Publications

Zeitschriftenartikel (202)

1.
Zeitschriftenartikel
Omoregbee-Leichnitz, S.; Reuber, E.; Weber, F.; Stolte, K. N.; Danglad-Flores, J.; Dommisch, H.; Seeberger, P. H.: Automated glycan assembly of Porphyromonas gingivalis lipopolysaccharide epitopes for vaccine design. Journal of the American Chemical Society (2025)
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2.
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Michel, M.; Stijlemans, B.; Michel, D.; Garg, M.; Geißner, A.; Seeberger, P. H.; Varón Silva, D.: Detection of antibodies against the African parasite Trypanosoma brucei using synthetic glycosylphosphatidylinositol oligosaccharide fragments. Glycoconjugate Journal (2025)
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3.
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Chen, G.; Tian, G.; Hu, J.; Qin, C.; Zou, X.; Cai, J.; Lv, G.; Gao, W.; Seeberger, P. H.; Yin, J.: Chemical synthesis elucidates the absolute configuration and key antigenic epitope of Vibrio cholerae serotype O100 O-antigen. Science Advances 11 (17), eadv0571 (2025)
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4.
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Pradhan, K.; Reuber, E.; Sletten, E. T.; Tomaso, H.; Seeberger, P. H.: A synthetic oligosaccharide resembling Francisella tularensis strain 15 O-antigen capsular polysaccharide as a lead for tularemia diagnostics and therapeutics. Angewandte Chemie International Edition 64 (4), e202416432 (2025)
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5.
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Qin, C.; Han, W.; Tian, G.; Zou, X.; Maciejewska, A.; Lukasiewicz, J.; Seeberger, P. H.; Hu, J.; Yin, J.: Antigenicity evaluation of the synthetic trisaccharides related to Plesiomonas shigelloides serotype O51 O-antigen containing an acetamidino group. Carbohydrate Research 550, 109388 (2025)
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6.
Zeitschriftenartikel
Sianturi, J.; Weber, F.; Singh, R. K.; Lingscheid, T.; Tober-Lau, P.; Kurth, F.; Fries, B. C.; Seeberger, P. H.: Klebsiella pneumoniae Glycoconjugate Vaccine Leads Based on Semi-Synthetic O1 and O2ac Antigens. Angewandte Chemie International Edition 64 (7), e202419516 (2025)
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7.
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Chang, C.-W.; Greis, K.; Prabhu, G. R. D.; Wehner, D.; Kirschbaum, C.; Ober, K.; Torres-Boy, A. Y.; Leichnitz, S.; Meijer, G.; von Helden, G. et al.; Seeberger, P. H.; Pagel, K.: Mechanistic insight into benzylidene-directed glycosylation reactions using cryogenic infrared spectroscopy. Nature Synthesis 3 (2024)
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8.
Zeitschriftenartikel
Danglad-Flores, J. A.; Sletten, E. T.; Reuber, E.; Bienert, K.; Riegler, H.; Seeberger, P. H.: Optimized platform for automated glycan assembly. Device 2 (10), 100499 (2024)
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9.
Zeitschriftenartikel
Jordan, C.; Siebold, K.; Priegue, P.; Seeberger, P. H.; Gilmour, R.: A fluorinated sialic acid vaccine lead against meningitis B and C. Journal of the American Chemical Society 146 (22), S. 15366 - 15375 (2024)
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10.
Zeitschriftenartikel
Shen, D.; Silva Seco, B. M.; Teixeira Alves, L. G.; Yao, L.; Bräutigam, M.; Opitz, B.; Witzenrath, M.; Fries, B. C.; Seeberger, P. H.: Semisynthetic glycoconjugate vaccine lead against klebsiella pneumoniae serotype O2afg induces functional antibodies and reduces the burden of acute pneumonia. Journal of the American Chemical Society 146 (51), S. 35356 - 35366 (2024)
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11.
Zeitschriftenartikel
Standvoss, K.; Kazezian, V.; Lewke, B. R.; Bastian, K.; Chidambaram, S.; Arafat, S.; Alsharif, U.; Herrera-Melendez, A.; Knipper, A.-D.; Silva Seco, B. M. et al.; Soto, N. N.; Rakitzis, O.; Steinecker, I.; van Kronenberg Till, P.; Zarebidaki, F.; Abbasi, P.; Weissgerber, T. L.: Shortcut citations in the methods section: frequency, problems, and strategies for responsible reuse. PLOS Biology 22 (4), e3002562 (2024)
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12.
