-C.; Freichel, T.; Grafmüller, A.; Rademacher, C.; Hartmann, L.: Asymmetrically branched precision glycooligomers targeting langerin. Biomacromolecules 20 (11), S. 4088 - 4095 (2019)

Schulze, J.; Rentzsch, M.; Kim, D.; Bellmann, L.; Stoitzner, P.; Rademacher, C.: A Liposomal Platform for Delivery of a Protein Antigen to Langerin-Expressing Cells. Biochemistry 58 (21), S. 2576 - 2580 (2019)

van Dalen, R.; La Diaz, J. S. D. C.; Rumpret, M.; Fuchsberger, F. F.; van Teijlingen, N. H.; Hanske, J.; Rademacher, C.; Geijtenbeek, T. B. H.; van Strijp, J. A. G.; Weidenmaier, C. et al.; Peschel, A.; Kaplan, D. H.; van Sorge, N. M.: Langerhans cells sense staphylococcus aureus wall teichoic acid through langerin to induce inflammatory responses. mBio 10 (3), e00330-19 (2019)

Wamhoff, E.-C.; Schulze, J.; Bellmann, L.; Rentzsch, M.; Bachem, G.; Fuchsberger, F. F.; Rademacher, J.; Hermann, M.; Del Frari, B.; van Dalen, R. et al.; Hartmann, D.; van Sorge, N.; Seitz, O.; Stoitzner, P.; Rademacher, C.: A specific, glycomimetic Langerin ligand for human Langerhans cell targeting. ACS Central Science 5 (5), S. 808 - 820 (2019)

Aretz, J.; Anumala, U. R.; Fuchsberger, F. F.; Molavi, N.; Ziebart, N.; Zhang, H.; Nazaré, M.; Rademacher, C.: Allosteric inhibition of a mammalian lectin. Journal of the American Chemical Society 140 (44), S. 14915 - 14925 (2018)

Ng, S.; Bennett, N. J.; Schulze, J.; Gao, N.; Rademacher, C.; Derda, R.: Genetically-encoded fragment-based discovery of glycopeptide ligands for DC-SIGN. Bioorganic & Medicinal Chemistry 26 (19), S. 5368 - 5377 (2018)

Ota, F.; Hirayama, T.; Kizuka, Y.; Yamaguchi, Y.; Fujinawa, R.; Nagata, M.; Ismanto, H. S.; Lepenies, B.; Aretz, J.; Rademacher, C. et al.; Seeberger, P. H.; Angata, T.; Kitazume, S.; Yoshida, K.; Betsuyaku, T.; Kida, K.; Yamasaki, S.; Taniguchi, N.: High affinity sugar ligands of C-type lectin receptor langerin. Biochimica et Biophysica Acta (BBA) - General Subjects 1862 (7), S. 1592 - 1601 (2018)

Schulze, J.; Baukmann, H.; Wawrzinek, R.; Fuchsberger, F. F.; Specker, E.; Aretz, J.; Nazaré, M.; Rademacher, C.: CellFy: a cell-based fragment screen against C-type lectins. ACS Chemical Biology 13 (12), S. 3229 - 3235 (2018)

Sommer, R.; Wagner, S.; Rox, K.; Varrot, A.; Hauck, D.; Wamhoff, E.-C.; Schreiber, J.; Ryckmans, T.; Brunner, T.; Rademacher, C. et al.; Hartmann, R. W.; Brönstrup, M.; Imberty, A.; Titz, A.: Glycomimetic, orally bioavailable LecB inhibitors block biofilm formation of Pseudomonas aeruginosa. Journal of the American Chemical Society 140 (7), S. 2537 - 2545 (2018)

Tian, G.-Z.; Hu, J.; Zhang, H.-X.; Rademacher, C.; Zou, X.-P.; Zheng, H.-N.; Xu, F.; Wang, X.-L.; Yin, T. L. &. J.: Synthesis and conformational analysis of linear homo- and heterooligomers from novel 2-C-branched sugar amino acids (SAAs). Scientific Reports 8, 6625 (2018)

Aretz, J.; Baukmann, H.; Shanina, E.; Hanske, J.; Wawrzinek, R.; Zapol'skii, V. A.; Seeberger, P. H.; Kaufmann, D. E.; Rademacher, C.: Identification of multiple druggable secondary sites by fragment screening against DC-SIGN. Angewandte Chemie International Edition 56 (25), S. 7292 - 7296 (2017)

Gao, C.; Fujinawa, R.; Yoshida, T.; Ueno, M.; Ota, F.; Kizuka, Y.; Hirayama, T.; Korekane, H.; Kitazume, S.; Maeno, T. et al.; Ohtsubo, K.; Yoshida, K.; Yamaguchi, Y.; Lepenies, B.; Aretz, J.; Rademacher, C.; Kabata, H.; Hegab, A. E.; Seeberger, P. H.; Betsuyaku, T.; Kida, K.; Taniguchi, N.: A keratan sulfate disaccharide prevents inflammation and the progression of emphysema in murine models. American Journal of Physiology - Lung Cellular and Molecular Physiology 312 (2), S. L268 - L276 (2017)

Glas, A.; Wamhoff, E.-C.; Krüger, D. M.; Rademacher, C.; Grossmann, T. N.: Increased conformational flexibility of a macrocycle‒receptor complex contributes to reduced dissociation rates. Chemistry – A European Journal 23 (64), S. 16157 - 16161 (2017)

Hanske, J.; Schulze, J.; Aretz, J.; McBride, R.; Loll, B.; Schmidt, H.; Knirel, Y.; Rabsch, W.; Wahl, M. C.; Paulson, J. C. et al.; Rademacher, C.: Bacterial polysaccharide specificity of the pattern recognition receptor langerin is highly species-dependent. The Journal of Biological Chemistry 292 (3), S. 862 - 871 (2017)

Hanske, J.; Wawrzinek, R.; Geissner, A.; Wamhoff, E.-C.; Sellrie, K.; Schmidt, H.; Seeberger, P. H.; Rademacher, C.: Calcium-independent activation of an allosteric network in Langerin by heparin oligosaccharides. ChemBioChem: A European Journal of Chemical Biology 18 (13), S. 1183 - 1187 (2017)

Spiliotopoulos, D.; Wamhoff, E.-C.; Lolli, G.; Rademacher, C.; Caflisch, A.: Discovery of BAZ2A bromodomain ligands. European Journal of Medicinal Chemistry 139 (Supplement C), S. 564 - 572 (2017)

Spiliotopoulos, D.; Zhu, J.; Wamhoff, E.-C.; Deerain, N.; Marchand, J.-R.; Aretz, J.; Rademacher, C.; Caflisch, A.: Virtual screen to NMR (VS2NMR): discovery of fragment hits for the CBP bromodomain. Bioorganic & Medicinal Chemistry Letters 27 (11), S. 2472 - 2478 (2017)