Publications of Christoph Rademacher

Ghosh, C.; Priegue, P.; Leelayuwapan,, H.; Fuchsberger, F. F.; Rademacher, C.; Seeberger, P. H.: Synthetic glyconanoparticles modulate innate immunity but not the complement system. ACS applied bio materials 5 (5), pp. 2185 - 2192 (2022)

Shanina, E.; Kuhaudomlarp, S.; Lal, K.; Seeberger, P. H.; Imberty, A.; Rademacher, C.: Druggable allosteric sites in β-propeller lectins. Angewandte Chemie International Edition 61 (1), e202109339 (2022)

Shanina, E.; Kuhaudomlarp, S.; Siebs, E.; Fuchsberger, F. F.; Denis, M.; da Silva Figueiredo Celestino Gomes, P.; Clausen, M. H.; Seeberger, P. H.; Rognan, D.; Titz, A. et al.; Imberty, A.; Rademacher, C.: Targeting undruggable carbohydrate recognition sites through focused fragment library design. Communications Chemistry 5, 64 (2022)

Siebs, E.; Shanina, E.; Kuhaudomlarp, S.; da Silva Figueiredo Celestino Gomes, P.; Fortin, C.; Seeberger, P. H.; Rognan, D.; Rademacher, C.; Imberty, A.; Titz, A.: Targeting the central pocket of the Pseudomonas aeruginosa lectin LecA. Chembiochem 23 (3), e202100563 (2022)

Zhang, H.-X.; Daněk, O.; Makarov, D.; Rádl, S.; Kim, D.; Ledvinka, J.; Vychodilová, K.; Hlaváč, J.; Lefèbre, J.; Denis, M. et al.; Rademacher, C.; Ménová, P.: Drug-like inhibitors of DC-SIGN based on a quinolone scaffold. ACS Medicinal Chemistry Letters 13 (6), pp. 935 - 942 (2022)

Bellmann, L.; Zelle-Rieser, C.; Milne, P.; Resteu, A.; Tripp, C. H.; Hermann-Kleiter, N.; Zaderer, V.; Wilflingseder, D.; Hörtnagl, P.; Theochari, M. et al.; Schulze, J.; Rentzsch, M.; Del Frari, B.; Collin, M.; Rademacher, C.; Romani, N.; Stoitzner, P.: Notch-mediated generation of monocyte-derived Langerhans cells: phenotype and function. Journal of Investigative Dermatology 141 (1), pp. 84 - 94.e6 (2021)

Fittolani, G.; Shanina, E.; Guberman, M.; Seeberger, P. H.; Rademacher, C.; Delbianco, M.: Automated glycan assembly of ¹⁹F labelled glycan probes enables high‐throughput NMR studies of protein‐glycan interactions. Angewandte Chemie International Edition 60 (24), pp. 13302 - 13309 (2021)

Hendriks, A.; van Dalen, R.; Ali, S.; Gerlach, D.; van der Marel, G. A.; Fuchsberger, F. F.; Aerts, P. C.; de Haas, C. J.C.; Peschel, A.; Rademacher, C. et al.; van Strijp, J. A.G.; Codée, J. D.C.; van Sorge, N. M.: Impact of glycan linkage to staphylococcus aureus wall teichoic acid on langerin recognition and Langerhans cell activation. ACS Infectious Diseases 7 (3), pp. 624 - 635 (2021)

Joswig, J.-O.; Anders, J.; Zhang, H.-X.; Rademacher, C.; Keller, B. G.: The molecular basis for the pH-dependent calcium affinity of the pattern recognition receptor langerin. The Journal of Biological Chemistry 296, 100718 (2021)

Kuhaudomlarp, S.; Siebs, E.; Shanina, E.; Topin, J.; Joachim, I.; da Silva Figueiredo Celestino Gomes, P.; Varrot, A.; Rognan, D.; Rademacher, C.; Imberty, A. et al.; Titz, A.: Non-carbohydrate glycomimetics as inhibitors of calcium(II)-binding lectins. Angewandte Chemie International Edition 60 (15), pp. 8104 - 8114 (2021)

