Publications

30) C. Ruprecht, A. Geissner, P. H. Seeberger, F. Pfrengle*, "Practical considerations for printing high-density glycan microarrays to study weak carbohydrate-protein interactions", Carb. Res. 2019, in press.

29) M. P. Bartetzko, F. Pfrengle*, “Automated Glycan Assembly of Plant Oligosaccharides and Their Application in Cell Wall Biology“, ChemBioChem 2019, 20, 877-885. 

28) D. Senf, C. Ruprecht, S. Kishani, A. Matic, G. Toriz, P. Gatenholm, L. Wagberg, F. Pfrengle*, “Tailormade Polysaccharides with Defined Branching Patterns: Enzymatic Polymerization of Arabinoxylan Oligosaccharides”, Angew. Chem. Int. Ed. 2018, 57, 11987-11992.

27) C. Ruprecht, P. Dallabernardina, P. J. Smith, B. R. Urbanowicz, F. Pfrengle*, "Analyzing Xyloglucan Endotransglycosylases by Incorporation of Synthetic Oligosaccharides into Plant Cell Walls", ChemBioChem 2018, 19, 793-798.

26) P. Dallabernardina, C. Ruprecht, P. J. Smith, M. G. Hahn, B. R. Urbanowicz, F. Pfrengle*, "Automated glycan assembly of galactosylated xyloglucan oligosaccharides and their recognition by plant cell wall glycan-directed antibodies", Org. Biomol. Chem. 2017, 15, 9996-10000.

25) M. C. F. Andersen, I. Boos, C. Ruprecht, W. G. T. Willats, F. Pfrengle, M. H. Clausen, "Synthesis and Application of Branched Type II Arabinogalactans", J. Org. Chem. 2017, 82, 12066-12084.

24) C. Ruprecht, M. P. Bartetzko, D. Senf, P. Dallabernadina, I. Boos, M. C. F. Andersen, T. Kotake, J. P. Knox, M. G. Hahn, M. H. Clausen, F. Pfrengle*, A synthetic glycan microarray enables epitope mapping of plant cell wall glycan-directed antibodies. Plant Physiol. 2017, 175, 1094-1104.

23) F. Pfrengle*, Synthetic Plant Glycans, Curr. Opin. Chem. Biol. 2017, 40, 145-151 (Review).

22) D. Senf, C. Ruprecht, Goswinus H. M. de Kruijff, S. O. Simonetti, F. Schuhmacher, P. H. Seeberger, F. Pfrengle*, Active Site-Mapping of Xylan-Deconstructing Enzymes with Arabinoxylan Oligosaccharides Produced by Automated Glycan Assembly. Chem. Eur. J. 2017, 23, 3197-3205.

21) M. P. Bartetzko, F. Schuhmacher, P. H. Seeberger, F. Pfrengle*, Determining Substrate Specificities of β1,4-Endo-Galactanases Using Plant Arabinogalactan Oligosaccharides Synthesized by Automated Glycan Assembly. J. Org. Chem. 2017, 82, 1842-1850.

20) P. Dallabernardina, F. Schuhmacher, P. H. Seeberger, F. Pfrengle*, Mixed-Linkage Glucan Oligosaccharides Produced by Automated Glycan Assembly Serve as Tools to Determine the Substrate Specificity of Lichenase. Chem. Eur. J. 2017, 23, 3191-3196.

19) M. Wilsdorf, D. Schmidt, M. P. Bartetzko, P. Dallabernardina, F. Schuhmacher, P. H. Seeberger, F. Pfrengle*, A traceless photocleavable linker for the automated glycan assembly of carbohydrates with free reducing ends. Chem. Commun. 2016, 52, 10187-10189.

18) P. Dallabernardina, F. Schuhmacher, P. H. Seeberger, F. Pfrengle*, Automated Glycan Assembly of Xyloglucan Oligosaccharides. Org. Biomol. Chem. 2016, 14, 309-313.

17) M. P. Bartetzko, F. Schuhmacher, H. S. Hahm, P. H. Seeberger, F. Pfrengle*, Automated Glycan Assembly of Oligosaccharides Related to Arabinogalactan Proteins. Org. Lett. 2015, 17, 4344-4347.

16) D. Schmidt, F. Schuhmacher, A. Geissner, P. H. Seeberger, F. Pfrengle*, Automated Synthesis of Arabinoxylan-Oligosaccharides Enables Characterization of Antibodies that Recognize Plant Cell Wall Glycans. Chem. Eur. J. 2015, 21, 5709-5713.

