Efficient continuous flow synthesis of the anti-malarial drug artemisinin

Research report (imported) 2011 - Max Planck Institute of Colloids and Interfaces

Authors
Kopetzki, Daniel
Departments
Biomolekulare Systeme (Prof. Dr. Peter H. Seeberger)
Summary
With nearly 1 million people dying per year, malaria is a global health problem. Artemisinin combination therapies are regarded as first-line drugs. However, their supply is limited, as artemisinin is currently solely extracted from plants. Its precursor dihydroartemisinic acid on the other hand can be obtained by a biotechnological process. A continuous flow chemistry setup was developed to produce artemisinin from this precursor in high yield just using oxygen and light.

For the full text, see the German version.

Go to Editor View