Publications

Bröcker, F.; Martin, C. E.; Wegner, E.; Mattner, J.; Baek, J. Y.; Pereira, C. L.; Chakkumkal, A.; Seeberger, P. H.: Synthetic lipoteichoic acid glycans are potential vaccine candidates to protect from Clostridium difficile infections. Cell Chemical Biology 23 (8), pp. 1014 - 1022 (2016)

Broecker, F.; Hanske, J.; Martin, C. E.; Baek, J. Y.; Wahlbrink, A.; Wojcik, F.; Hartmann, L.; Rademacher, C.; Chakkumkal, A.; Seeberger, P. H.: Multivalent display of minimal Clostridium difficile glycan epitopes mimics antigenic properties of larger glycans. Nature Communications 7, 11224 (2016)

Geißner, A.; Pereira, C. L.; Leddermann, M.; Chakkumkal, A.; Seeberger, P. H.: Deciphering antigenic determinants of Streptococcus pneumoniae serotype 4 capsular polysaccharide using synthetic oligosaccharides. ACS Chemical Biology 11 (2), pp. 335 - 344 (2016)

Geissner, A.; Seeberger, P. H.: Glycan arrays: from basic biochemical research to bioanalytical and biomedical applications. Annual Review of Analytical Chemistry 9 (1), pp. 223 - 247 (2016)

Hinneburg, H.; Stavenhagen, K.; Schweiger-Hufnagel, U.; Pengelley, S.; Jabs, W.; Seeberger, P. H.; Varón Silva, D.; Wuhrer, M.; Kolarich, D.: The art of destruction: optimizing collision energies in quadrupole-time of flight (Q-TOF) instruments for glycopeptide-based glycoproteomics. Journal of the American Society for Mass Spectrometry 27 (3), pp. 507 - 519 (2016)

Hu, J.; Seeberger, P. H.; Yin, J.: Using carbohydrate-based biomaterials as scaffolds to control human stem cell fate. Organic & Biomolecular Chemistry 14 (37), pp. 8648 - 8658 (2016)

Lee, B.-Y.; Seeberger, P. H.; Varón Silva, D.: Synthesis of glycosylphosphatidylinositol (GPI)-anchor glycolipids bearing unsaturated lipids. Chemical Communications 52 (8), pp. 1586 - 1589 (2016)

Mejia, P.; Diez-Silva, M.; Kamena, F.; Lu, F.; Fernandes, S. M.; Seeberger, P. H.; Davis III, A. E.; Mitchell, J. R.: Human C1-inhibitor suppresses malaria parasite invasion and cytoadhesion via binding to parasite glycosylphosphatidylinositol and host cell receptors. The Journal of Infectious Diseases 213 (1), pp. 80 - 89 (2016)

Möginger, U.; Resemann, A.; Martin, C. E.; Parameswarappa, S.; Govindan, S.; Wamhoff, E.-C.; Broecker, F.; Suckau, D.; Pereira, C. L.; Chakkumkal, A. et al.; Seeberger, P. H.; Kolarich, D.: Cross Reactive Material 197 glycoconjugate vaccines contain privileged conjugation sites. Scientific Reports 6, 20488 (2016)

Parameswarappa, S. G.; Reppe, K.; Geißner, A.; Ménová, P.; Govindan, S.; Calow, A. D. J.; Wahlbrink, A.; Weishaupt, M. W.; Monnanda, B. P.; Bell, R. et al.; Pirofski, L.-A.; Suttorp, N.; Sander, L.; Witzenrath, M.; Pereira, C. L.; Chakkumkal, A.; Seeberger, P. H.: A semi-synthetic oligosaccharide conjugate vaccine candidate confers protection against Streptococcus pneumoniae serotype 3 infection. Cell Chemical Biology 23 (11), pp. 1407 - 1416 (2016)

Reinhardt, A.; Wehle, M.; Geißner, A.; Crouch, E. C.; Kang, Y.; Yang, Y.; Chakkumkal, A.; Santer, M.; Seeberger, P. H.: Structure binding relationship of human surfactant protein D and various lipopolysaccharide inner core structures. Journal of Structural Biology 195 (3), pp. 387 - 395 (2016)

Schumann, B.; Parameswarappa, S.; Lisboa, M. P.; Kottari, N.; Guidetti, F.; Pereira, C. L.; Seeberger, P. H.: Nucleophile-directed stereocontrol over glycosylations using geminal-difluorinated nucleophiles. Angewandte Chemie International Edition 55 (46), pp. 14431 - 14434 (2016)

Weishaupt, M. W.; Matthies, S.; Hurevich, M.; Pereira, C. L.; Hahm, H. S.; Seeberger, P. H.: Automated glycan assembly of a S. pneumoniae serotype 3 CPS antigen. Beilstein Journal of Organic Chemistry 12, pp. 1440 - 1446 (2016)

Wörmann, X.; Lesch, M.; Welke, R.-W.; Okonechnikov, K.; Abdurishid, M.; Sieben, C.; Geißner, A.; Brinkmann, V.; Kastner, M.; Karner, A. et al.; Zhu, R.; Hinterdorfer, P.; Chakkumkal, A.; Seeberger, P. H.; Herrmann, A.; Meyer, T. F.; Karlas, A.: Genetic characterization of an adapted pandemic 2009 H1N1 influenza virus that reveals improved replication rates in human lung epithelial cells. Virology 492, pp. 118 - 129 (2016)

Zhang, Q.; Cai, Y.; Wang, X.-J.; Xu, J.-L.; Ye, Z.; Wang, S.; Seeberger, P. H.; Yin, J.: Targeted photodynamic killing of breast cancer cells employing heptamannosylated β-cyclodextrin-mediated nanoparticle formation of an adamantane-functionalized BODIPY photosensitizer. ACS Applied Materials and Interfaces 8 (49), pp. 33405 - 33411 (2016)

Schumann, B.; Reppe, K.; Hahm, H. S.; Parameswarappa, S. G.; Wahlbrink, A.; Govindan, S.; Witzenrath, M.; Chakkumkal, A.; Pereira, C. L.; Seeberger, P. H.: Passive Immunisierung mit dem monoklonalen Antikörper 1H8 schützt Mäuse vor pneumogener Sepsis. In Pneumologie, 70 (S 01), P489. 57. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V., Leipzig, March 02, 2016 - March 05, 2016. (2016)

Chakkumkal, A.; Lisboa, M.; Martin, C. E.; Pereira, C. L.; Seeberger, P. H.; Khan, N.: Vaccines against Streptococcus pneumoniae serotype 5. WO2016198170 (2016)

Seeberger, P. H.; Pereira, C. L.; Xiao, G.; Khan, N.; Chakkumkal, A.: Vaccine against carbapenem-resistant klebsiella pneumoniae. EP3274358 (2016)

Seeberger, P. H.; Pereira, C. L.; Chakkumkal, A.; Geißner, A.: Vaccines against Streptococcus pneumoniae serotype 4. EP3230297 (2016)

Seeberger, P. H.; Martin, C. E.; Bröcker, F.; Chakkumkal, A.: Antibodies for prevention and treatment of diseases caused by Clostridium difficile. (2016)