Max-Planck-Institut für Kolloid- und Grenzflächenforschung

Publications

Zeitschriftenartikel (226)

1.

Zeitschriftenartikel

Reuber, E.; Pradhan, A.; Leaves, I.; Singh, R. K.; Hickey, E.; Geiler, C.; Gow, N. A. R.; Brown, A. J. P.; Seeberger, P. H.: A synthetic β‐mannan epitope enables immunization and detection of Candida auris. Angewandte Chemie International Edition, e9466991 (2026)

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2.

Zeitschriftenartikel

Weber, F.; Valentí, A.; Ledvinka, J.; Moscovitz, O.; Seeberger, P. H.: Using synthetic glycans to investigate anti‐glycan antibodies and explore their medical potential. Angewandte Chemie International Edition, e7795967 (2026)

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3.

Zeitschriftenartikel

La Pietra, L.; Pillich, H.; Hudel, M.; Berisha, B.; Abu Mraheil, M.; Geißner, A.; Seeberger, P. H.; Chakraborty, T.: Heparin-binding enhances extracellular listeriolysin O activity, overcoming cholesterol inhibition and pH dependence. Journal of Bacteriology (2026)

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4.

Zeitschriftenartikel

Freitag, A.; Khilji, S. K.; Nedielkov, R.; Murali Kumar, S.; Krummhaar, M.; Arndt, J.; Moreira, G. M. S. G.; Lühle, J.; Goerdeler, F.; Kamphues, C. et al.; Mroginski, M. A.; Roth, C.; Seeberger, P. H.; Möller, H. M.; Moscovitz, O.: Integrative approach to develop and characterize antibodies against the cancer-associated antigen sialyl Lewis A (CA 19-9). JACS Au 6 (4), S. 2274 - 2287 (2026)

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5.

Zeitschriftenartikel

Geue, N.; Greis, K.; Omoregbee-Leichnitz, S.; Kirschbaum, C.; Meijer, G.; von Helden, G.; Seeberger, P. H.; Marianski, M.; Pagel, K.: Evaluating participation modes in peracetylated glycosyl cations. Organic Letters 28 (14), S. 4337 - 4342 (2026)

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6.

Zeitschriftenartikel

Han, W.; Qin, C.; Tong, W.; Yang, K.; Tian, X.; Zhang, J.-R.; Liu, J.; Seeberger, P. H.; Hu, J.; Yin, J.: Preclinical development of a well-defined semisynthetic glycoconjugate vaccine against Haemophilus influenzae type b. Science Advances 12 (9), eaea8116 (2026)

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7.

Zeitschriftenartikel

Kortman, H.; Fang, H.; Bastick, K. A. C.; Völkel, C.; Oberthür, D.; Seeberger, P. H.; Perbandt, M.; Molloy, J. J.: Fused 3D boron heterocycles via EnT catalysis: synthesis, modification and validation as beta-lactamase inhibitors. Chemical Science 17 (1), S. 247 - 254 (2026)

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8.

Zeitschriftenartikel

Krull, J.; Sidhu, C.; Solanki, V.; Bligh, M.; Rößler, L.; Singh, R. K.; Huang, G.; Robb, C. S.; Teeling, H.; Seeberger, P. H. et al.; Schweder, T.; Crawford, C.; Hehemann, J.-H.: Sulfated mannan of diatoms selects host-specific microbiota in the sunlit ocean. Microbiome 14, 112 (2026)

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9.

Zeitschriftenartikel

Lühle, J.; Seeberger, P. H.; Moscovitz, O.: Cell surface thiol-disulfide regulation in cancer: mechanisms, implications, and theranostic strategies. Redox Biology: an official journal of the Society for Free Radical Biology and Medicine 92, 104142 (2026)

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10.

Zeitschriftenartikel

Lv, G.; Tian, G.; Chen, G.; Zhu, S.; Bao, J.; Qin, C.; Zou, X.; Hu, J.; Seeberger, P. H.; Yin, J.: Chemical synthesis of the highly functionalized O-antigen repeating unit from Pseudomonas aeruginosa serotype O3 for glycoconjugate vaccine development. Chinese Chemical Letters 37 (2), 111875 (2026)

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11.

Zeitschriftenartikel

Mishra, A. K.; Reuber, E.; Rai, D.; Sander, L. E.; Duerr, J.; Graeber, S. Y.; Mall, M. A.; Fries, B. C.; Seeberger, P. H.; Kulkarni, S. S.: Chemical synthesis of Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii capsular polysaccharide fragments as leads for cross-protection. Angewandte Chemie International Edition 65 (6), e24231 (2026)

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12.

