Publications

Zeitschriftenartikel (215)

Zeitschriftenartikel

Geue, N.; Greis, K.; Omoregbee-Leichnitz, S.; Kirschbaum, C.; Meijer, G.; von Helden, G.; Seeberger, P. H.; Marianski, M.; Pagel, K.: Evaluating participation modes in peracetylated glycosyl cations. Organic Letters (2026)

MPG.PuRe

DOI

pre-print

External

Zeitschriftenartikel

Kortman, H.; Fang, H.; Bastick, K. A. C.; Völkel, C.; Oberthür, D.; Seeberger, P. H.; Perbandt, M.; Molloy, J. J.: Fused 3D boron heterocycles via EnT catalysis: synthesis, modification and validation as beta-lactamase inhibitors. Chemical Science 17 (1), S. 247 - 254 (2026)

MPG.PuRe

DOI

publisher-version

Zeitschriftenartikel

Lv, G.; Tian, G.; Chen, G.; Zhu, S.; Bao, J.; Qin, C.; Zou, X.; Hu, J.; Seeberger, P. H.; Yin, J.: Chemical synthesis of the highly functionalized O-antigen repeating unit from Pseudomonas aeruginosa serotype O3 for glycoconjugate vaccine development. Chinese Chemical Letters 37 (2), 111875 (2026)

MPG.PuRe

DOI

Zeitschriftenartikel

Touloumdjian, C. S.; Reuber, E.; Weber, F.; Uncos, R. E.; Elhalem, E.; Bellomo, A.; Comin, M. J.; Marco, J. D.; Seeberger, P. H.; Donadío, L. G.: Enabling the serodiagnosis of American tegumentary leishmaniasis using synthetic aminopentyl-galactofuranoside-containing oligosaccharide epitopes. Organic & Biomolecular Chemistry 24 (2), S. 488 - 494 (2026)

MPG.PuRe

DOI

Zeitschriftenartikel

Mishra, A. K.; Reuber, E.; Rai, D.; Sander, L. E.; Duerr, J.; Graeber, S. Y.; Mall, M. A.; Fries, B. C.; Seeberger, P. H.; Kulkarni, S. S.: Chemical synthesis of Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii capsular polysaccharide fragments as leads for cross-protection. Angewandte Chemie International Edition, e24231 (2025)

MPG.PuRe

DOI

Zeitschriftenartikel

Pinzón-López, S.; Ebert, D.; Reuber, E.; Kraume, M.; Seeberger, P. H.; Danglad-Flores, J.: Bulk mixing in a milligram-scale solid phase batch reactor. Organic Process Research & Development (2025)

MPG.PuRe

DOI

Zeitschriftenartikel

Busuttil, K.; Pittman, N.; Zachary, J.; Halder, S.; Geilen, L.; Singh, A.; Misseldine, A.; Kaplonek, P.; Chipman, P.; Heimburg-Molinaro, J. et al.; Seeberger, P. H.; Mietzsch, M.; Bennett, A. D.; McKenna, R.: Mapping the sialic acid-binding sites of LuIII and H-1 parvovirus. Journal of Virology 99 (8), e00297-25 (2025)

MPG.PuRe

DOI

publisher-version

Zeitschriftenartikel

Chen, G.; Tian, G.; Hu, J.; Qin, C.; Zou, X.; Cai, J.; Lv, G.; Gao, W.; Seeberger, P. H.; Yin, J.: Chemical synthesis elucidates the absolute configuration and key antigenic epitope of Vibrio cholerae serotype O100 O-antigen. Science Advances 11 (17), eadv0571 (2025)

MPG.PuRe

DOI

publisher-version

Zeitschriftenartikel

Geue, N.; Greis, K.; Omoregbee-Leichnitz, S.; Kirschbaum, C.; Chang, C.-W.; Meijer, G.; von Helden, G.; Seeberger, P. H.; Pagel, K.: Influence of levulinoyl protecting groups on glycosylation stereoselectivity and glycosyl cation structure. European Journal of Organic Chemistry 28 (44), e202500732 (2025)

MPG.PuRe

DOI

publisher-version

10.

