Scientific Publications of the Institute

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Journal Article (6)

2013
Journal Article
Witt, R. M.; Hecht, M. L.; Pazyra-Murphy, M. F.; Cohen, S. M.; Noti, C.; van Kuppevelt, T. H.; Fuller, M.; Chan, J. A.; Hopwood, J. J.; Seeberger, P. H. et al.; Segal, R. A.: Heparan sulfate proteoglycans containing a glypican 5 core and 2-O-sulfo-iduronic acid function as Sonic Hedgehog co-receptors to promote proliferation. Journal of Biological Chemistry 288 (36), pp. 26275 - 26288 (2013)
2011
Journal Article
Adibekian, A.; Stallforth, P.; Hecht, M. L.; Werz, D. B.; Gagneux, P.; Seeberger, P. H.: Comparative bioinformatics analysis of the mammalian and bacterial glycomes. Chemical Science 2 (2), pp. 337 - 344 (2011)
Journal Article
Horlacher, T.; Noti, C.; de Paz, J. L.; Bindschädler, P.; Hecht, M. L.; Smith, D. F.; Fukuda, M. N.; Seeberger, P. H.: Characterization of annexin A1 glycan binding reveals binding to highly sulfated glycans with preference for highly sulfated heparan sulfate and heparin. Biochemistry 50 (13), pp. 2650 - 2659 (2011)
Journal Article
Oberli, M. A.; Hecht, M. L.; Bindschädler, P.; Adibekian, A.; Adam, T.; Seeberger, P. H.: A possible oligosaccharide-conjugate vaccine candidate for Clostridium difficile is antigenic and immunogenic. Chemistry & Biology 18 (5), pp. 580 - 588 (2011)
2010
Journal Article
Hecht, M. L.; Tsai, Y. H.; Liu, X. Y.; Wolfrum, C.; Seeberger, P. H.: Synthetic inositol phosphoglycans related to GPI lack insulin-mimetic activity. ACS Chemical Biology 5 (11), pp. 1075 - 1086 (2010)
2009
Journal Article
Hecht, M. L.; Stallforth, P.; Varón Silva, D.; Adibekian, A.; Seeberger, P. H.: Recent advances in carbohydrate-based vaccines. Current Opinion in Chemical Biology 13 (3), pp. 354 - 359 (2009)

Thesis - PhD (1)

2010
Thesis - PhD
Hecht, M.-L.: Structure-activity relationships of complex carbohydrates. Dissertation, ETH, Zürich (2010)

Patent (1)

2012
Patent
Seeberger, P. H.; Oberli, M.; Hecht, M.-L.: Oligosaccharides and oligosaccharide-protein conjugates derived from clostridium difficile polysaccharide PS-II, methods of synthesis and uses thereof, in particular as a vaccine. EP2683401 (2012)
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