Zeitschriftenartikel

Sigler, M.; Hon, C.; Pohl, K. G.; Sander, L. E.; Garcia Ricardo, M.; Seeberger, P. H.: Solid-phase glycolipid synthesis expedites liposome functionalization. Journal of the American Chemical Society 148 (28), S. 30486 - 30493 (2026)

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13.

Zeitschriftenartikel

Touloumdjian, C. S.; Reuber, E.; Weber, F.; Uncos, R. E.; Elhalem, E.; Bellomo, A.; Comin, M. J.; Marco, J. D.; Seeberger, P. H.; Donadío, L. G.: Enabling the serodiagnosis of American tegumentary leishmaniasis using synthetic aminopentyl-galactofuranoside-containing oligosaccharide epitopes. Organic & Biomolecular Chemistry 24 (2), S. 488 - 494 (2026)

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14.

Zeitschriftenartikel

Wang, Y.; Lu, W.; Lin, X.; Yuan, Z.; You, Z.; Peng, Y.; Zhu, S.; Wang, H.; Dong, Z.; Lu, F.: A signature peptide strategy for concurrent detection of multiple pathogens and toxins in infant formula. Journal of Agricultural and Food Chemistry 74 (14), S. 11785 - 11796 (2026)

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15.

Zeitschriftenartikel

Zhang, S.; Daněk, O.; Seeberger, P. H.: Total synthesis of the capsular polysaccharide repeating unit towards the development of a glycoconjugate vaccine against Klebsiella pneumoniae ST512. Beilstein Journal of Organic Chemistry 22 (1), S. 821 - 827 (2026)

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16.

Zeitschriftenartikel

Zou, X.; Qin, C.; Fu, J.; Tian, G.; Hu, J.; Seeberger, P. H.; Yu, B.; Yin, J.: Carbohydrate-based vaccine engineering (CVE): an integrated strategy against bacterial infections. Glycoscience & Therapy 2 (2), 100039 (2026)

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17.

Zeitschriftenartikel

Busuttil, K.; Pittman, N.; Zachary, J.; Halder, S.; Geilen, L.; Singh, A.; Misseldine, A.; Kaplonek, P.; Chipman, P.; Heimburg-Molinaro, J. et al.; Seeberger, P. H.; Mietzsch, M.; Bennett, A. D.; McKenna, R.: Mapping the sialic acid-binding sites of LuIII and H-1 parvovirus. Journal of Virology 99 (8), e00297-25 (2025)

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18.

Zeitschriftenartikel

Chen, G.; Tian, G.; Hu, J.; Qin, C.; Zou, X.; Cai, J.; Lv, G.; Gao, W.; Seeberger, P. H.; Yin, J.: Chemical synthesis elucidates the absolute configuration and key antigenic epitope of Vibrio cholerae serotype O100 O-antigen. Science Advances 11 (17), eadv0571 (2025)

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19.

Zeitschriftenartikel

Geue, N.; Greis, K.; Omoregbee-Leichnitz, S.; Kirschbaum, C.; Chang, C.-W.; Meijer, G.; von Helden, G.; Seeberger, P. H.; Pagel, K.: Influence of levulinoyl protecting groups on glycosylation stereoselectivity and glycosyl cation structure. European Journal of Organic Chemistry 28 (44), e202500732 (2025)

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20.

Zeitschriftenartikel

Ghosh, C.; Yao, L.; Sigler, M.; Di Lella, S.; Cagnoni, A.; Rabinovich, G.; Seeberger, P. H.: Design of galectin-1-conjugated nanoparticles as potential immunomodulatory agents. RSC Medicinal Chemistry 16 (12), S. 6041 - 6047 (2025)

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21.

Zeitschriftenartikel

Ledvinka, J.; Kullmann, R.; Reuber, E.; Weikl, T. R.; Garcia Ricardo, M.; Seeberger, P. H.: Stapling of β-glucans increases antibody binding. Journal of the American Chemical Society 147 (41), S. 37634 - 37640 (2025)

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22.

Zeitschriftenartikel

Li, L.; Hu, J.; Qin, C.; Cai, J.; Zou, X.; Tian, G.; Seeberger, P. H.; Yin, J.: Immunological evaluation of the autism-related bacterium Enterocloster bolteae capsular polysaccharide driven by chemical synthesis. Chinese Chemical Letters 36 (9), 110797 (2025)

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23.

Zeitschriftenartikel

Lühle, J.; Krost, S.; Goerdeler, F.; Valentí, A.; Shanin, E.; Seitz, C.; Seeberger, P. H.; Moscovitz, O.: Bifunctional cysteine-engineered CAR-T cells enable thiol-mediated targeting to overcome antigen escape in B cell lymphoma. ACS Central Science 11 (10), S. 1852 - 1861 (2025)

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24.