Zeitschriftenartikel

Ghosh, C.; Yao, L.; Sigler, M.; Di Lella, S.; Cagnoni, A.; Rabinovich, G.; Seeberger, P. H.: Design of galectin-1-conjugated nanoparticles as potential immunomodulatory agents. RSC Medicinal Chemistry 16 (12), S. 6041 - 6047 (2025)

MPG.PuRe

DOI

publisher-version

11.

Zeitschriftenartikel

Ledvinka, J.; Kullmann, R.; Reuber, E.; Weikl, T. R.; Garcia Ricardo, M.; Seeberger, P. H.: Stapling of β-glucans increases antibody binding. Journal of the American Chemical Society 147 (41), S. 37634 - 37640 (2025)

MPG.PuRe

DOI

publisher-version

12.

Zeitschriftenartikel

Li, L.; Hu, J.; Qin, C.; Cai, J.; Zou, X.; Tian, G.; Seeberger, P. H.; Yin, J.: Immunological evaluation of the autism-related bacterium Enterocloster bolteae capsular polysaccharide driven by chemical synthesis. Chinese Chemical Letters 36 (9), 110797 (2025)

MPG.PuRe

DOI

13.

Zeitschriftenartikel

Lühle, J.; Krost, S.; Goerdeler, F.; Valentí, A.; Shanin, E.; Seitz, C.; Seeberger, P. H.; Moscovitz, O.: Bifunctional cysteine-engineered CAR-T cells enable thiol-mediated targeting to overcome antigen escape in B cell lymphoma. ACS Central Science 11 (10), S. 1852 - 1861 (2025)

MPG.PuRe

DOI

publisher-version

14.

Zeitschriftenartikel

Michel, M.; Stijlemans, B.; Michel, D.; Garg, M.; Geißner, A.; Seeberger, P. H.; Varón Silva, D.: Detection of antibodies against the African parasite Trypanosoma brucei using synthetic glycosylphosphatidylinositol oligosaccharide fragments. Glycoconjugate Journal 42 (3-4), S. 147 - 158 (2025)

MPG.PuRe

DOI

publisher-version

15.

Zeitschriftenartikel

Omoregbee-Leichnitz, S.; Reuber, E.; Weber, F.; Stolte, K. N.; Danglad-Flores, J.; Dommisch, H.; Seeberger, P. H.: Automated glycan assembly of Porphyromonas gingivalis lipopolysaccharide epitopes for vaccine design. Journal of the American Chemical Society 147 (29), S. 25969 - 25977 (2025)

MPG.PuRe

DOI

publisher-version

16.

Zeitschriftenartikel

Pradhan, K.; Reuber, E.; Sletten, E. T.; Tomaso, H.; Seeberger, P. H.: A synthetic oligosaccharide resembling Francisella tularensis strain 15 O-antigen capsular polysaccharide as a lead for tularemia diagnostics and therapeutics. Angewandte Chemie International Edition 64 (4), e202416432 (2025)

MPG.PuRe

DOI

publisher-version

17.

Zeitschriftenartikel

Qin, C.; Han, W.; Tian, G.; Zou, X.; Maciejewska, A.; Lukasiewicz, J.; Seeberger, P. H.; Hu, J.; Yin, J.: Antigenicity evaluation of the synthetic trisaccharides related to Plesiomonas shigelloides serotype O51 O-antigen containing an acetamidino group. Carbohydrate Research 550, 109388 (2025)

MPG.PuRe

DOI

18.

Zeitschriftenartikel

Reuber, E.; Hickey, E.; Pradhan, A.; Sprute, R.; Lingscheid, T.; Tober-Lau, P.; Leaves, I.; Stappers, M. H. T.; Kurth, F.; Bruno, M. et al.; Netea, M. G.; Sander, L. E.; Cornely, O. A.; Gow, N. A. R.; Brown, A. J. P.; Singh, R. K.; Omoregbee-Leichnitz, S.; Sletten, E. T.; Danglad-Flores, J.; Seeberger, P. H.: Glycan microarray analysis of Candida-related antibodies in human and mice sera guides biomarker discovery and vaccine development. Proceedings of the National Academy of Sciences of the United States of America 122 (39), e2505340122 (2025)

MPG.PuRe

DOI

publisher-version

19.

