Dasgupta, R.; Miettinen, M. S.; Fricke, N.; Lipowsky, R.; Dimova, R.: The glycolipid GM1 reshapes asymmetric biomembranes and giant vesicles by curvature generation. Proceedings of the National Academy of Sciences of the United States of America 115 (22), pp. 5756 - 5761 (2018)
Fricke, N.; Dimova, R.: GM1 softens POPC membranes and induces the formation of micron-sized domains. Biophysical Journal 111 (9), pp. 1935 - 1945 (2016)
Fricke, N.; Dimova, R.: How GM1 Affects the Phase State and Mechanical Properties of Phospholipid Membranes. Biophysical Journal (Annual Meeting Abstracts) 108 (2), p. 18A - 18A (2015)
Fricke, N.: Eine Riesenvesikel-Studie zum Einfluss des Glycolipids GM1 auf Phospholipid-Membranen. Dissertation, 117 pp., Universität Potsdam, Potsdam (2012)
We left the lab coat hanging for a day—but brought our lab equipment with us to meet more than 8,200 visitors. At our 10 stations, we showcased how we learn from nature to develop sustainable solutions—from dye- and pigment-free colors to bio-inspired materials for construction, medicine, and design.
Challenge: It's not just whether a membrane is in a "solid" or "liquid" state that matters—how tightly its molecules are packed also influences how protein-rich droplets (condensates) stick to it Finding: More tightly packed membranes push away condensates, while loosely packed ones attract them Impact: Understanding these interactions is key to grasping essential cellular functions and disease progression
Supported by the EU’s Marie Skłodowska-Curie Actions and the UK Guarantee Scheme, the 'Condensates at Membrane Scaffolds – Integrated Systems as Synthetic Cell Compartments’ doctoral network seeks 17 PhD candidates. This international and interdisciplinary program aims to train future biomedical and biotechnology researchers to explore cellular…
Scientists can now predict structural colors in bacteria. By sequencing a wide range of bacterial DNA and developing an accurate predictive model, reseachers uncovered how bacteria organize themselves into specific patterns within colonies to interfere with light and create iridescence.Their findings hold great promise for sustainable, pigment-free color production.
Imagine switching on a light and being able to understand and control the inner dynamics of a cell. This is what the Dimova group has achieved: by shining lights of different colors on replicates of cells, they altered the interactions between cellular elements. Controlling these complex interactions enables us to deliver specific drugs directly into the cells.
Little is known yet about the interaction between these biomolecular condensate droplets and the membrane-bound organelles. Researchers at the Max Planck Institute of Colloids and Interfaces in Potsdam developed synthetic membraneless organelles and visualized what happens when they meet a membrane.
Prof Silvia Vignolini, Ph.D. is establishing the new Department "Sustainable and Bio-inspired Materials". She is working at the interface of physics, chemistry, biology and materials science and perfectly complements the institute's profile of research on chemistry, materials and sustainability.