Kwon, Y.; Liu, X.; Seeberger, P. H.: Total syntheses of fully lipidated glycosylphosphatidylinositol anchors of Toxoplasma gondii. Chemical Communications (17), pp. 2280 - 2282 (2005)
Kwon, Y.-U.; Soucy, R. L.; Snyder, D. A.; Seeberger, P. H.: Assembly of a series of malarial glycosylphosphatidylinositol anchor oligosaccharides. Chemistry – A European Journal 11 (8), pp. 2493 - 2504 (2005)
Liu, X.; Kwon, Y.-U.; Seeberger, P. H.: Convergent synthesis of a fully lipidated glycosylphosphatidylinositol anchor of Plasmodium falciparum. Journal of the American Chemical Society 127 (14), pp. 5004 - 5005 (2005)
Love, K. R.; Seeberger, P. H.: Solution syntheses of protected type II Lewis blood group oligosaccharides : study for automated synthesis. The Journal of Organic Chemistry 70 (8), pp. 3168 - 3177 (2005)
Nokami, T.; Werz, D.; Seeberger, P. H.: Synthesis and reactions of 1,4-anhydrogalactopyranose and 1,4-anhydroarabinose - Steric and electronic limitations. Helvetica Chimica Acta 88 (11), pp. 2823 - 2831 (2005)
Ramasamy, V.; Ramakrishnan, B.; Boeggeman, E.; Ratner, D. M.; Seeberger, P. H.; Qasba, P. K.: Oligosaccharide preferences of β1,4-galactosyltransferase-I: crystal structures of Met340His mutant of human β1,4-galactosyltransferase-I with a pentasaccharide and trisaccharides of the N-glycan moiety. Journal of Molecular Biology (London) 353 (1), pp. 53 - 67 (2005)
Ratner, D.; Murphy, E.; Jhunjhunwala, M.; Snyder, D.; Jensen, K.; Seeberger, P. H.: Microreactor-based reaction optimization in organic chemistry glycosylation as a challenge. Chemical Communications (5), pp. 578 - 580 (2005)
Seeberger, P. H.: Automated assembly of oligosaccharides: from a platform technology to applications. Chimica Oggi-Chemistry Today 23, pp. 16 - 19 (2005)
Timmer, M.; Adibekian, A.; Seeberger, P. H.: Short de novo synthesis of fully functionalized uronic acid monosaccharides. Angewandte Chemie International Edition 44 (46), pp. 7605 - 7607 (2005)
Werz, D.; Seeberger, P. H.: Total synthesis of antigen Bacillus anthracis tetrasaccharide - Creation of an anthrax vaccine candidate. Angewandte Chemie International Edition 44 (39), pp. 6315 - 6318 (2005)
Werz, D. B.; Seeberger, P. H.: Carbohydrates as the next frontier in pharmaceutical research. Chemistry – A European Journal 11 (11), pp. 3194 - 3206 (2005)
Adams, E. W.; Ratner, D. M.; Bokesch, H. R.; McMahon, J. B.; O'Keefe, B. R.; Seeberger, P. H.: Oligosaccharide and glycoprotein microarrays as tools in HIV glycobiology: glycan-dependent gp120/protein interactions. Chemistry & Biology 11 (6), pp. 875 - 881 (2004)
Disney, M.; Magnet, S.; Blanchard, J.; Seeberger, P. H.: Aminoglycoside microarrays to study antibiotic resistance. Angewandte Chemie International Edition 43 (12), pp. 1591 - 1594 (2004)
Disney, M. D.; Seeberger, P. H.: Aminoglycoside microarrays to explore interactions of antibiotics with RNAs and proteins. Chemistry – A European Journal 10 (13), pp. 3308 - 3314 (2004)
Disney, M. D.; Seeberger, P. H.: The use of carbohydrate microarrays to study carbohydrate-cell interactions and to detect pathogens. Chemistry & Biology 11 (12), pp. 1701 - 1707 (2004)
Disney, M. D.; Zheng, J.; Swager, T. M.; Seeberger, P. H.: Detection of bacteria with carbohydrate-functionalized fluorescent polymers. Journal of the American Chemical Society 126 (41), pp. 13343 - 13346 (2004)
Hölemann, A.; Seeberger, P. H.: Carbohydrate diversity: synthesis of glycoconjugates and complex carbohydrates. Current Opinion in Biotechnology 15 (6), pp. 615 - 622 (2004)
The Department of Sustainable and Bio-Inspired Materials (SBM) was one of 24 teams selected from over 270 applicants for the Best Research Environment Award, launched in 2024 by Die Junge Akademie and the Volkswagen Foundation.
We left the lab coat hanging for a day—but brought our lab equipment with us to meet more than 8,200 visitors. At our 10 stations, we showcased how we learn from nature to develop sustainable solutions—from dye- and pigment-free colors to bio-inspired materials for construction, medicine, and design.
Challenge: It's not just whether a membrane is in a "solid" or "liquid" state that matters—how tightly its molecules are packed also influences how protein-rich droplets (condensates) stick to it Finding: More tightly packed membranes push away condensates, while loosely packed ones attract them Impact: Understanding these interactions is key to grasping essential cellular functions and disease progression
Supported by the EU’s Marie Skłodowska-Curie Actions and the UK Guarantee Scheme, the 'Condensates at Membrane Scaffolds – Integrated Systems as Synthetic Cell Compartments’ doctoral network seeks 17 PhD candidates. This international and interdisciplinary program aims to train future biomedical and biotechnology researchers to explore cellular…
Scientists can now predict structural colors in bacteria. By sequencing a wide range of bacterial DNA and developing an accurate predictive model, reseachers uncovered how bacteria organize themselves into specific patterns within colonies to interfere with light and create iridescence.Their findings hold great promise for sustainable, pigment-free color production.
Imagine switching on a light and being able to understand and control the inner dynamics of a cell. This is what the Dimova group has achieved: by shining lights of different colors on replicates of cells, they altered the interactions between cellular elements. Controlling these complex interactions enables us to deliver specific drugs directly into the cells.
Little is known yet about the interaction between these biomolecular condensate droplets and the membrane-bound organelles. Researchers at the Max Planck Institute of Colloids and Interfaces in Potsdam developed synthetic membraneless organelles and visualized what happens when they meet a membrane.
Prof Silvia Vignolini, Ph.D. is establishing the new Department "Sustainable and Bio-inspired Materials". She is working at the interface of physics, chemistry, biology and materials science and perfectly complements the institute's profile of research on chemistry, materials and sustainability.