Zeitschriftenartikel

Sianturi, J.; Weber, F.; Singh, R. K.; Lingscheid, T.; Tober-Lau, P.; Kurth, F.; Fries, B. C.; Seeberger, P. H.: Klebsiella pneumoniae Glycoconjugate Vaccine Leads Based on Semi-Synthetic O1 and O2ac Antigens. Angewandte Chemie International Edition 64 (7), e202419516 (2025)

MPG.PuRe

DOI

publisher-version

20.

Zeitschriftenartikel

Chang, C.-W.; Greis, K.; Prabhu, G. R. D.; Wehner, D.; Kirschbaum, C.; Ober, K.; Torres-Boy, A. Y.; Leichnitz, S.; Meijer, G.; von Helden, G. et al.; Seeberger, P. H.; Pagel, K.: Mechanistic insight into benzylidene-directed glycosylation reactions using cryogenic infrared spectroscopy. Nature Synthesis 3 (2024)

MPG.PuRe

DOI

publisher-version

21.

Zeitschriftenartikel

Danglad-Flores, J. A.; Sletten, E. T.; Reuber, E.; Bienert, K.; Riegler, H.; Seeberger, P. H.: Optimized platform for automated glycan assembly. Device 2 (10), 100499 (2024)

MPG.PuRe

DOI

publisher-version

22.

Zeitschriftenartikel

Jordan, C.; Siebold, K.; Priegue, P.; Seeberger, P. H.; Gilmour, R.: A fluorinated sialic acid vaccine lead against meningitis B and C. Journal of the American Chemical Society 146 (22), S. 15366 - 15375 (2024)

MPG.PuRe

DOI

publisher-version

23.

Zeitschriftenartikel

Shen, D.; Silva Seco, B. M.; Teixeira Alves, L. G.; Yao, L.; Bräutigam, M.; Opitz, B.; Witzenrath, M.; Fries, B. C.; Seeberger, P. H.: Semisynthetic glycoconjugate vaccine lead against klebsiella pneumoniae serotype O2afg induces functional antibodies and reduces the burden of acute pneumonia. Journal of the American Chemical Society 146 (51), S. 35356 - 35366 (2024)

MPG.PuRe

DOI

publisher-version

24.

Zeitschriftenartikel

Standvoss, K.; Kazezian, V.; Lewke, B. R.; Bastian, K.; Chidambaram, S.; Arafat, S.; Alsharif, U.; Herrera-Melendez, A.; Knipper, A.-D.; Silva Seco, B. M. et al.; Soto, N. N.; Rakitzis, O.; Steinecker, I.; van Kronenberg Till, P.; Zarebidaki, F.; Abbasi, P.; Weissgerber, T. L.: Shortcut citations in the methods section: frequency, problems, and strategies for responsible reuse. PLOS Biology 22 (4), e3002562 (2024)

MPG.PuRe

DOI

publisher-version

25.

Zeitschriftenartikel

Tian, G.; Hu, J.; Qin, C.; Li, L.; Ning, Y.; Zhu, S.; Xie, S.; Zou, X.; Seeberger, P. H.; Yin, J.: Chemical synthesis and antigenicity evaluation of an aminoglycoside trisaccharide repeating unit of Pseudomonas aeruginosa Serotype O5 O-Antigen containing a rare dimeric-ManpN3NA. Journal of the American Chemical Society 146 (27), S. 18427 - 18439 (2024)

MPG.PuRe

DOI

26.

Zeitschriftenartikel

Wrage, M.; Holland, T.; Nüse, B.; Kaltwasser, J.; Fröhlich, J.; Arnold, H.; Gießler, C.; Flamann, C.; Bruns, H.; Berges, J. et al.; Daniel, C.; Hoffmann, M. H.; Anish, C.; Seeberger, P. H.; Bogdan, C.; Dettmer, K.; Rauh, M.; Mattner, J.: Cell type-specific modulation of metabolic, immune-regulatory, and anti-microbial pathways by CD101. Mucosal immunology, S. 892 - 910 (2024)

MPG.PuRe

DOI

publisher-version

27.

