Morphological Transitions of Vesicles (Budding, Tubulation, ...)

    Vesicles are closed membrane "bags" that exhibit a large variety of different shapes and morphological transitions between these shapes. [1] [2] Such transitions can be induced, e.g., by small changes in temperature or osmotic conditions. [3] Particularly interesting examples are provided by domain-induced budding [4] [5], conformal diffusion [6], adhesion [7], and fusion [8] processes. Morphological transitions are also induced by ionic solutions in alternating electric fields [9] and by aqueous solutions that form two coexisting liquid phases [10]. For a recent review, see [11]

  • R. Lipowsky
    Coupling of bending and stretching deformations in vesicle membranes.
     Adv. Colloid Interface Sci. 208, 14-24 (2014).

  • R. Lipowsky
    Remodelling of membrane compartments: some consequences of membrane fluidity.
     Biol. Chem. 395, 253-274 (2014).

  • R. Lipowsky
    Spontaneous tubulation of membranes and vesicles reveals membrane tension generated by spontaneous curvature.
    Spontaneous tubulation of membranes and vesicles ... - Corrections.
    Spontaneous tubulation of membranes and vesicles... - Supporting Information.
    Faraday Discuss. 161, 305-331 (2013).

  • A. H. Bahrami, R. Lipowsky, and T. Weikl
    Tubulation and aggregation of spherical nanoparticles adsorbed on vesicles.
     Phys. Rev. Lett. 109, 188102 (2012)

  • R. Knorr, R. Dimova, and R. Lipowsky
    Curvature of double-membrane organelles generated by changes in membrane size and composition.
     Curvature of double-membrane organelles ... - Supporting Information.
     PLoS ONE 7, e32753 (2012).

  • Yanhong Li, H. Kusumaatmaja, R. Lipowsky, and R. Dimova
    Wetting-induced budding of vesicles in contact with several aqueous phases.
     J. Phys. Chem. B 116, 1819-1823 (2012).

  • H. Kusumaatmaja and R. Lipowsky
    Droplet-induced budding transitions of membranes.
     Soft Matter 7, 6914-6919 (2011).

  • Yanhong Li, R. Lipowsky, and R. Dimova
    Membrane nanotubes induced by aqueous phase separation and stabilized by spontaneous curvature.
     Membrane nanotubes induced by aqueous phase separation ... - Supporting Information.
     PNAS 108, 4731-4736 (2011).

  • T. Yamamoto, S. Aranda, R. Dimova, and R. Lipowsky
    Stability of spherical vesicles in electric fields.
     Langmuir 26, 12390-12407 (2010).

  • R. Gracia, N. Bezlyepkina, R. L. Knorr, R. Lipowsky, and R. Dimova
    Effect of cholesterol on the rigidity of saturated and unsaturated membranes: fluctuation and electrodeformation analysis of giant vesicles.
     Soft Matter 6, 1472-1482 (2010).

  • H. Kusumaatmaja, Y.-H. Li, R. Dimova, and R. Lipowsky
    Intrinsic contact angle of aqueous phases at membranes and vesicles.
     Phys. Rev. Lett. 103, 238103 (2009)

  • E. Gutlederer, T. Gruhn, and R. Lipowsky
    Polymorphism of vesicles with multi-domain patterns.
    Soft Matter 5, 3303 - 3311 (2009).

  • M. Staykova, R. Lipowsky, and R. Dimova
    Membrane flow patterns in multicomponent giant vesicles induced by alternating electric fields.
     Membrane flow patterns in multicomponent giant vesicles ... - Supporting Information.
     Soft Matter 4, 2168-2171 (2008)

  • Y.-H. Li, R. Lipowsky, and R. Dimova
    Transition from complete to partial wetting within membrane compartments.
     Transitions from complete to partial wetting ... - Supporting Information.
     JACS 130, 12252-12253 (2008).

  • S. Aranda, K. A. Riske, R. Lipowsky, and R. Dimova
    Morphological transitions of vesicles induced by alternating electric fields.
     Biophys. J. 95, L19-L21 (2008).

  • G. Linke, R. Lipowsky, and T. Gruhn
    Adhesion of fluid vesicles at chemically structured substrates.
     Eur. Phys. J. E24, 217-227 (2007).

  • R. Dimova, K.A. Riske, S. Aranda, N. Bezlyepkina, R.L. Knorr and R. Lipowsky
    Giant vesicles in electric fields.
     Soft Matter 3, 817 - 827 (2007).

  • V. Nikolov, R. Lipowsky and R. Dimova
    Behavior of Giant Vesicles with Anchored DNA Molecules
     Biophysical Journal 92, 4356 - 4368 (2007).

  • T. Gruhn, T. Franke, R. Dimova and R. Lipowsky
    Novel Method for Measuring the Adhesion Energy of Vesicles.
     Langmuir 23, 5423 - 5429 (2007).

  • K. A. Riske, N. Bezlyepkina, R. Lipowsky, and R. Dimova
    Electrofusion of model lipid membranes viewed with high temporal resolution.
     Biophys. Rev. Lett. 1, 387 - 400 (2006).

  • C.K. Haluska, K.A. Riske, V. Marchi-Artzner, J.-M. Lehn, R. Lipowsky and R. Dimova
    Time scales of membrane fusion revealed by direct imaging of vesicle fusion with high temporal resolution.
     Time scales of membrane fusion ... - Supporting Information.
     PNAS 103, 15841 - 15846 (2006).

  • T. Franke, R. Lipowsky and W. Helfrich
    Adhesion of lipid membranes induced by CrCl3.
    Europhys. Lett. 76, 339 - 345 (2006).

