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Biomembranes and more

Last modified:  6/3/18, 10:50 AM

Since more than a decade now, giant vesicles are objects that fascinate and, at times, surprise us. These giants are only a few tens of microns in size and this defines their unique property: they are visible under a light microscope and provide a handy biomimetic tool for displaying directly the response of the membrane on the cell-size scale. Our group employs them for systematic measurements of the properties of lipid bilayers as a function of membrane composition and phase state, surrounding media, and temperature. We also investigate membrane responses to external factors such as ions, amphiphilic (biomacro)molecules and polymers, membrane-wetting aqueous phases, hydrodynamic flows or electromagnetic fields. The objectives of our group are to understand fundamental cellular phenomena and morphologies of cell organelles as well as to identify general mechanisms underlying cellular processes.

…And apart from being focused on our work, we also have fun.


Dynamic blue light-switchable protein patterns on giant unilamellar vesicles, Bartlet et al., Chem Commun 54:948 (2018) DOI: 10.1039/C7CC08758F

Sequential bottom-up assembly of mechanically stabilized synthetic cells by microfluidics, Weiss et al., Nature Materials 17:89 (2018) DOI: 10.1038/nmat5005

Phase behavior of charged vesicles under symmetric and asymmetric solution conditions monitored with fluorescence microscopy, Kubsch et al., JoVE 128:e56034 (2017) DOI:10.3791/56034

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March, 2018: Shelli Frey joined the lab

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