Buchkapitel (71)
2017
Buchkapitel
The role of metal ions in the mussel byssus. In: Physiology of molluscs: a collection of selected reviews, two volumes set, Ch. 4, Volume 1 Aufl., S. 113 - 152 (Hg. Saleuddin, S.; Mukai, S.). Apple Academic Press, New Jersey (2017)
Buchkapitel
Profile analysis tensiometry for studies of liquid interfacial dynamics. In: Laser optofluidics in fighting multiple drug resistance, S. 41 - 74 (Hg. Pascu, M. L.). Bentham Science Publishers, Dubai, U.A.E. (2017)
2016
Buchkapitel
5, S. 431 - 452 (Hg. Miller, R.; Liggieri, L.). CRC; Taylor & Francis, Boca Raton, FL (2016)
Numerical Solution, Stability, and Control of Acoustic Cavitation-Bubble Dynamics. In: Progress in Colloid and Interface Science, Bd.
Buchkapitel
Faivre, D.). Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim (2016)
Magnetoreception and Magnetotaxis. In: Iron Oxides: From Nature to Applications, S. 567 - 590 (Hg.
Buchkapitel
5, S. 3 - 40 (Hg. Miller, R.; Liggieri, L.). CRC; Taylor & Francis, Boca Raton, FL (2016)
Thermodynamics of Adsorption at Liquid Interfaces. In: Progress in Colloid and Interface Science, Bd.
Buchkapitel
Bioinspirierte Gestaltung von Materialien. In: +ultra gestaltung schafft wissen, S. 177 - 182 (Hg. Doll, N.; Bredekamp, H.; Schäffner, W.). Seemann & Henschel, Leipzig (2016)
Buchkapitel
Foams. In: Ullmann's Encyclopedia of Industrial Chemistry, S. 1 - 31. Wiley-VCH, Weinheim, Germany (2016)
Buchkapitel
An introduction into the physics of self-folding thin structures. In: On Folding. Towards a New Field of Interdisciplinary Research, S. 175 - 210 (Hg. Friedman, M.; Schäffner, W.). transcript Verlag, Bielefeld (2016)
Buchkapitel
5, S. 83 - 104 (Hg. Miller, R.; Liggieri, L.). CRC; Taylor & Francis, Boca Raton, FL (2016)
Dynamics of Interfacial Layer Formation. In: Progress in Colloid and Interface Science, Bd.
Buchkapitel
5, S. 467 - 480 (Hg. Miller, R.; Liggeri , L.). CRC; Taylor & Francis, Boca Raton, FL (2016)
Solutal Marangoni Convection: Challenges in Fluid Dynamics with Mass Transfer. In: Progress in Colloid and Interface Science, Bd.
Buchkapitel
5, S. 183 - 195 (Hg. Miller, R.; Liggieri, L.). CRC; Taylor & Francis, Boca Raton, FL (2016)
Macroscale Computational Techniques in Interfacial Science. In: Progress in Colloid and Interface Science, Bd.
Buchkapitel
5, S. 59 - 82 (Hg. Miller, R.; Liggieri, L.). CRC; Taylor & Francis, Boca Raton, FL (2016)
Experimental Approaches and Related Theories. In: Progress in Colloid and Interface Science, Bd.
Buchkapitel
5, S. 413 - 430 (Hg. Miller, R.; Liggeri , L.). CRC; Taylor & Francis, Boca Raton, FL (2016)
Approximate Analytical Solution via ADM and Numerical Simulation of Acoustic Cavitation: Bubble Dynamics. In: Progress in Colloid and Interface Science, Bd.
Buchkapitel
Influence of Condensed Phosphates on the Physical Chemistry of Calcium Phosphate Solids. In: Inorganic Polyphosphates in Eukaryotic Cells, S. 177 - 205 (Hg. Kulakovskaya, T.; Pavlov, E.; Dedkova, E. N.). Springer International Publishing, Switzerland (2016)
Buchkapitel
5, S. 149 - 167 (Hg. Miller, R.; Liggieri, L.). CRC; Taylor & Francis, Boca Raton, FL (2016)
Mesoscale Computational Techniques in Interfacial Science: Lattice Boltzmann Method. In: Progress in Colloid and Interface Science, Bd.
