Selected Publications

Danglad-Flores, J. A.; Leichnitz, S.; Sletten, E. T.; Joseph, A. A. S.; Bienert, K.; Le Mai Hoang, K.; Seeberger, P. H.: Microwave-assisted automated glycan assembly. Journal of the American Chemical Society 143 (23), pp. 8893 - 8901 (2021)

Joseph, A. A. S.; Pardo-Vargas, A.; Seeberger, P. H.: Total synthesis of polysaccharides by automated glycan assembly. Journal of the American Chemical Society 142 (19), pp. 8561 - 8564 (2020)

Le Mai Hoang, K.; Pardo-Vargas, A.; Zhu, Y.; Yu, Y.; Loria, M.; Delbianco, M.; Seeberger, P. H.: Traceless photolabile linker expedites chemical synthesis of complex oligosaccharides by automated glycan assembly. Journal of the American Chemical Society 141 (22), pp. 9079 - 9086 (2019)

Hahm, H. S.; Schlegel, M. K.; Hurevich, M.; Eller, S.; Schuhmacher, F.; Hofmann, J.; Pagel, K.; Seeberger, P. H.: Automated glycan assembly using the Glyconeer 2.1 synthesizer. Proceedings of the National Academy of Sciences of the USA 114 (17), pp. E3385 - E3389 (2017)

Seeberger, P. H.; Tuck, O. T.; Sletten, E. T.; Danglad-Flores, J. A.: Towards a systematic understanding of the influence of temperature on glycosylation reactions. Angewandte Chemie International Edition 61 (15), e202115433 (2022)

Moon, S.-Y.; Chatterjee, S.; Seeberger, P. H.; Gilmore, K.: Predicting glycosylation stereoselectivity using machine learning. Chemical Science 12 (8), pp. 2931 - 2939 (2021)

Chatterjee, S.; Moon, S.; Hentschel, F.; Gilmore, K.; Seeberger, P. H.: An empirical understanding of the glycosylation reaction. Journal of the American Chemical Society 140 (38), pp. 11942 - 11953 (2018)

Sianturi, J.; Priegue, P.; Hu, J.; Yin, J.; Seeberger, P. H.: Semi-synthetic glycoconjugate vaccine lead against Acinetobacter baumannii 17978. Angewandte Chemie International Edition 61 (41), e202209556 (2022)

Zhang, S.; Sella, M.; Sianturi, J.; Priegue, P.; Shen, D.; Seeberger, P. H.: Discovery of oligosaccharide antigens for semi-synthetic glycoconjugate vaccine leads against Streptococcus suis serotypes 2, 3, 9 and 14. Angewandte Chemie International Edition 60 (26), pp. 14679 - 14692 (2021)

Kaplonek, P.; Khan, N.; Reppe, K.; Schumann, B.; Emmadi, M.; Lisboa, M. P.; Xu, F.-F.; Calow, A. D. J.; Parameswarappa, S. G.; Witzenrath, M. et al.; Pereira, C. L.; Seeberger, P. H.: Improving vaccines against Streptococcus pneumoniae using synthetic glycans. Proceedings of the National Academy of Sciences of the United States of America 115 (52), pp. 13353 - 13358 (2018)

Seeberger, P. H.; Pereira, C. L.; Khan, N.; Xiao, G.; Diago-Navarro, E.; Reppe, K.; Opitz, B.; Fries, B. C.; Witzenrath, M.: A semi-synthetic glycoconjugate vaccine candidate for carbapenem-resistant Klebsiella pneumoniae. Angewandte Chemie International Edition 56 (45), pp. 13973 - 13978 (2017)

Schumann, B.; Hahm, H. S.; Parameswarappa, S. G.; Reppe, K.; Wahlbrink, A.; Govindan, S.; Kaplonek, P.; Pirofski, L.-a.; Witzenrath, M.; Chakkumkal, A. et al.; Pereira, C. L.; Seeberger, P. H.: A semisynthetic Streptococcus pneumoniae serotype 8 glycoconjugate vaccine. Science Translational Medicine 9 (380), eaaf5347 (2017)

Cavallari, M.; Stallforth, P.; Kalinichenko, A.; Rathwell, D. C. K.; Gronewold, T. M. A.; Adibekian, A.; Mori, L.; Landmann, R.; Seeberger, P. H.; De Libero, G.: A semisynthetic carbohydrate-lipid vaccine that protects against S-pneumoniae in mice. Nature Chemical Biology 10 (11), pp. 950 - 956 (2014)

Chatterjee, S.; Guidi, M.; Seeberger, P. H.; Gilmore, K.: Automated radial synthesis of organic molecules. Nature 579 (7799), pp. 379 - 384 (2020)