Zeitschriftenartikel

Zhao, M.; Tian, G.; Qin, C.; Zou, X.; Seeberger, P. H.; Hu, J.; Yin, J.: Immunological exploration of Helicobacter pylori serotype O2 O-antigen by using a synthetic glycan library. Chinese Journal of Chemistry 42 (3), S. 243 - 251 (2024)

MPG.PuRe

DOI

28.

Zeitschriftenartikel

Baryzewska, A.; Roth, C.; Seeberger, P. H.; Zeininger, L.: In situ tracking of exoenzyme activity using droplet luminescence concentrators for ratiometric detection of bacteria. ACS Sensors 8 (11), S. 4143 - 4151 (2023)

MPG.PuRe

DOI

publisher-version

29.

Zeitschriftenartikel

Bialangi, N.; Mustapa, M. A.; Salimi, Y.; Musa, W.; Widiyantoro, A.; Ibrahim, A. M.; Situmeang, B.; Sianturi, J.: Evaluation of the antiplasmodial properties of Andrographis paniculata (Burm.f.) and Peperomia pellucida (L.) Kunth. Indonesian Journal of Chemistry 23 (1), S. 62 - 72 (2023)

MPG.PuRe

DOI

publisher-version

30.

Zeitschriftenartikel

Goerdeler, F.; Reuber, E.; Lühle, J.; Leichnitz, S.; Freitag, A.; Nedielkov, R.; Groza, R.; Ewers, H.; Möller, H. M.; Seeberger, P. H. et al.; Moscovitz, O.: Thiol-mediated uptake of a cysteine-containing nanobody for anticancer drug delivery. ACS Central Science 9 (6), S. 1111 - 1118 (2023)

MPG.PuRe

DOI

publisher-version

31.

Zeitschriftenartikel

Kastner, M.; Karner, A.; Zhu, R.; Huang, Q.; Geißner, A.; Sadewasser, A.; Lesch, M.; Wörmann, X.; Karlas, A.; Seeberger, P. H. et al.; Wolff, T.; Hinterdorfer, P.; Herrmann, A.; Sieben, C.: Relevance of host cell surface glycan structure for cell specificity of influenza A viruses. Viruses 15 (7), 1507 (2023)

MPG.PuRe

DOI

publisher-version

32.

Zeitschriftenartikel

Khilji, S. K.; Op 't Hoog, C.; Warschkau, D.; Lühle, J.; Goerdeler, F.; Freitag, A.; Seeberger, P. H.; Moscovitz, O.: Smaller size packs a stronger punch: recent advances in small antibody fragments targeting tumour-associated carbohydrate antigens. Theranostics 13 (9), S. 3041 - 3063 (2023)

MPG.PuRe

DOI

publisher-version

33.

Zeitschriftenartikel

Lewis, A. L.; Toukach, P.; Bolton, E.; Chen, X.; Frank, M.; Lütteke, T.; Knirel, Y.; Schoenhofen, I.; Varki, A.; Vinogradov, E. et al.; Woods, R. J.; Zachara, N.; Zhang, J.; Kamerling, J. P.; Neelamegham, S.; Seeberger, P. H.; the SNFG Discussion Group: Cataloging natural sialic acids and other nonulosonic acids (NulOs), and their representation using the Symbol Nomenclature for Glycans. Glycobiology 33 (2), S. 99 - 103 (2023)

MPG.PuRe

DOI

34.

Zeitschriftenartikel

Sabbavarapu, N. M.; Seeberger, P. H.: Automated glycan assembly of mycobacterial hexaarabinofuranoside and docosasaccharide arabinan (Araf₂₃) motifs found on mycobacterium tuberculosis. Chemistry – A European Journal 29 (23), e202300032 (2023)

MPG.PuRe

DOI

publisher-version

35.