Zeitschriftenartikel

Michel, M.; Stijlemans, B.; Michel, D.; Garg, M.; Geißner, A.; Seeberger, P. H.; Varón Silva, D.: Detection of antibodies against the African parasite Trypanosoma brucei using synthetic glycosylphosphatidylinositol oligosaccharide fragments. Glycoconjugate Journal 42 (3-4), S. 147 - 158 (2025)

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25.

Zeitschriftenartikel

Omoregbee-Leichnitz, S.; Reuber, E.; Weber, F.; Stolte, K. N.; Danglad-Flores, J.; Dommisch, H.; Seeberger, P. H.: Automated glycan assembly of Porphyromonas gingivalis lipopolysaccharide epitopes for vaccine design. Journal of the American Chemical Society 147 (29), S. 25969 - 25977 (2025)

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26.

Zeitschriftenartikel

Pinzón-López, S.; Ebert, D.; Reuber, E.; Kraume, M.; Seeberger, P. H.; Danglad-Flores, J.: Bulk mixing in a milligram-scale solid phase batch reactor. Organic Process Research & Development 29 (9), S. 2275 - 2286 (2025)

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27.

Zeitschriftenartikel

Pradhan, K.; Reuber, E.; Sletten, E. T.; Tomaso, H.; Seeberger, P. H.: A synthetic oligosaccharide resembling Francisella tularensis strain 15 O-antigen capsular polysaccharide as a lead for tularemia diagnostics and therapeutics. Angewandte Chemie International Edition 64 (4), e202416432 (2025)

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28.

Zeitschriftenartikel

Qin, C.; Han, W.; Tian, G.; Zou, X.; Maciejewska, A.; Lukasiewicz, J.; Seeberger, P. H.; Hu, J.; Yin, J.: Antigenicity evaluation of the synthetic trisaccharides related to Plesiomonas shigelloides serotype O51 O-antigen containing an acetamidino group. Carbohydrate Research 550, 109388 (2025)

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29.

Zeitschriftenartikel

Reuber, E.; Hickey, E.; Pradhan, A.; Sprute, R.; Lingscheid, T.; Tober-Lau, P.; Leaves, I.; Stappers, M. H. T.; Kurth, F.; Bruno, M. et al.; Netea, M. G.; Sander, L. E.; Cornely, O. A.; Gow, N. A. R.; Brown, A. J. P.; Singh, R. K.; Omoregbee-Leichnitz, S.; Sletten, E. T.; Danglad-Flores, J.; Seeberger, P. H.: Glycan microarray analysis of Candida-related antibodies in human and mice sera guides biomarker discovery and vaccine development. Proceedings of the National Academy of Sciences of the United States of America 122 (39), e2505340122 (2025)

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30.

Zeitschriftenartikel

Sianturi, J.; Weber, F.; Singh, R. K.; Lingscheid, T.; Tober-Lau, P.; Kurth, F.; Fries, B. C.; Seeberger, P. H.: Klebsiella pneumoniae Glycoconjugate Vaccine Leads Based on Semi-Synthetic O1 and O2ac Antigens. Angewandte Chemie International Edition 64 (7), e202419516 (2025)

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31.

Zeitschriftenartikel

Chang, C.-W.; Greis, K.; Prabhu, G. R. D.; Wehner, D.; Kirschbaum, C.; Ober, K.; Torres-Boy, A. Y.; Leichnitz, S.; Meijer, G.; von Helden, G. et al.; Seeberger, P. H.; Pagel, K.: Mechanistic insight into benzylidene-directed glycosylation reactions using cryogenic infrared spectroscopy. Nature Synthesis 3 (2024)

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32.

Zeitschriftenartikel

Danglad-Flores, J. A.; Sletten, E. T.; Reuber, E.; Bienert, K.; Riegler, H.; Seeberger, P. H.: Optimized platform for automated glycan assembly. Device 2 (10), 100499 (2024)

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33.

Zeitschriftenartikel

Jordan, C.; Siebold, K.; Priegue, P.; Seeberger, P. H.; Gilmour, R.: A fluorinated sialic acid vaccine lead against meningitis B and C. Journal of the American Chemical Society 146 (22), S. 15366 - 15375 (2024)

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34.

Zeitschriftenartikel

Shen, D.; Silva Seco, B. M.; Teixeira Alves, L. G.; Yao, L.; Bräutigam, M.; Opitz, B.; Witzenrath, M.; Fries, B. C.; Seeberger, P. H.: Semisynthetic glycoconjugate vaccine lead against klebsiella pneumoniae serotype O2afg induces functional antibodies and reduces the burden of acute pneumonia. Journal of the American Chemical Society 146 (51), S. 35356 - 35366 (2024)

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35.

