Barandov, A.; Grünstein, D.; Apostolova, I.; Buchert, R.; Roger, M.; Brenner, W.; Abram, U.; Seeberger, P. H.: A new bifunctional chelator enables facile biocoupling and radiolabeling as the basis for a bioconjugation kit. ChemBioChem: A European Journal of Chemical Biology 15 (7), pp. 986 - 994 (2014)
Kennedy, D. C.; Grünstein, D.; Lai, C. H.; Seeberger, P. H.: Glycosylated nanoscale surfaces: preparation and applications in medicine and molecular Biology. Chemistry – A European Journal 19 (12), pp. 3794 - 3800 (2013)
Barylyuk, K.; Balabin, R. M.; Grünstein, D.; Kikkeri, R.; Frankevich, V.; Seeberger, P. H.; Zenobi, R.: What happens to hydrophobic interactions during transfer from the solution to the gas phase? The case of electrospray-based soft ionization methods. Journal of the American Society for Mass Spectrometry 22 (7), pp. 1167 - 1177 (2011)
Kikkeri, R.; Grünstein, D.; Seeberger, P. H.: Lectin biosensing using digital analysis of Ru(II)-glycodendrimers. Journal of the American Chemical Society 132 (30), pp. 10230 - 10232 (2010)
Kikkeri, R.; Hong, S. Y.; Grünstein, D.; Laurino, P.; Seeberger, P. H.: Carbohydrate-based nanoscience: metallo-glycodendrimers and quantum dots as multivalent probes. In: Proceedings of the International Beilstein Symposium on Functional Nanoscience, pp. 143 - 166 (Eds. Hicks, M. G.; Kettner, C.). Logos-Verlag, Berlin (2011)
Grünstein, D.: Carbohydrate systems for biosensing, imaging, and medical applications. Dissertation, getr. Pag. pp., Freie Universität Berlin, Berlin (2012)
Supported by the EU’s Marie Skłodowska-Curie Actions and the UK Guarantee Scheme, the 'Condensates at Membrane Scaffolds – Integrated Systems as Synthetic Cell Compartments’ doctoral network seeks 17 PhD candidates. This international and interdisciplinary program aims to train future biomedical and biotechnology researchers to explore cellular…
Scientists can now predict structural colors in bacteria. By sequencing a wide range of bacterial DNA and developing an accurate predictive model, reseachers uncovered how bacteria organize themselves into specific patterns within colonies to interfere with light and create iridescence.Their findings hold great promise for sustainable, pigment-free color production.
Biomolecular condensates may play a crucial but overlooked role in remodeling membrane structures within cells. Rumiana Dimova and her team demonstrated that these droplets can shape parts of the endoplasmic reticulum into nanotubes and double-membrane discs without the need for specific curvature-molding proteins.
Imagine switching on a light and being able to understand and control the inner dynamics of a cell. This is what the Dimova group has achieved: by shining lights of different colors on replicates of cells, they altered the interactions between cellular elements. Controlling these complex interactions enables us to deliver specific drugs directly into the cells.
Little is known yet about the interaction between these biomolecular condensate droplets and the membrane-bound organelles. Researchers at the Max Planck Institute of Colloids and Interfaces in Potsdam developed synthetic membraneless organelles and visualized what happens when they meet a membrane.
Prof Silvia Vignolini, Ph.D. is establishing the new Department "Sustainable and Bio-inspired Materials". She is working at the interface of physics, chemistry, biology and materials science and perfectly complements the institute's profile of research on chemistry, materials and sustainability.