Triemer, S.; Gilmore, K.; Vu, G. T.; Seeberger, P. H.; Seidel-Morgenstern, A.: Literally green chemical synthesis of artemisinin from plant extracts. Angewandte Chemie International Edition 57 (19), pp. 5525 - 5528 (2018)

Ghislieri, D.; Gilmore, K.; Seeberger, P. H.: Chemical assembly systems: layered control for divergent, continuous, multistep syntheses of active pharmaceutical ingredients. Angewandte Chemie International Edition 54 (2), pp. 678 - 682 (2015)

Levesque, F.; Seeberger, P. H.: Continuous-flow synthesis of the anti-malaria drug artemisinin. Angewandte Chemie International Edition 51 (7), pp. 1706 - 1709 (2012)

Fittolani, G.; Vargová, D.; Seeberger, P. H.; Ogawa, Y.; Delbianco, M.: Bottom-up approach to understand chirality transfer across scales in cellulose assemblies. Journal of the American Chemical Society 144 (27), pp. 12469 - 12475 (2022)

Wu, X.; Delbianco, M.; Anggara, K.; Michnowicz, T.; Pardo-Vargas, A.; Bharate, P.; Sen, S.; Pristl, M.; Rauschenbach, S.; Schlickum, U. et al.; Abb, S.; Seeberger, P. H.; Kern, K.: Imaging single glycans. Nature 582 (7812), pp. 375 - 378 (2020)

Yu, Y.; Tyrikos-Ergas, T.; Zhu, Y.; Fittolani, G.; Bordoni, V.; Singhal, A.; Fair, R. J.; Grafmüller, A.; Seeberger, P. H.; Delbianco, M.: Systematic hydrogen-bond manipulations to establish polysaccharide structure–property correlations. Angewandte Chemie International Edition 58 (37), pp. 13127 - 13132 (2019)

Delbianco, M.; Kononov, A.; Poveda, A.; Yu, Y.; Diercks, T.; Jiménez-Barbero, J.; Seeberger, P. H.: Well-defined oligo- and polysaccharides as ideal probes for structural studies. Journal of the American Chemical Society 140 (16), pp. 5421 - 5426 (2018)

Qi, Z.; Bharate, P.; Lai, C.-H.; Ziem, B.; Böttcher, C.; Schulz, A.; Beckert, F.; Hatting, B.; Mülhaupt, R.; Seeberger, P. H. et al.; Haag, R.: Multivalency at interfaces: supramolecular carbohydrate-functionalized graphene derivatives for bacterial capture, release, and disinfection. Nano Letters 15 (9), pp. 6051 - 6057 (2015)

Roderer, D.; Bröcker, F.; Sitsel, O.; Kaplonek, P.; Leidreiter, F.; Seeberger, P. H.; Raunser, S.: Glycan-dependent cell adhesion mechanism of Tc toxins. Nature Communications 11, 2694 (2020)

Mucha, E.; Marianski, M.; Xu, F.-F.; Thomas, D. A.; Meijer, G.; von Helden, G.; Seeberger, P. H.; Pagel, K.: Unravelling the structure of glycosyl cations via cold-ion infrared spectroscopy. Nature Communications 9, 4174 (2018)

Gustafsen, C.; Olsen, D.; Vilstrup, J.; Lund, S.; Reinhardt, A.; Wellner, N.; Larsen, T.; Andersen, C. B.F.; Weyer, K.; Li, J.-p. et al.; Seeberger, P. H.; Thirup, S.; Madsen, P.; Glerup, S.: Heparan sulfate proteoglycans present PCSK9 to the LDL receptor. Nature Communications 8, 503 (2017)

Hofmann, J.; Hahm, H. S.; Seeberger, P. H.; Pagel, K.: Identification of carbohydrate anomers using ion mobility-mass spectrometry. Nature 526 (7572), pp. 241 - 244 (2015)

Seeberger, P. H.: Discovery of semi- and fully-synthetic carbohydrate vaccines against bacterial infections using a medicinal chemistry approach. Chemical Reviews 121 (7), pp. 3598 - 3626 (2021)

Guberman, M.; Seeberger, P. H.: Automated glycan assembly: a perspective. Journal of the American Chemical Society 141 (14), pp. 5581 - 5592 (2019)

Plutschack, M. B.; Pieber, B.; Gilmore, K.; Seeberger, P. H.: The Hitchhiker’s guide to flow chemistry. Chemical Reviews 117 (18), pp. 11796 - 11893 (2017)

Tsai, Y. H.; Liu, X.; Seeberger, P. H.: Chemical biology of glycosylphosphatidylinositol anchors. Angewandte Chemie International Edition 51 (46), pp. 11438 - 11456 (2012)