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Tian, G.; Hu, J.; Qin, C.; Li, L.; Ning, Y.; Zhu, S.; Xie, S.; Zou, X.; Seeberger, P. H.; Yin, J.: Chemical synthesis and antigenicity evaluation of an aminoglycoside trisaccharide repeating unit of Pseudomonas aeruginosa Serotype O5 O-Antigen containing a rare dimeric-ManpN3NA. Journal of the American Chemical Society 146 (27), S. 18427 - 18439 (2024)
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13.
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Wrage, M.; Holland, T.; Nüse, B.; Kaltwasser, J.; Fröhlich, J.; Arnold, H.; Gießler, C.; Flamann, C.; Bruns, H.; Berges, J. et al.; Daniel, C.; Hoffmann, M. H.; Anish, C.; Seeberger, P. H.; Bogdan, C.; Dettmer, K.; Rauh, M.; Mattner, J.: Cell type-specific modulation of metabolic, immune-regulatory, and anti-microbial pathways by CD101. Mucosal immunology, S. 892 - 910 (2024)
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14.
Zeitschriftenartikel
Zhao, M.; Tian, G.; Qin, C.; Zou, X.; Seeberger, P. H.; Hu, J.; Yin, J.: Immunological exploration of Helicobacter pylori serotype O2 O-antigen by using a synthetic glycan library. Chinese Journal of Chemistry 42 (3), S. 243 - 251 (2024)
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15.
Zeitschriftenartikel
Baryzewska, A.; Roth, C.; Seeberger, P. H.; Zeininger, L.: In situ tracking of exoenzyme activity using droplet luminescence concentrators for ratiometric detection of bacteria. ACS Sensors 8 (11), S. 4143 - 4151 (2023)
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16.
Zeitschriftenartikel
Bialangi, N.; Mustapa, M. A.; Salimi, Y.; Musa, W.; Widiyantoro, A.; Ibrahim, A. M.; Situmeang, B.; Sianturi, J.: Evaluation of the antiplasmodial properties of Andrographis paniculata (Burm.f.) and Peperomia pellucida (L.) Kunth. Indonesian Journal of Chemistry 23 (1), S. 62 - 72 (2023)
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17.
Zeitschriftenartikel
Goerdeler, F.; Reuber, E.; Lühle, J.; Leichnitz, S.; Freitag, A.; Nedielkov, R.; Groza, R.; Ewers, H.; Möller, H. M.; Seeberger, P. H. et al.; Moscovitz, O.: Thiol-mediated uptake of a cysteine-containing nanobody for anticancer drug delivery. ACS Central Science 9 (6), S. 1111 - 1118 (2023)
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18.
Zeitschriftenartikel
Kastner, M.; Karner, A.; Zhu, R.; Huang, Q.; Geißner, A.; Sadewasser, A.; Lesch, M.; Wörmann, X.; Karlas, A.; Seeberger, P. H. et al.; Wolff, T.; Hinterdorfer, P.; Herrmann, A.; Sieben, C.: Relevance of host cell surface glycan structure for cell specificity of influenza A viruses. Viruses 15 (7), 1507 (2023)
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19.
Zeitschriftenartikel
Khilji, S. K.; Op 't Hoog, C.; Warschkau, D.; Lühle, J.; Goerdeler, F.; Freitag, A.; Seeberger, P. H.; Moscovitz, O.: Smaller size packs a stronger punch: recent advances in small antibody fragments targeting tumour-associated carbohydrate antigens. Theranostics 13 (9), S. 3041 - 3063 (2023)
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20.
Zeitschriftenartikel
Lewis, A. L.; Toukach, P.; Bolton, E.; Chen, X.; Frank, M.; Lütteke, T.; Knirel, Y.; Schoenhofen, I.; Varki, A.; Vinogradov, E. et al.; Woods, R. J.; Zachara, N.; Zhang, J.; Kamerling, J. P.; Neelamegham, S.; Seeberger, P. H.; the SNFG Discussion Group: Cataloging natural sialic acids and other nonulosonic acids (NulOs), and their representation using the Symbol Nomenclature for Glycans. Glycobiology 33 (2), S. 99 - 103 (2023)
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21.
Zeitschriftenartikel
Sabbavarapu, N. M.; Seeberger, P. H.: Automated glycan assembly of mycobacterial hexaarabinofuranoside and docosasaccharide arabinan (Araf23) motifs found on mycobacterium tuberculosis. Chemistry – A European Journal 29 (23), e202300032 (2023)
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22.
Zeitschriftenartikel
Sabbavarapu, N. M.; Seeberger, P. H.: Automated glycan assembly of highly branched heptadecasaccharide repeating unit of arabinogalactan polysaccharide HH1-1 from Carthamus tinctorius. Chemical Communications 59 (32), S. 4822 - 4824 (2023)
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23.