Buchkapitel
5, S. 169 - 181 (Hg. Miller, R.; Liggieri, L.). CRC; Taylor & Francis, Boca Raton, FL (2016)
Mesoscale Computational Techniques in Interfacial Science: Smoothed Particle Hydrodynamics Method. In: Progress in Colloid and Interface Science, Bd.
Buchkapitel
Faivre, D.). Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim (2016)
Mineralization of Goethite in Limpet Radular Teeth. In: Iron Oxides: From Nature to Applications, S. 207 - 224 (Hg.
Buchkapitel
Faivre, D.). Wiley-VCH, Weinheim (2016)
Actuation of Iron Oxide-Based Nanostructures by External Magnetic Fields. In: Iron Oxides: From Nature to Applications, S. 523 - 544 (Hg. 2015
Buchkapitel
Magnetotactic bacteria. In: Microswimmers - From single particle motion to collective behaviour, S. B5.1 - B5.13 (Hg. Gompper, G.; Bechinger, C.). Forschungszentrum Jülich, Jülich (2015)
Buchkapitel
Thermodynamic Models for the Adsorption of Alkyl Trimethyl Ammonium Bromides at the Water/Hexane Interface. In: Colloid Process Engineering, S. 309 - 321 (Hg. Kind, M.; Peukert, W.; Rehage, H.; Schuchmann, H. P.). Springer International Publishing, Cham (2015)
Buchkapitel
Hydro-Actuated Plant Devices. In: Nonlinear Elasticity and Hysteresis: Fluid-Solid Coupling in Porous Media, S. 171 - 200 (Hg. Kim, A. H.; Guyer, R. A.). Wiley-VCH, Weinheim (2015)
Buchkapitel
Structural and Mechanical Characterization of Growing Arabidopsis Plant Cell Walls. In: Plant Cell Expansion: Methods and Protocols, S. 211 - 227 (Hg. Estevez, J. M.). Springer, New York (2015)
Buchkapitel
Simulation techniques for solvation-induced surface-interactions at prescribed water chemical potential. In: Computational Trends in Solvation and Transport in Liquids - Lecture Notes (IAS Series 28), S. 155 - 185 (Hg. Sutman, G.; Grotendorst, J.; Gompper, G.; Marx, D.). Forschungszentrum Jülich, Jülich (2015)
2014
Buchkapitel
Wetting instabilities in Langmuir-Blodgett film deposition. In: Surfactant Science and Technology: Retrospects and Prospects, S. 193 - 212 (Hg. Romstedt, L.). CRC Press/Taylor and Francis Group, Boca Raton (2014)
Buchkapitel
Surfactant Adsorption Layers at Liquid Interfaces. In: Surfactant Science and Technology: Retrospects and Prospects, S. 149 - 170 (Hg. Romstedt, L.). CRC Press/Taylor and Francis Group, Boca Raton (2014)
Buchkapitel
Einfluß von Proteinen auf die Schaumbildung und Schaumstabilität. In: Proteinschäume in der Lebensmittelproduktion: Mechanismenaufklärung, Modellierung und Simulation, S. 11 - 30 (Hg. Häusser, V.; Kinkel, D.). Bonner Universitäts-Buchdruckerei, Bonn (2014)
Buchkapitel
14, S. 33 - 46 (Hg. Balke, F.; Siegert, B.; Vogl, J.). Wilhelm Fink, Paderborn (2014)
Modelle in der Computersimulation: aktuelle Herausforderungen. In: Modelle und Modellierung, Bd. 2013
Buchkapitel
Magnetosomes. In: Bionanotechnology: Biological Self-Assembly and its Applications, S. 241 - 271 (Hg. Rehm, B. H. A.). Caister Academic Press, Wymondham (2013)
Buchkapitel
Magnetic nanoparticles in bacteria. In: Materials Design Inspired by Nature: Function Through Inner Architecture, S. 235 - 255 (Hg.
Buchkapitel
Understanding hierarchy and functions of bone using scanning X-ray scattering methods. In: Materials Design Inspired by Nature: Function Through Inner Architecture, S. 46 - 73 (Hg.
Buchkapitel
Bone structural adaptation and Wolff’s law. In: Materials Design Inspired by Nature: Function Through Inner Architecture, S. 17 - 45 (Hg.