Zeitschriftenartikel

Standvoss, K.; Kazezian, V.; Lewke, B. R.; Bastian, K.; Chidambaram, S.; Arafat, S.; Alsharif, U.; Herrera-Melendez, A.; Knipper, A.-D.; Silva Seco, B. M. et al.; Soto, N. N.; Rakitzis, O.; Steinecker, I.; van Kronenberg Till, P.; Zarebidaki, F.; Abbasi, P.; Weissgerber, T. L.: Shortcut citations in the methods section: frequency, problems, and strategies for responsible reuse. PLOS Biology 22 (4), e3002562 (2024)

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36.

Zeitschriftenartikel

Tian, G.; Hu, J.; Qin, C.; Li, L.; Ning, Y.; Zhu, S.; Xie, S.; Zou, X.; Seeberger, P. H.; Yin, J.: Chemical synthesis and antigenicity evaluation of an aminoglycoside trisaccharide repeating unit of Pseudomonas aeruginosa Serotype O5 O-Antigen containing a rare dimeric-ManpN3NA. Journal of the American Chemical Society 146 (27), S. 18427 - 18439 (2024)

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37.

Zeitschriftenartikel

Wrage, M.; Holland, T.; Nüse, B.; Kaltwasser, J.; Fröhlich, J.; Arnold, H.; Gießler, C.; Flamann, C.; Bruns, H.; Berges, J. et al.; Daniel, C.; Hoffmann, M. H.; Anish, C.; Seeberger, P. H.; Bogdan, C.; Dettmer, K.; Rauh, M.; Mattner, J.: Cell type-specific modulation of metabolic, immune-regulatory, and anti-microbial pathways by CD101. Mucosal immunology, S. 892 - 910 (2024)

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38.

Zeitschriftenartikel

Zhao, M.; Tian, G.; Qin, C.; Zou, X.; Seeberger, P. H.; Hu, J.; Yin, J.: Immunological exploration of Helicobacter pylori serotype O2 O-antigen by using a synthetic glycan library. Chinese Journal of Chemistry 42 (3), S. 243 - 251 (2024)

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39.

Zeitschriftenartikel

Baryzewska, A.; Roth, C.; Seeberger, P. H.; Zeininger, L.: In situ tracking of exoenzyme activity using droplet luminescence concentrators for ratiometric detection of bacteria. ACS Sensors 8 (11), S. 4143 - 4151 (2023)

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40.

Zeitschriftenartikel

Bialangi, N.; Mustapa, M. A.; Salimi, Y.; Musa, W.; Widiyantoro, A.; Ibrahim, A. M.; Situmeang, B.; Sianturi, J.: Evaluation of the antiplasmodial properties of Andrographis paniculata (Burm.f.) and Peperomia pellucida (L.) Kunth. Indonesian Journal of Chemistry 23 (1), S. 62 - 72 (2023)

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Martin, C. E., Broecker, F., Eller, S., Oberli, M. A., Anish, C., Pereira, C. L., Seeberger, P. H.

Glycan arrays containing synthetic Clostridium difficile lipoteichoic acid oligomers as tools toward a carbohydrate vaccine

Chem.Commun. 2013, Accepted Manuscript �

original

original

Martin, C. E., Broecker, F., Oberli, M. A., Komor, J., Mattner, J., Anish, C., Seeberger, P. H

Immunological Evaluation of a Synthetic Clostridium difficile Oligosaccharide Conjugate Vaccine Candidate and Identification of a Minimal Epitope

J. Am. Chem. Soc. 2013 Articles ASAP (As Soon As Publishable)

original

original

Yang, Y.; Oishi, S.; Martin, C. E.; Seeberger, P. H

Diversity-oriented Synthesis of Inner Core Oligosaccharides of the Lipopolysaccharide of Pathogenic Gram-negative Bacteria

J. Am. Chem. Soc. 2013, 135, 6262–6271.

original

original

Yang, Y., C. E. Martin, Seeberger, P. H.

Total synthesis of the core tetrasaccharide of Neisseria meningitidis lipopolysaccharide, a potential vaccine candidate for meningococcal diseases

Chem. Sci. 2012, 3, 896-899.

original

original

Martin, C. E., M. W. Weishaupt, Seeberger, P. H.

Progress toward developing a carbohydrate-conjugate vaccine against Clostridium difficile ribotype 027: synthesis of the cell-surface polysaccharide PS-I repeating unit

Chem. Commun. 2011, 47, 10260-10262.

original

original