Zeitschriftenartikel
Singh, R. K.; Reuber, E.; Bruno, M.; Netea, M. G.; Seeberger, P. H.: Synthesis of oligosaccharides to identify an immunologically active epitope against Candida auris infection. Chemical Science 14 (27), S. 7559 - 7563 (2023)
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24.
Zeitschriftenartikel
Ben Ami Pilo, H.; Khilji, S. K.; Lühle, J.; Biskup, K.; Levy Gal, B.; Rosenhek Goldian, I.; Alfandari, D.; Revach, O.-Y.; Kiper, E.; Morandi, M. I. et al.; Rotkopf, R.; Porat, Z.; Blanchard, V.; Seeberger, P. H.; Regev-Rudzki, N.; Moscovitz, O.: Sialylated N-glycans mediate monocyte uptake of extracellular vesicles secreted from Plasmodium falciparum-infected red blood cells. Journal of Extracellular Biology 1 (2), e33 (2022)
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25.
Zeitschriftenartikel
Boyraz, B.; Saatz, J.; Pompös, I.-M.; Gad, M.; Dernedde, J.; Maier, A.-K. B.; Moscovitz, O.; Seeberger, P. H.; Traub, H.; Tauber, R.: Imaging keratan sulfate in ocular tissue sections by immunofluorescence microscopy and LA-ICP-MS. ACS applied bio materials 5 (2), S. 853 - 861 (2022)
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26.
Zeitschriftenartikel
Garcia Ricardo, M.; Reuber, E.; Yao, L.; Danglad-Flores, J. Á.; Delbianco, M.; Seeberger, P. H.: Design, synthesis, and characterization of stapled oligosaccharides. Journal of the American Chemical Society 144 (40), S. 18429 - 18434 (2022)
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27.
Zeitschriftenartikel
Ghosh, C.; Priegue, P.; Leelayuwapan,, H.; Fuchsberger, F. F.; Rademacher, C.; Seeberger, P. H.: Synthetic glyconanoparticles modulate innate immunity but not the complement system. ACS applied bio materials 5 (5), S. 2185 - 2192 (2022)
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28.
Zeitschriftenartikel
Greis, K.; Leichnitz, S.; Kirschbaum, C.; Chang, C.-W.; Lin, M.-H.; Meijer, G.; von Helden, G.; Seeberger, P. H.; Pagel, K.: The influence of the electron density in acyl protecting groups on the selectivity of galactose formation. Journal of the American Chemical Society 144 (44), S. 20258 - 20266 (2022)
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29.
Zeitschriftenartikel
Kaplonek, P.; Yao, L.; Reppe, K.; Voß, F.; Kohler, T.; Ebner, F.; Schäfer, A.; Blohm, U.; Priegue, P.; Bräutigam, M. et al.; Pereira, C. L.; Parameswarappa, S. G.; Emmadi, M.; Ménová, P.; Witzenrath, M.; Hammerschmidt, S.; Hartmann, S.; Sander, L. E.; Seeberger, P. H.: A semisynthetic glycoconjugate provides expanded cross-serotype protection against Streptococcus pneumoniae. Vaccine (2022)
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pre-print
30.
Zeitschriftenartikel
Khilji, S. K.; Goerdeler, F.; Frensemeier, K.; Warschkau, D.; Lühle, J.; Fandi, Z.; Schirmeister, F.; Chen, Z. A.; Turak, O.; Mallagaray, A. et al.; Boerno, S.; Timmermann, B.; Rappsilber, J.; Seeberger, P. H.; Moscovitz, O.: Generation of glycan-specific nanobodies. Cell Chemical Biology 29 (8), S. 1353 - 1361 (2022)
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31.
Zeitschriftenartikel
Leichnitz, S.; Dissanayake, K. C.; Winter, A. H.; Seeberger, P. H.: Photo-labile BODIPY protecting groups for glycan synthesis. Chemical Communications 58 (75), S. 10556 - 10559 (2022)
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32.
Zeitschriftenartikel
Liang, C.-F.; Hahm, H. S.; Sabbavarapu, N. M.; Seeberger, P. H.: Automated synthesis of chondroitin sulfate oligosaccharides. Methods in Molecular Biology 2303, S. 319 - 327 (2022)
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33.
Zeitschriftenartikel
Qin, C.; Li, L.; Tian, G.; Ding, M.; Zhu, S.; Song, W.; Hu, J.; Seeberger, P. H.; Yin, J.: Chemical synthesis and antigenicity evaluation of Shigella dysenteriae serotype 10 O-antigen tetrasaccharide containing a (S)-4,6-O-pyruvyl ketal. Journal of the American Chemical Society 144 (46), S. 21068 - 21079 (2022)
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34.