Buchkapitel
Magnetite minerals in the human brain: What is their role? In: Medical Geochemistry: Geological Materials and Health, S. 91 - 99 (Hg. Censi, P.). Springer, Dordrecht (2013)
2012
Buchkapitel
Hierarchy in natural materials. In: Hierarchically Structured Porous Materials, S. 29 - 39 (Hg. Su, B.-L.; Sanchez, C.). Wiley-VCH, Weinheim (2012)
Buchkapitel
Magnetic Nanoparticles in Magnetosomes. In: Nature's Nanostructures, S. 249 - 271 (Hg. Barnard, A. S.; Guo, H.). Pan Stanford Publ., Singapore (2012)
Buchkapitel
9, S. 35 - 55 (Hg. Matyjaszewski, K.; Möller, M.). Elsevier, Amsterdam (2012)
Collagen. In: Polymer science: a comprehensive reference, Bd. 2011
Buchkapitel
52, S. 3 - 27. Springer, Berlin, Heidelberg (2011)
Magnetite biomineralization in bacteria. In: Progress in molecular and subcellular biology, Bd.
Buchkapitel
9, S. 27 - 52. Springer, Berlin (2011)
Micromechanis of cell walls. In: Signaling and Communication in Plants, Bd.
Buchkapitel
The skeleton: Cartilaginous fish skeletal anatomy. In: Encyclopedia of fish physiology: from genome to environment, S. 419 - 427 (Hg. Farrell, A. P.). Academic Press, San Diego (2011)
Buchkapitel
The skeleton: Cartilaginous fish skeletal tissues. In: Encyclopedia of fish physiology: from genome to environment, S. 428 - 433 (Hg. Farrell, A. P.). Academic Press, San Diego (2011)
Buchkapitel
3, S. 407 - 426 (Hg. Ducheyne, P.; Healy, k. E.; Hutmacher, D. W.; Grainger, D. W.; Kirkpatrick, C. J.). Elsevier, Amsterdam (2011)
Imaging mineralized tissues in vertebrates. In: Comprehensive biomaterials, Bd. 2010
Buchkapitel
Combined (in situ) methods. In: Industrial applications of natural fibres: structure, properties and technical applications, S. 337 - 343 (Hg. Müssig, J.). Wiley, Chichester (2010)
Buchkapitel
Natural fibres - function in nature. In: Industrial applications of natural fibres: structure, properties and technical applications, S. 23 - 39 (Hg. Müssig, J.). Wiley, Chichester (2010)
Buchkapitel
Role of amelogenin self-assembly in protein-mediated dental enamel formation. In: Interface oral health science 2009, S. 369 - 374 (Hg. Sasano, T.; Suzuki, O.). Springer, Tokyo (2010)
2009
Buchkapitel
Bone nanostructure and its relevance for mechanical performance, disease and treatment. In: Nanotechnology Volume 5: Nanomedicine, S. 345 - 360 (Hg. Vogel, V.). Wiley-VCH, Weinheim (2009)
Buchkapitel
Raman application in bone imaging. In: Raman spectroscopy for soft matter applications, S. 227 - 267 (Hg. Amer, M. S.). Wiley, Hoboken (2009)
2008
Buchkapitel
Fratzl, P.). Springer, New York (2008)
Collagen: structure and mechanics, an introduction. In: Collagen: structure and mechanics, S. 1 - 13 (Hg.
Buchkapitel
Mechanical design of biomineralized tissues. Bone and other hierarchical materials. In: Metal ions in life sciences Vol. 4, Biomineralization: from nature to application, S. 547 - 575 (Hg. Sigel, A.; Sigel, H.; Sigel, R. K. O.). Wiley, Chichester (2008)
Buchkapitel
Fratzl, P.). Springer, New York (2008)
Nanoscale deformation mechanisms in collagen. In: Collagen: structure and mechanics, S. 155 - 173 (Hg.