  • R. Dimova, S. Aranda, N. Bezlyepkina, V. Nikolov, K.A. Riske and R. Lipowsky
    A practical guide to giant vesicles. Probing the membrane nanoregime via optical microscopy.
     J. Phys.: Condens. Matter 18, S1151 - S1176 (2006).

  • G.T. Linke, R. Lipowsky, T. Gruhn
    Osmotically induced passage of vesicles through narrow pores.
     Europhys. Lett. 74, 916-922 (2006).

  • R. Lipowsky, M. Brinkmann, R. Dimova, C. Haluska, J. Kierfeld and J. Shillcock
    Wetting, budding, and fusion - morphological transitions of soft surfaces.
    J. Phys.: Condens. Matter 17, S2885 - S2902 (2005).

  • G.T. Linke, R. Lipowsky and T. Gruhn
    Free fluid vesicles are not exactly spherical.
     Phys. Rev. E 71, 051602 (2005).

  • R. Lipowsky, M. Brinkmann, R. Dimova, T. Franke, J. Kierfeld and X. Zhang
    Droplets, bubbles, and vesicles at chemically structured surfaces.
     J. Phys.: Condens. Matter 17, S537-S558, (2005).

  • T. Gruhn and R. Lipowsky
    Temperature dependence of vesicle adhesion.
    Phys. Rev. E 71, 011903, (2005) .

  • R. Lipowsky and R. Dimova
    Domains in membranes and vesicles.
    J. Phys.: Condens. Matter 15, S31-S45 (2003).

  • R. Lipowsky.
    Domains and Rafts in Membranes - Hidden Dimensions of Selforganization.
    J. Biological Phys. 28, 195-210 (2002).

  • P.B. Kumar, G. Gompper, and R. Lipowsky.
    Budding Dynamics of Multicomponent Membranes.
    Phys. Rev. Lett. 86 , 3911-3914 (2001).

  • R. Lipowsky.
    From Membranes to Membrane Machines.
    In ''Statistical Mechanics of Biocomplexity'',
    ed. by D. Reguera, J.M. Rubi, and J.M.B. Vilar,
    ''Lecture Notes in Physics'', Vol. 527, pages 1-23 (Springer, Berlin 1999).

  • R. Lipowsky and H.G. Döbereiner.
    Vesicles in contact with nanoparticles and colloids.
    Europhys. Lett. 43, 219-225 (1998).

  • M. Kraus, W. Wintz, U. Seifert, and R. Lipowsky.
    Fluid vesicles in shear flow.
    Phys. Rev. Lett. 77 , 3685-3688 (1996).

  • F. Jülicher and R. Lipowsky.
    Shape transformations of inhomogeneous vesicles with intramembrane domains.
    Phys. Rev. E, 53, 2670-2683 (1996).

  • R. Lipowsky.
    Kooperatives Verhalten von Membranen.
    Phys. Bl. 52 , 555-560 (1996).

  • R. Lipowsky.
    The morphology of lipid membranes.
    Current Opinion in Structural Biology 5 , 531-540 (1995).

  • M. Kraus, U. Seifert, and R. Lipowsky.
    Gravity-induced shape changes of bound vesicles.
    Europhys. Lett. 32 , 431-436 (1995).

  • U. Seifert and R. Lipowsky.
    The morphology of vesicles.
    In R. Lipowsky and E. Sackmann, editors ''Structure and Dynamics of Membranes.''
    Handbook of Biological Physics, Vol. 1, pages 403-463.
    Elsevier, Amsterdam (1995).

  • F. Jülicher, U. Seifert, and R. Lipowsky.
    Phase diagrams and shape transformations of toroidal vesicles.
    J. Phys. II France 3 , 1681-1705 (1993).

  • F. Jülicher, U. Seifert, and R. Lipowsky.
    Conformal degeneracy and conformal diffusion of vesicles.
    Phys. Rev. Lett. 71 , 452-455 (1993).

  • F. Jülicher and R. Lipowsky.
    Domain-induced budding of vesicles.
    Phys. Rev. Lett. 70, 2964-2967 (1993).

  • U. Seifert and R. Lipowsky.
    Adhesion and unbinding of vesicles.
    In D. Beysens and N. Boccara and G. Forgacs, editors,
    ''Dynamical phenomena at interfaces, surfaces, and membranes'', pages 295-304.
    Nova Science, New York (1993).

  • R. Lipowsky.
    Domain-induced budding of fluid membranes.
    Biophys. J. 64 , 1133-1138 (1993). PDF (476 KB)

  • S. Komura and R. Lipowsky.
    Fluctuations and stability of polymerized vesicles.
    J. Phys. II France 2 , 1563-1575 (1992).

  • R. Lipowsky.
    Budding of membranes induced by intramembrane domains
    J. Phys. II France 2 , 1825-1840 (1992).

  • U. Seifert, K. Berndl, and R. Lipowsky.
    Shape transformations of vesicles: phase diagram for spontaneous curvature and bilayer coupling model.
    Phys. Rev. A 44 , 1182-1202 (1991).

  • R. Lipowsky and U. Seifert.
    Adhesion of vesicles and membranes.
    Mol. Cryst. Liq. Cryst. 202 , 17-25 (1991).

  • R. Lipowsky.
    The conformation of membranes.
    Nature 349 , 475-481 (1991).

  • R. Lipowsky and U. Seifert.
    Adhesion of membranes: a theoretical perspective.
    Langmuir 7 , 1867-1873 (1991).

  • K. Berndl, J. Käs, R. Lipowsky, E. Sackmann, and U. Seifert.
    Shape transformations of giant vesicles: extreme sensitivity to bilayer asymmetry
    Europhys. Lett. 13 , 659-664 (1990).

  • U. Seifert and R. Lipowsky.
    Adhesion of vesicles.
    Phys. Rev. A 42 , 4768-4771 (1990).