Zeitschriftenartikel
Sianturi, J.; Priegue, P.; Hu, J.; Yin, J.; Seeberger, P. H.: Semi-synthetic glycoconjugate vaccine lead against Acinetobacter baumannii 17978. Angewandte Chemie International Edition 61 (41), e202209556 (2022)
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35.
Zeitschriftenartikel
Singh, R. K.; Sianturi, J.; Seeberger, P. H.: Synthesis of oligosaccharides resembling the Streptococcus suis serotype 18 capsular polysaccharide as a basis for glycoconjugate vaccine development. Organic Letters 24 (12), S. 2371 - 2375 (2022)
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36.
Zeitschriftenartikel
Sletten, E. T.; Danglad-Flores, J. A.; Leichnitz, S.; Joseph, A. A. S.; Seeberger, P. H.: Expedited synthesis of mannose-6-phosphate containing oligosaccharides. Carbohydrate Research 511, 108489 (2022)
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37.
Zeitschriftenartikel
Tsouka, A.; Dallabernardina, P.; Mende, M.; Sletten, E. T.; Leichnitz, S.; Bienert, K.; Le Mai Hoang, K.; Seeberger, P. H.; Löffler, F. F.: VaporSPOT: parallel synthesis of oligosaccharides on membranes. Journal of the American Chemical Society 144 (43), S. 19832 - 19837 (2022)
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38.
Zeitschriftenartikel
Wang, Y.; Menon, A. K.; Maki, Y.; Liu, Y.-S.; Iwasaki, Y.; Fujita, M.; Guerrero, P. A.; Varón Silva, D.; Seeberger, P. H.; Murakami, Y. et al.; Kinoshita, T.: Genome-wide CRISPR screen reveals CLPTM1L as a lipid scramblase required for efficient glycosylphosphatidylinositol biosynthesis. Proceedings of the National Academy of Sciences of the United States of America 119 (14), e2115083119 (2022)
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39.
Zeitschriftenartikel
Zou, X.; Hu, J.; Zhao, M.; Qin, C.; Zhu, Y.; Tian, G.; Cai, J.; Seeberger, P. H.; Yin, J.: Chemical synthesis of the highly sterically hindered core undecasaccharide of Helicobacter pylori lipopolysaccharide for antigenicity evaluation with human serum. Journal of the American Chemical Society 144 (32), S. 14535 - 14547 (2022)
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40.
Zeitschriftenartikel
Bennett, A.; Hull, J.; Jolinon, N.; Tordo, J.; Moss, K.; Binns, E.; Mietzsch, M.; Hagemann, C.; Linden, R. M.; Serio, A. et al.; Chipman, P.; Sousa, D.; Bröcker, F.; Seeberger, P. H.; Henckaerts, E.; McKenna, R.; Agbandje-McKenna, M.: Comparative structural, biophysical, and receptor binding study of true type and wild type AAV2. Journal of Structural Biology 213 (4), 107795 (2021)
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Mehr anzeigen
Martin, C. E., Broecker, F., Eller, S., Oberli, M. A., Anish, C., Pereira, C. L., Seeberger, P. H.
Glycan arrays containing synthetic Clostridium difficile lipoteichoic acid oligomers as tools toward a carbohydrate vaccine
Chem.Commun. 2013, Accepted Manuscript �
original
Martin, C. E., Broecker, F., Oberli, M. A., Komor, J., Mattner, J., Anish, C., Seeberger, P. H
Immunological Evaluation of a Synthetic Clostridium difficile Oligosaccharide Conjugate Vaccine Candidate and Identification of a Minimal Epitope
J. Am. Chem. Soc. 2013 Articles ASAP (As Soon As Publishable)
original
Yang, Y.; Oishi, S.; Martin, C. E.; Seeberger, P. H
Diversity-oriented Synthesis of Inner Core Oligosaccharides of the Lipopolysaccharide of Pathogenic Gram-negative Bacteria
J. Am. Chem. Soc. 2013, 135, 6262–6271.
Source
original
Yang, Y., C. E. Martin, Seeberger, P. H.
Total synthesis of the core tetrasaccharide of Neisseria meningitidis lipopolysaccharide, a potential vaccine candidate for meningococcal diseases
Chem. Sci. 2012, 3, 896-899.
Source
original
Martin, C. E., M. W. Weishaupt, Seeberger, P. H.
Progress toward developing a carbohydrate-conjugate vaccine against Clostridium difficile ribotype 027: synthesis of the cell-surface polysaccharide PS-I repeating unit
Chem. Commun. 2011, 47, 10260-10262.
Source
original
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