Buchkapitel
Fratzl, P.). Springer, New York (2008)
Dentin. In: Collagen: structure and mechanics, S. 421 - 446 (Hg. 2007
Buchkapitel
Nanoscale mechanisms of bone deformation and fracture. In: Handbook of biomineralization: biological aspects and structure formation, S. 397 - 414 (Hg. Bäuerlein, E.). Wiley-VCH, Weinheim (2007)
Buchkapitel
Hierarchical structure and repair of bone deformation, remodelling, healing. In: Self healing materials: an alternative approach to 20 centuries of materials science, S. 323 - 335 (Hg. van der Zwaag, S.). Springer, Berlin (2007)
2006
Buchkapitel
Mechanics of the expanding cell wall. In: The expanding cell, S. 191 - 215 (Hg. Verbelen, J. P.; Vissenberg, K.). Springer, Berlin (2006)
Buchkapitel
Mechanics of the wood cell wall. In: Characterization of the cellulosic cell wall, S. 30 - 37 (Hg. Stokke, D. D.; Groom, L. H.). Blackwell, Oxford (2006)
Buchkapitel
Material properties: mineral crystals. In: The bone quality book - a guide to factors influencing bone strength, S. 56 - 63 (Hg. Dempster, D.; Felsenberg, D.; van der Geest, S.). Elsevier, Amsterdam (2006)
Buchkapitel
Complex biological structures: collagen and bone. In: Neutron scattering in biology: techniques and applications, S. 205 - 223 (Hg. Fitter, J.; Katsaras, J.). Springer, Berlin (2006)
2004
Buchkapitel
Phase separation in binary alloys - modeling approaches. In: Moving interfaces in crystalline solids, S. 57 - 116 (Hg. Fischer, F. D.). Springer, Vienna (2004)
Buchkapitel
Influence of mineral particle characteristics on the local mechanical properties of human crown dentin. In: Biomineralization (BIOM 2001): formation, diversity, evolution and application, S. 353 - 356 (Hg. Kobayashi, I.; Ozawa, H.). Tokai University Press, Kanagawa (2004)
Konferenzbeitrag (20)
2019
Konferenzbeitrag
28 (1), S. 50 - 50 (2019)
Loss of mechanosensitivity in a mouse model for gerodermia osteodysplastica due to an altered lacuno-canalicular osteocyte network. Osteologie 2019, Frankfurt am Main, 28. März 2019 - 30. März 2019. Osteologie
Konferenzbeitrag
11113, 1111318, (2019)
A load frame for in situ tomography at PETRA III. Proceedings of SPIE 2015
Konferenzbeitrag
Three-dimensional investigation of the relationship between orientation and microelastic properties of mineralized collagen fibrils in human osteonal bone. In: 6th European Symposium on Ultrasonic Characterization of Bone (ESUCB 2015), S. 1 - 4. 6th European Symposium on Ultrasonic Characterization of Bone (ESUCB 2015), Corfu, Greece, 10. Juni 2015 - 12. Juni 2015. IEEE (2015)
Konferenzbeitrag
21 (Supplement S3), S. 2007 - 2008 (2015)
Elemental and Phase Analysis of the Stomatopod Dactyl Club by X-Ray Mapping. The Official M&M 2015 Proceedings, Portland, Oregon, USA, 02. August 2015 - 06. August 2015. Microscopy and Microanalysis 2012
Konferenzbeitrag
From cell contractility to curvature-controlled tissue growth. In: 10th International Symposium on Biomechanics and Biomedical Engineering, 124. 10th International Symposium on Biomechanics and Biomedical Engineering, Berlin, 11. April 2012. (2012)
2010
Konferenzbeitrag
247, 012031, (2010)
Mineral crystal alignment in mineralized fracture callus determined by 3D small-angle X-ray scattering. Journal of Physics: Conference Series 2009
Konferenzbeitrag
1188, 1188-LL09-04, (2009)
Architectured structural materials: a parallel between nature and engineering. MRS Symposium Proceedings
Konferenzbeitrag
1187, KK01-05, (2009)
Mechanical function of a complex three-dimensional suture joining the bony elements in the shell of the red-eared slider turtle. MRS Symposium Proceedings 2007
Konferenzbeitrag
40, S. S78 - S82 (2007)
Scanning X-ray imaging with small-angle scattering contrast. Journal of Applied Crystallography
Konferenzbeitrag
40, S. S564 - S567 (2007)
Fracture of poly(vinylidene fluoride): a combined synchrotron and laboratory in-situ X-ray scattering study. Journal of Applied Crystallography