Zeitschriftenartikel

Sabbavarapu, N. M.; Seeberger, P. H.: Automated glycan assembly of highly branched heptadecasaccharide repeating unit of arabinogalactan polysaccharide HH1-1 from Carthamus tinctorius. Chemical Communications 59 (32), S. 4822 - 4824 (2023)

MPG.PuRe

DOI

publisher-version

36.

Zeitschriftenartikel

Singh, R. K.; Reuber, E.; Bruno, M.; Netea, M. G.; Seeberger, P. H.: Synthesis of oligosaccharides to identify an immunologically active epitope against Candida auris infection. Chemical Science 14 (27), S. 7559 - 7563 (2023)

MPG.PuRe

DOI

publisher-version

37.

Zeitschriftenartikel

Ben Ami Pilo, H.; Khilji, S. K.; Lühle, J.; Biskup, K.; Levy Gal, B.; Rosenhek Goldian, I.; Alfandari, D.; Revach, O.-Y.; Kiper, E.; Morandi, M. I. et al.; Rotkopf, R.; Porat, Z.; Blanchard, V.; Seeberger, P. H.; Regev-Rudzki, N.; Moscovitz, O.: Sialylated N-glycans mediate monocyte uptake of extracellular vesicles secreted from Plasmodium falciparum-infected red blood cells. Journal of Extracellular Biology 1 (2), e33 (2022)

MPG.PuRe

DOI

publisher-version

38.

Zeitschriftenartikel

Boyraz, B.; Saatz, J.; Pompös, I.-M.; Gad, M.; Dernedde, J.; Maier, A.-K. B.; Moscovitz, O.; Seeberger, P. H.; Traub, H.; Tauber, R.: Imaging keratan sulfate in ocular tissue sections by immunofluorescence microscopy and LA-ICP-MS. ACS applied bio materials 5 (2), S. 853 - 861 (2022)

MPG.PuRe

DOI

39.

Zeitschriftenartikel

Garcia Ricardo, M.; Reuber, E.; Yao, L.; Danglad-Flores, J. Á.; Delbianco, M.; Seeberger, P. H.: Design, synthesis, and characterization of stapled oligosaccharides. Journal of the American Chemical Society 144 (40), S. 18429 - 18434 (2022)

MPG.PuRe

DOI

publisher-version

40.

Zeitschriftenartikel

Ghosh, C.; Priegue, P.; Leelayuwapan,, H.; Fuchsberger, F. F.; Rademacher, C.; Seeberger, P. H.: Synthetic glyconanoparticles modulate innate immunity but not the complement system. ACS applied bio materials 5 (5), S. 2185 - 2192 (2022)

MPG.PuRe

DOI

publisher-version

Martin, C. E., Broecker, F., Eller, S., Oberli, M. A., Anish, C., Pereira, C. L., Seeberger, P. H.

Glycan arrays containing synthetic Clostridium difficile lipoteichoic acid oligomers as tools toward a carbohydrate vaccine

Chem.Commun. 2013, Accepted Manuscript �

Martin, C. E., Broecker, F., Oberli, M. A., Komor, J., Mattner, J., Anish, C., Seeberger, P. H

Immunological Evaluation of a Synthetic Clostridium difficile Oligosaccharide Conjugate Vaccine Candidate and Identification of a Minimal Epitope

J. Am. Chem. Soc. 2013 Articles ASAP (As Soon As Publishable)

Yang, Y.; Oishi, S.; Martin, C. E.; Seeberger, P. H

Diversity-oriented Synthesis of Inner Core Oligosaccharides of the Lipopolysaccharide of Pathogenic Gram-negative Bacteria

J. Am. Chem. Soc. 2013, 135, 6262–6271.

Source

Yang, Y., C. E. Martin, Seeberger, P. H.

Total synthesis of the core tetrasaccharide of Neisseria meningitidis lipopolysaccharide, a potential vaccine candidate for meningococcal diseases

Chem. Sci. 2012, 3, 896-899.

Source

Martin, C. E., M. W. Weishaupt, Seeberger, P. H.

Progress toward developing a carbohydrate-conjugate vaccine against Clostridium difficile ribotype 027: synthesis of the cell-surface polysaccharide PS-I repeating unit

Chem. Commun. 2011, 47, 10260-10262.

Source