As postdoc:

15) M. S. Macauley, F. Pfrengle, C. Rademacher, C. M. Nycholat, A. J. Gale, A. von Drygalski, J. C. Paulson, Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis. J. Clin. Invest. 2013, 123, 3074-3083. Highlighted in: L. Nitschke N. Engl. J. Med. 2013, 369, 1373-74.

14) F. Pfrengle, M. S. Macauley, N. Kawasaki, J. C. Paulson, Copresentation of Antigen and Ligands of Siglec-G Induces B Cell Tolerance Independent of CD22. J. Immunol. 2013, 191, 1724-1731.

As PhD-student:

13) T. Lechel, F. Pfrengle, H.-U. Reissig, R. Zimmer, Three Carbons for Complexity! Recent Developments on Palladium-Catalyzed Reactions of Allenes. ChemCatChem 2013, 5, 2100-2130.

12) M. Roskamp, S. Enders, F. Pfrengle, S. Yekta, V. Dekaris, J. Dernedde, H.-U. Reissig, S. Schlecht, Multivalent Interaction and Selectivities in Selectin Binding of Functionalized Gold Colloids Decorated with Carbohydrate Mimetics. Org. Biomol. Chem. 2011, 9, 7448-7456.

11) F. Pfrengle, H.-U. Reissig, Addition of lithiated enol ethers to nitrones and subsequent Lewis acid induced cyclizations to enantiopure 3,6-dihydro-2H-pyrans - an approach to carbohydrate mimetics. Beilstein J. Org. Chem. 2010, 6, No. 75.

10) F. Pfrengle, H.-U. Reissig, Internally Protected Amino Sugar Equivalents from Enantiopure 1,2-Oxazines: Synthesis of Variably Configured Carbohydrates with C-Branched Amino Sugar Units. Chem. Eur. J. 2010, 16, 11915-11925.

9) F. Pfrengle, H.-U. Reissig, Amino sugars and their mimetics via 1,2-oxazines. Chem. Soc. Rev. 2010, 39, 549-557.

8) F. Pfrengle, D. Lentz, H.-U. Reissig, A New Ring Closure Approach to Enantiopure 3,6-Dihydro-2H-pyrans – Stereodivergent Access to Carbohydrate Mimetics. Org. Lett. 2009, 11, 5534-5537.

7) A. Al-Harrasi, F. Pfrengle, V. Prisyashnyuk, S. Yekta, P. Koóš, H.-U. Reissig, Enantiopure Aminopyrans by a Lewis Acid Promoted Rearrangement of 1,2-Oxazines: Versatile Building Blocks for Oligosaccharide and Sugar Amino Acid Mimetics. Chem. Eur. J. 2009, 15, 11632-11641.

6) F. Pfrengle, D. Lentz, H.-U. Reissig, Stereodivergent De Novo Synthesis of Branched Amino Sugars by Lewis Acid Promoted Rearrangement of 1,2-Oxazines. Angew. Chem. Int. Ed. 2009, 48, 3165-3169.

5) F. Pfrengle, A. Al-Harrasi, I. Brüdgam, H.-U. Reissig, Unusual Heterocyclic Skeletons via Lewis Acid Promoted Rearrangements of 1,3-Dioxolanyl-Substituted 1,2-Oxazines. Eur. J. Org. Chem. 2009, 282-291.

4) F. Pfrengle, V. Dekaris, L. Schefzig, R. Zimmer, H.-U. Reissig, Indium Trichloride Mediated Cleavage of Acetonides in the Presence of Acid-Labile Functional Groups – Enhancing the Synthetic Utility of 1,3-Dioxolanyl-Substituted 1,2-Oxazines. Synlett 2008, 2965-2968. Highlighted: Synfacts 2009, 251.

Before PhD-thesis:

3) F. Pfrengle, A. Al-Harrasi, H.-U. Reissig, Lewis Acid Promoted Rearrangements of 1,3-Dioxolanyl-Substituted 1,2-Oxazines into Novel Products with 1,3,6-Trioxa-7-azacyclopenta[cd]indene Skeletons. Synlett 2006, 3498-3500.

Book chapters:

2) F. Pfrengle*, Solid-phase glycan synthesis. In “Synthetic glycomes”, The Royal Society of Chemistry, 2019, 331-355.

1) F. Pfrengle*, P. H. Seeberger*, Orthogonally protected building blocks for automated glycan assembly. In “Protecting Groups: Strategies and Applications in Carbohydrate Chemistry”, WILEY-VCH, 2018, 451-471.

Patents:

J. C. Paulson, M. S. Macauley, F. Pfrengle, Methods and Compositions for Treating Bleeding Disorders. US Patent Application #20160060324.

 
loading content
Go to Editor View