Konferenzbeitrag
40, S. S466 - S470 (2007)
A new experimental station for simultaneous X-ray microbeam scanning for small- and wide-angle scattering and fluorescence at BESSY II. Journal of Applied Crystallography
Konferenzbeitrag
40, S. S522 - S526 (2007)
Pore lattice deformation in ordered mesoporous silica studied by in situ small-angle X-ray diffraction. Journal of Applied Crystallography 2006
Konferenzbeitrag
132, S. 117 - 123 (2006)
Mechanical Properties of Freestanding Polyelectrolyte Capsules: a Quantitative Approach Based on Shell Theory. Progress in Colloid and Polymer Science 2005
Konferenzbeitrag
The stick-slip mechanism in wood: evidence for a critical role of hemicelluloses in the mechanical performance. In: The Hemicelluloses Workshop 2005, S. 69 - 75 (Hg. Entwistle, K. M.; Walker, J. C. F.). The Hemicelluloses Workshop, University of Canterbury, Christchurch, New Zealand, 10. Januar 2005 - 12. Januar 2005. Wood Technology Research Centre, Christchurch (2005)
Konferenzbeitrag
874, L5.11, S. 79 - 84 (2005)
Relating local bone stiffness and calcium content by combined nanoindentation and backscattered electron imaging. MRS Symposium Proceedings
Konferenzbeitrag
874, L1.9, S. 67 - 72 (2005)
Architectural changes of trabecular bone caused by the remodeling process. MRS Symposium Proceedings
Konferenzbeitrag
874, L7.9, (2005)
The influence of the thermal treatment of hydroxylapatite scaffolds on the physical properties and the bone cell ingrowth behaviour. MRS Symposium Proceedings 2004
Konferenzbeitrag
Hierarchical structure and mechanical adaptation of biological materials. In: Learning from Nature How to Design New Implantable Biomaterialsis: From Biomineralization Fundamentals to Biomimetic Materials and Processing Routes, S. 15 - 34 (Hg. Reis, R. L.; Weiner, S.). NATO Advanced Study Institute, Alvor, Algarve, 13. Oktober 2003 - 24. Oktober 2003. Springer, Dordrecht (2004)
Konferenzbeitrag
782, A5.17, (2004)
3D small angle X-ray scattering (SAXS) on deformed PVDF foils. MRS Symposium Proceedings
Konferenzbeitrag
823, W8.8, (2004)
Regular, low density cellular structures - rapid prototyping, numerical simulation, mechanical testing. MRS Symposium Proceedings Meeting Abstract (36)
2019
Meeting Abstract
28 (1), S. 45 - 45. Thieme, Stuttgart (2019)
Somatic activating mutations in MAP2K1 cause melorheostosis with highly porous lesions covered by compact periosteal bone. In Ostelologie,
Meeting Abstract
104 (Suppl. 1), P122, S. S98. ECTS Congress 2019 : 46th European Calcified Tissue Society Congress, Budapest, 11. Mai 2019 - 14. Mai 2019. Springer-Verlag, New York (2019)
Correlations between the osteocyte network and its surrounding matrix in newly formed bone. In Calcified Tissue International,
Meeting Abstract
104 (Suppl. 1), P125, S. S48. ECTS 2019, Budapest, Hungary, 11. Mai 2019 - 14. Mai 2019. Springer-Verlag, New York (2019)
Relationship between the fluid flow pattern through the lacunocanalicular network and adaptive mechano-response in mouse tibia. In Calcified Tissue International, 2018
Meeting Abstract
Communicating Coral Skeletal Data through Microscopic Images (#PA41E-1364). In AGU Fall Meetin Online Scientific Program https://fallmeeting.agu.org/2018/program-overview/. Amercian Geophysical Union, Fall Meeting 2018, Washington, D.C., 10. Dezember 2018 - 14. Dezember 2018. (2018)
2017
Meeting Abstract
57 (suppl_1). Society of Integrative and Comparative Biology, McLean, VA (2017)
Bricks and anchors: strategies for load bearing and muscle attachment in the cartilage skeletons of sharks and rays. In Integrative and Comparative Biology,
Meeting Abstract
112 (3) Supplement 1 Aufl., S. 567a. Cell Press, Cambridge, Mass. (2017)
Magneto-Aerotaxis: Bacterial Motility in Magnetic Fields. In Biophysical Journal,
Meeting Abstract
