Publikationen von Christoph Rademacher

Hanske, J.; Wawrzinek, R.; Geissner, A.; Wamhoff, E.-C.; Sellrie, K.; Schmidt, H.; Seeberger, P. H.; Rademacher, C.: Calcium-independent activation of an allosteric network in Langerin by heparin oligosaccharides. ChemBioChem: A European Journal of Chemical Biology 18 (13), S. 1183 - 1187 (2017)

Mallagaray, A.; Rademacher, C.; Parra, F.; Hansman, G.; Peters, T.: Saturation transfer difference nuclear magnetic resonance titrations reveal complex multistep-binding of l-fucose to norovirus particles. Glycobiology 27 (1), S. 80 - 86 (2017)

Spiliotopoulos, D.; Wamhoff, E.-C.; Lolli, G.; Rademacher, C.; Caflisch, A.: Discovery of BAZ2A bromodomain ligands. European Journal of Medicinal Chemistry 139 (Supplement C), S. 564 - 572 (2017)

Spiliotopoulos, D.; Zhu, J.; Wamhoff, E.-C.; Deerain, N.; Marchand, J.-R.; Aretz, J.; Rademacher, C.; Caflisch, A.: Virtual screen to NMR (VS2NMR): discovery of fragment hits for the CBP bromodomain. Bioorganic & Medicinal Chemistry Letters 27 (11), S. 2472 - 2478 (2017)

Aretz, J.; Kondoh, Y.; Honda, K.; Anumala, U. R.; Nazaré, M.; Watanabe, N.; Osada, H.; Rademacher, C.: Chemical fragment arrays for rapid druggability assessment. Chemical Communications 52 (58), S. 9067 - 9070 (2016)

Aretz, J.; Wratil, P. R.; Wamhoff, E.-C.; Nguyen, H. G.; Reutter, W.; Rademacher, C.: Fragment-screening of N-acetylmannosamine kinase reveals non-carbohydrate inhibitors. Canadian Journal of Chemistry 94 (11), S. 920 - 926 (2016)

Broecker, F.; Hanske, J.; Martin, C. E.; Baek, J. Y.; Wahlbrink, A.; Wojcik, F.; Hartmann, L.; Rademacher, C.; Chakkumkal, A.; Seeberger, P. H.: Multivalent display of minimal Clostridium difficile glycan epitopes mimics antigenic properties of larger glycans. Nature Communications 7, 11224 (2016)

Hanske, J.; Aleksić, S.; Ballaschk, M.; Jurk, M.; Shanina, E.; Beerbaum, M.; Schmieder, P.; Keller, B. G.; Rademacher, C.: Intradomain allosteric network modulates calcium affinity of the C-Type lectin receptor langerin. Journal of the American Chemical Society 138 (37), S. 12176 - 12186 (2016)

Wamhoff, E.-C.; Hanske, J.; Schnirch, L.; Aretz, J.; Grube, M.; Varón Silva, D.; Rademacher, C.: ¹⁹F NMR-guided design of glycomimetic Langerin ligands. ACS Chemical Biology 11 (9), S. 2407 - 2413 (2016)

Aretz, J.; Rademacher, C.: Fragmentbasierte Wirkstoffentwicklung. Nachrichten aus der Chemie 63 (2), S. 116 - 121 (2015)

Lee, C.; Hahne, D. G.; Hanske, J.; Bange, D. T.; Bier, D.; Rademacher, C.; Hennig, D. S.; Grossmann, D. T. N.: Redox Modulation of PTEN Phosphatase Activity by Hydrogen Peroxide and Bisperoxidovanadium Complexes. Angewandte Chemie International Edition 54, S. 13796 - 13800 (2015)

Aretz, J.; Wamhoff, E.-C.; Hanske, J.; Heymann, D.; Rademacher, C.: Computational and experimental prediction of human C-type lectin receptor druggability. Frontiers in immunology, 5:323 (2014)

Bröcker, F.; Aretz, J.; Yang, Y.; Hanske, J.; Guo, X.; Reinhardt, A.; Wahlbrink, A.; Rademacher, C.; Anish, C.; Seeberger, P. H.: Epitope recognition of antibodies against a Yersinia pestis lipopolysaccharide trisaccharide component. ACS Chemical Biology 9 (4), S. 867 - 873 (2014)

Glas, A.; Bier, D.; Hahne, G.; Rademacher, C.; Ottmann, C.; Grossmann, T.: Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction. Angewandte Chemie International Edition 53 (9), S. 2489 - 2493 (2014)

Ponader, D.; Maffre, P.; Aretz, J.; Pussak, D.; Ninnemann, N. M.; Schmidt, S.; Seeberger, P. H.; Rademacher, C.; Nienhaus, G. U.; Hartmann, L.: Carbohydrate-lectin recognition of sequence-defined heteromultivalent glycooligomers. Journal of the American Chemical Society 136 (5), S. 2008 - 2016 (2014)

Kawasaki, N.; Vela, J. L.; Nycholat, C. M.; Rademacher, C.; Khurana, A.; van Rooijen, N.; Crocker, P. R.; Kronenberg, M.; Paulson, J. C.: Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation. Proceedings of the National Academy of Sciences of the United States of America 110 (19), S. 7826 - 7831 (2013)

Macauley, M. S.; Pfrengle, F.; Rademacher, C.; Nycholat, C. M.; Gale, A. J.; von Drygalski, A.; Paulson, J. C.: Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis. The Journal of Clinical Investigation 123 (7), S. 3074 - 3083 (2013)

Rillahan, C. D.; Schwartz, E.; Rademacher, C.; McBride, R.; Rangarajan, J.; Fokin, V. V.; Paulson, J. C.: On-chip synthesis and screening of a sialoside library yields a high affinity ligand for Siglec-7. ACS Chemical Biology 8 (7), S. 1417 - 1422 (2013)

Fiege, B.; Rademacher, C.; Cartmell, J.; Kitov, P. I.; Parra, F.; Peters, T.: Molecular Details of the Recognition of Blood Group Antigens by a Human Norovirus as Determined by STD NMR Spectroscopy. Angewandte Chemie International Edition 51 (4), S. 928 - 932 (2012)

Landström, J.; Persson, K.; Rademacher, C.; Lundborg, M.; Wakarchuk, W.; Peters, T.; Widmalm, G.: Small molecules containing hetero-bicyclic ring systems compete with UDP-Glc for binding to WaaG glycosyltransferase. Glycoconjugate Journal 29 (7), S. 491 - 502 (2012)