Rentzsch, M.; Wawrzinek, R.; Zelle-Rieser, C.; Strandt, H.; Bellmann, L.; Fuchsberger, F. F.; Schulze, J.; Busmann, J.; Rademacher, J.; Sigl, S. et al.; Del Frari, B.; Stoitzner, P.; Rademacher, C.: Specific protein antigen delivery to human Langerhans cells in intact skin. Frontiers in immunology 12, 732298 (2021)

Shanina, E.; Siebs, E.; Zhang, H.-X.; Varón Silva, D.; Joachim, I.; Titz, A.; Rademacher, C.: Protein-observed 19F NMR of LecA from Pseudomonas aeruginosa. Glycobiology 31 (2), pp. 159 - 165 (2021)

Wawrzinek, R.; Wamhoff, E.-C.; Lefebre, J.; Rentzsch, M.; Bachem, G.; Domeniconi, G.; Schulze, J.; Fuchsberger, F. F.; Zhang, H.-X.; Modenutti, C. et al.; Schnirch, L.; Marti, M. A.; Schwardt, O.; Bräutigam, M.; Guberman, M.; Hauck, D.; Seeberger, P. H.; Seitz, O.; Titz, A.; Ernst, B.; Rademacher, C.: A remote secondary binding pocket promotes heteromultivalent targeting of DC-SIGN. Journal of the American Chemical Society 143 (45), pp. 18977 - 18988 (2021)

Bachem, G.; Wamhoff, E.-C.; Silberreis, K.; Kim, D.; Baukmann, H.; Fuchsberger, F. F.; Dernedde, J.; Rademacher, C.; Seitz, O.: Rational design of an DNA-scaffolded high-affinity binder for langerin. Angewandte Chemie International Edition 59 (47), pp. 21016 - 21022 (2020)

Keller, B. G.; Rademacher, C.: Allostery in C-type lectins. Current Opinion in Structural Biology 62, pp. 31 - 38 (2020)

Mende, M.; Tsouka, A.; Heidepriem, J.; Paris, G.; Mattes, D. S.; Eickelmann, S.; Bordoni, V.; Wawrzinek, R.; Fuchsberger, F. F.; Seeberger, P. H. et al.; Rademacher, C.; Delbianco, M.; Mallagaray, A.; Löffler, F. F.: On-chip neo-glycopeptide synthesis for multivalent glycan presentation. Chemistry – A European Journal 26 (44), pp. 9954 - 9963 (2020)

Mostinski, Y.; Heynen, G. J. J. E.; López-Alberca, M. P.; Paul, J.; Miksche, S.; Radetzki, S.; Schaller, D.; Shanina, E.; Seyffarth, C.; Kolomeets, Y. et al.; Ziebart, N.; de Schryver, J.; Oestreich, S.; Neuenschwander, M.; Roske, Y.; Heinemann, U.; Rademacher, C.; Volkamer, A.; von Kries, J. P.; Birchmeier, W.; Nazaré, M.: From pyrazolones to azaindoles: evolution of active-site SHP2 inhibitors based on scaffold hopping and bioisosteric replacement. Journal of Medicinal Chemistry 63 (23), pp. 14780 - 14804 (2020)

Troelsen, N.; Shanina, E.; Gonzalez-Romero, D.; Danková, D.; Jensen, I.; Sniady, K.; Nami, F.; Zhang, H.-X.; Rademacher, C.; Cuenda, A. et al.; Gotfredsen, C.; Clausen, M. H.: The 3F library: fluorinated Fsp3-rich fragments for expeditious 19F-NMR-based screening. Angewandte Chemie, International Edition 59 (6), pp. 2204 - 2210 (2020)

van Dalen, R.; Fuchsberger, F. F.; Rademacher, C.; van Strijp, J. A. G.; van Sorge, N. M.: A common genetic variation in Langerin (CD207) compromises cellular uptake of Staphylococcus aureus. Journal of Innate Immunity 12 (2), pp. 191 - 200 (2020)

Aretz, J.; Rademacher, C.: Ranking Hits From Saturation Transfer Difference Nuclear Magnetic Resonance–Based Fragment Screening. Frontiers in Chemistry 7, 215 (2019)