46 (Suppl. 1), P-221, S. S172 - S172. 19th IUPAB Congress / 11th EBSA Congress Location: British Biophys Soc, Edinburgh, Scotland, 16. Juli 2017 - 20. Juli 2017. Springer, Berlin (2017)
Understanding the interplay between amino acid sequence and water in collagen mimetic peptides. In European Biophysics Journal with Biophysics Letters, 2016
Meeting Abstract
Exploiting interactions between bisphosphonate and bioactive glass as a strategy to develop novel hybrid materials for bone regeneration. In Frontiers in Bioengineering and Biotechnology, 1988. 10th World Biomaterials Congress, Montréal, Canada , 17. Mai 2016 - 22. Mai 2016. (2016)
Meeting Abstract
Effect of very small addition of non-ionic surfactants on the adsorption of proteins from low concentrated solutions – what we call “mosquito effect”. In Smart and Green Interfaces Conference-SGIC2015: Joint with COST meeting Annual MC–Program and Book of Abstracts, S. 9. Smart and Green Interfaces Conference - SGIC2015, Belgrad, Serbien, 30. März 2015 - 01. April 2015. (2016)
2015
Meeting Abstract
29 (1) Suppl Aufl., 702.9. The Federation, Bethesda, Md. (2015)
Cartilage or Bone? Collagens in “Cartilaginous” Fish Skeletons Answer an Old Question. In The FASEB Journal,
Meeting Abstract
21, S. S103 - S103. 4th TERMIS World Congress, Boston, MA, 08. September 2015 - 11. September 2015. Mary Ann Liebert, Larchmont, NY (2015)
3D Tissue Growth in vivo under Geometrical Constraints. In Tissue Engineering Part A, 2014
Meeting Abstract
248. 248th National Meeting of the American-Chemical-Society (ACS), San Francisco, CA, 10. August 2014 - 14. August 2014. (2014)
Yellow fluorescent protein senses and reports mechanical damage in fiber-reinforced polymer composites. In Abstracts of Papers of the American Chemical Society,
Meeting Abstract
8 (Supplement s1), K39 (S 24/25), S. 6 - 38. John Wiley & Sons, Ltd. (2014)
Enhancing soft matter mechanics via metal coordination: lessons from the mussel byssus. In Journal of Tissue Engineering and Regenerative Medicine,
Meeting Abstract
54 (suppl_1), E191. Society of Integrative and Comparative Biology, McLean, VA (2014)
Morphology and distribution of interlacunar canals in elasmobranch mineralized cartilage. In Integrative and Comparative Biology, 2013
Meeting Abstract
296 (ICVM Abstract) Special Feature Aufl., C-103, S. 220. Wiley-Liss, Hoboken (2013)
Feeding biomechanics in billfish: Inferring the role of the rostrum during feeding in two billfish species. In The Anatomical Record,
Meeting Abstract
245. (2013)
Soft microorigami: Shape-programmed folding of stimuli-responsive polymer films. In Abstracts of Papers of the American Chemical Society,
Meeting Abstract
245, 201-PMSE. (2013)
Influence of macromolecule-grafting on the interfacial adhesion in composites. In Abstracts of Papers of the American Chemical Society,
Meeting Abstract
296 (ICVM Abstract) Special Feature Aufl., P-022, S. 257. Wiley-Liss, Hoboken (2013)
Morphology and distribution of interlacunar canals in elasmobranch mineralized cartilage. In The Anatomical Record, 2012
Meeting Abstract
45 (Supplement 1), S61. Elsevier, New York (2012)
The effect of structure and morphology on the light transmissivity of the mineralized spines of lanternsharks. In Journal of Biomechanics,
Meeting Abstract
50 (Suppl. 1), S. S125 - S126. Elsevier, New York (2012)
Functional mapping of bone on the micrometer-scale by scanning acoustic microscopy. In Bone,
Meeting Abstract
50 (Suppl. 1), S. S129 - S129. Elsevier, New York (2012)
Mineral particle size in children with dominant osteogenesis imperfecta is not associated with specific collagen mutation: A synchrotron X-ray scattering study. In Bone,
Meeting Abstract
50 (Suppl. 1), PP111, S. S99 - S100. Elsevier, New York (2012)
Evidence of polyphosphates and their distribution in active biological apatite mineralization sites of stingray jaws. In Bone,