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DIMOVA LAB

Biomembranes and more

Last modified:  16/11/16, 10:50 AM

Since more than a decade now, giant vesicles are objects that fascinate and, at times, surprise us. These giants are only a few tens of microns in size and this defines their unique property: they are visible under a light microscope and provide a handy biomimetic tool for displaying directly the response of the membrane on the cell-size scale. Our group employs them for systematic measurements of the properties of lipid bilayers as a function of membrane composition and phase state, surrounding media, and temperature. We also investigate membrane responses to external factors such as ions, amphiphilic (biomacro)molecules and polymers, membrane-wetting aqueous phases, hydrodynamic flows or electromagnetic fields. The objectives of our group are to understand fundamental cellular phenomena and morphologies of cell organelles as well as to identify general mechanisms underlying cellular processes.

…And apart from being focused on our work, we also have fun.

News

GM1 softens POPC membranes and induces the formation of micron-sized domains, Fricke & Dimova, Biophys. J. 111:1935 (2016) DOI: 10.1016/j.bpj.2016.09.028

Modulating vesicle adhesion by electric fields, Steinkühler et al., Biophys. J. 111:1454 (2016) DOI: 10.1016/j.bpj.2016.08.029

Solution asymmetry and salt expand fluid-fluid coexistence regions of charged membranes, Kubsch et al., Biophys. J. 110:2581 (2016) DOI:10.1016/j.bpj.2016.05.028


Latest articles

May, 2016: Chathuri Wijekoon and Amanda Jack joined the lab.

May 7, 2016: Group retreat: photos

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