Publications

Langhans, A.; Krummhaar, M.; Roth, C.; Koksch, B.: Catalytically competent fluorinated barnase variants. Synlett 35 (9), pp. 1042 - 1046 (2024)

Polewski, L.; Moon, E.; Zappe, A.; Götze, M.; Szekeres, G. P.; Roth, C.; Pagel, K.: Ion mobility mass spectrometry-based disaccharide analysis of glycosaminoglycans. Chemistry – A European Journal 30 (36), e202400783 (2024)

Baryzewska, A.; Roth, C.; Seeberger, P. H.; Zeininger, L.: In situ tracking of exoenzyme activity using droplet luminescence concentrators for ratiometric detection of bacteria. ACS Sensors 8 (11), pp. 4143 - 4151 (2023)

Zhang, Z.; Dong, M.; Zallot, R.; Blackburn, G. M.; Wang, N.; Wang, C.; Chen, L.; Baumann, P.; Wu, Z.; Wang, Z. et al.; Fan, H.; Roth, C.; Jin, Y.; He, Y.: Mechanistic and structural insights into the specificity and biological functions of bacterial sulfoglycosidases. ACS Catalysis 13 (1), pp. 824 - 836 (2023)

Huhmann, S.; Nyakatura, E.; Rohrhofer, A.; Moschner, J.; Schmidt, B.; Eichler, J.; Roth, C.; Koksch, B.: Systematic evaluation of fluorination as modification for peptide-based fusion inhibitors against HIV-1 infection. Chembiochem 22 (24), pp. 3443 - 3451 (2021)

Thota, C. K.; Mikolajczak, D. J.; Roth, C.; Koksch, B.: Enhancing antimicrobial peptide potency through multivalent presentation on coiled-coil nanofibrils. ACS Medicinal Chemistry Letters 12 (1), pp. 67 - 73 (2021)

Cresser-Brown, J.; Rizkallah, P.; Jin, Y.; Roth, C.; Miller, D. J.; Allemann, R. K.: An unexpected co-crystal structure of the calpain PEF(S) domain with Hfq reveals a potential chaperone function of Hfq. Acta Crystallographica Section F: Structural Biology and Crystallization Communications 76 (2), pp. 81 - 85 (2020)

Smith, P. J.; Ortiz-Soto, M. E.; Roth, C.; Barnes, W. J.; Seibel, J.; Urbanowicz, B. R.; Pfrengle, F.: Enzymatic synthesis of artificial polysaccharides. ACS Sustainable Chemistry & Engineering 8 (32), pp. 11853 - 11871 (2020)

Thota, C. K.; Berger, A. A.; Harms, B.; Seidel, M.; Böttcher, C.; von Berlepsch, H.; Xie, C.; Süssmuth, R.; Roth, C.; Koksch, B.: Short self‐assembling cationic antimicrobial peptide mimetics based on a 3,5‐diaminobenzoic acid scaffold. Peptide Sciences 112 (1), e24130 (2020)

Roth, C.; Moroz, O. V.; Turkenburg, J. P.; Blagova, E.; Waterman, J.; Ariza, A.; Ming, L.; Tianqi, S.; Andersen, C.; Davies, G. J. et al.; Wilson, K. S.: Structural and functional characterization of three novel fungal amylases with enhanced stability and pH tolerance. International Journal of Molecular Sciences 20 (19), 4902 (2019)

Potterton, L.; Agirre, J.; Ballard, C.; Cowtan, K.; Dodson, E.; Evans, P. R.; Jenkins, H. T.; Keegan, R.; Krissinel, E.; Stevenson, K. et al.; Lebedev, A.; McNicholas, S. J.; Nicholls, R. A.; Noble, M.; Pannu, N. S.; Roth, C.; Sheldrick, G.; Skubak, P.; Turkenburg, J.; Uski, V.; von Delft, F.; Waterman, D.; Wilson, K.; Winn, M.; Wojdyr, M.: CCP4i2: the new graphical user interface to the CCP4 program suite. Acta Crystallographica Section D: Structural Biology 74 (2), pp. 68 - 84 (2018)

Roth, C.; Moroz, O. V.; Ariza, A.; Skov, L. K.; Ayabe, K.; Davies, G. J.; Wilson, K. S.: Structural insight into industrially relevant glucoamylases: flexible positions of starch-binding domains. Acta Crystallographica Section D: Structural Biology 74 (5), pp. 463 - 470 (2018)

Roth, C.; Chan, S.; Offen, W. A.; Hemsworth, G. R.; Willems, L. I.; King, D. T.; Varghese, V.; Britton, R.; Vocadlo, D. J.; Davies, G. J.: Structural and functional insight into human O-GlcNAcase. Nature Chemical Biology 13 (6), pp. 610 - 612 (2017)

Roth, C.; Weizenmann, N.; Bexten, N.; Saenger, W.; Zimmermann, W.; Maier, T.; Sträter, N.: Amylose recognition and ring-size determination of amylomaltase. Science Advances 3 (1), e1601386 (2017)

Roth, C.; Petricevic, M.; John, A.; Goddard-Borger, E. D.; Davies, G. J.; Williams, S. J.: Structural and mechanistic insights into a Bacteroides vulgatus retaining N-acetyl-β-galactosaminidase that uses neighbouring group participation. Chemical Communications 52 (74), pp. 11096 - 11099 (2016)

Roth, C.; Wei, R.; Oeser, T.; Then, J.; Föllner, C.; Zimmermann, W.; Sträter, N.: Structural and functional studies on a thermostable polyethylene terephthalate degrading hydrolase from Thermobifida fusca. Applied Microbiology and Biotechnology 98 (18), pp. 7815 - 7823 (2014)

Darby, J. F.; Landström, J.; Roth, C.; He, Y.; Davies, G. J.; Hubbard, R. E.: Discovery of Selective Small-Molecule Activators of a Bacterial Glycoside Hydrolase. Angewandte Chemie International Edition 53 (49), pp. 13419 - 13423 (2014)

He, Y.; Roth, C.; Turkenburg, J. P.; Davies, G. J.: Three-dimensional structure of a Streptomyces sviceus GNAT acetyltransferase with similarity to the C-terminal domain of the human GH84 O-GlcNAcase. Acta Crystallographica Section D 70 (1), pp. 186 - 195 (2014)

Dahms, S. O.; Kuester, M.; Streb, C.; Roth, C.; Sträter, N.; Than, M. E.: Localization and orientation of heavy-atom cluster compounds in protein crystals using molecular replacement. Acta Crystallographica Section D 69 (2), pp. 284 - 297 (2013)

Roth, C.; Gröning, J. A. D.; Kaschabek, S. R.; Schlömann, M.; Sträter, N.: Crystal structure and catalytic mechanism of chloromuconolactone dehalogenase ClcF from Rhodococcus opacus 1CP. Molecular Microbiology 88 (2), pp. 254 - 267 (2013)