Publikationen von Eike-Christian Wamhoff

Wawrzinek, R.; Wamhoff, E.-C.; Lefebre, J.; Rentzsch, M.; Bachem, G.; Domeniconi, G.; Schulze, J.; Fuchsberger, F. F.; Zhang, H.-X.; Modenutti, C. et al.; Schnirch, L.; Marti, M. A.; Schwardt, O.; Bräutigam, M.; Guberman, M.; Hauck, D.; Seeberger, P. H.; Seitz, O.; Titz, A.; Ernst, B.; Rademacher, C.: A remote secondary binding pocket promotes heteromultivalent targeting of DC-SIGN. Journal of the American Chemical Society 143 (45), S. 18977 - 18988 (2021)

Bachem, G.; Wamhoff, E.-C.; Silberreis, K.; Kim, D.; Baukmann, H.; Fuchsberger, F. F.; Dernedde, J.; Rademacher, C.; Seitz, O.: Rational design of an DNA-scaffolded high-affinity binder for langerin. Angewandte Chemie International Edition 59 (47), S. 21016 - 21022 (2020)

Neuhaus, K.; Wamhoff, E.-C.; Freichel, T.; Grafmüller, A.; Rademacher, C.; Hartmann, L.: Asymmetrically branched precision glycooligomers targeting langerin. Biomacromolecules 20 (11), S. 4088 - 4095 (2019)

Wamhoff, E.-C.; Schulze, J.; Bellmann, L.; Rentzsch, M.; Bachem, G.; Fuchsberger, F. F.; Rademacher, J.; Hermann, M.; Del Frari, B.; van Dalen, R. et al.; Hartmann, D.; van Sorge, N.; Seitz, O.; Stoitzner, P.; Rademacher, C.: A specific, glycomimetic Langerin ligand for human Langerhans cell targeting. ACS Central Science 5 (5), S. 808 - 820 (2019)

Sommer, R.; Wagner, S.; Rox, K.; Varrot, A.; Hauck, D.; Wamhoff, E.-C.; Schreiber, J.; Ryckmans, T.; Brunner, T.; Rademacher, C. et al.; Hartmann, R. W.; Brönstrup, M.; Imberty, A.; Titz, A.: Glycomimetic, orally bioavailable LecB inhibitors block biofilm formation of Pseudomonas aeruginosa. Journal of the American Chemical Society 140 (7), S. 2537 - 2545 (2018)

Glas, A.; Wamhoff, E.-C.; Krüger, D. M.; Rademacher, C.; Grossmann, T. N.: Increased conformational flexibility of a macrocycle‒receptor complex contributes to reduced dissociation rates. Chemistry – A European Journal 23 (64), S. 16157 - 16161 (2017)

Hanske, J.; Wawrzinek, R.; Geissner, A.; Wamhoff, E.-C.; Sellrie, K.; Schmidt, H.; Seeberger, P. H.; Rademacher, C.: Calcium-independent activation of an allosteric network in Langerin by heparin oligosaccharides. ChemBioChem: A European Journal of Chemical Biology 18 (13), S. 1183 - 1187 (2017)

Spiliotopoulos, D.; Wamhoff, E.-C.; Lolli, G.; Rademacher, C.; Caflisch, A.: Discovery of BAZ2A bromodomain ligands. European Journal of Medicinal Chemistry 139 (Supplement C), S. 564 - 572 (2017)

Spiliotopoulos, D.; Zhu, J.; Wamhoff, E.-C.; Deerain, N.; Marchand, J.-R.; Aretz, J.; Rademacher, C.; Caflisch, A.: Virtual screen to NMR (VS2NMR): discovery of fragment hits for the CBP bromodomain. Bioorganic & Medicinal Chemistry Letters 27 (11), S. 2472 - 2478 (2017)

Aretz, J.; Wratil, P. R.; Wamhoff, E.-C.; Nguyen, H. G.; Reutter, W.; Rademacher, C.: Fragment-screening of N-acetylmannosamine kinase reveals non-carbohydrate inhibitors. Canadian Journal of Chemistry 94 (11), S. 920 - 926 (2016)

Möginger, U.; Resemann, A.; Martin, C. E.; Parameswarappa, S.; Govindan, S.; Wamhoff, E.-C.; Broecker, F.; Suckau, D.; Pereira, C. L.; Chakkumkal, A. et al.; Seeberger, P. H.; Kolarich, D.: Cross Reactive Material 197 glycoconjugate vaccines contain privileged conjugation sites. Scientific Reports 6, 20488 (2016)

Wamhoff, E.-C.; Hanske, J.; Schnirch, L.; Aretz, J.; Grube, M.; Varón Silva, D.; Rademacher, C.: ¹⁹F NMR-guided design of glycomimetic Langerin ligands. ACS Chemical Biology 11 (9), S. 2407 - 2413 (2016)

Frei, P.; Navarra, G.; Sager, C. P.; Silbermann, M.; Varga, N.; Wamhoff, E.-C.: Drug discovery summit: 11th Swiss course on medicinal chemistry. ChemMedChem 10 (3), S. 575 - 579 (2015)

Aretz, J.; Wamhoff, E.-C.; Hanske, J.; Heymann, D.; Rademacher, C.: Computational and experimental prediction of human C-type lectin receptor druggability. Frontiers in immunology, 5:323 (2014)

Nycholat, C. M.; Duan, S.; Willis, S.; Wamhoff, E.-C.; Arthur, C.; McBride, R.; Rademacher, C.; Stowell, S.; Paulson, J. C.: Synthetic glycan analog libraries for the development of selective, high affinity ligands of siglecs and galectins. In Glycobiology, 28 (12), 185, S. 1075 - 1076. Annual Meeting of the Society for Glycobiology, New Orleans, LA, 05. November 2018 - 08. November 2018. Oxford University Press, Oxford (2018)

Schulze, J.; Wamhoff, E.-C.; Rademacher, C.: Towards small molecule-based targeted delivery to immune cells. In FEBS Journal, 282 Supplement 1 Aufl., P15-027, S. 245 - 245. 40th Congress of the Federation-of-European-Biochemical-Societies (FEBS) - The Biochemical Basis of Life, Berlin, Germany, 04. Juli 2015 - 09. Juli 2015. Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies, Oxford, UK (2015)

Aretz, J.; Wamhoff, E.-C.; Hanske, J.; Heymann, D.; Rademacher, C.: Druggability of mammalian C-type lectin receptors. In Abstracts of Papers of the American Chemical Society, 248. 248th National Meeting of the American-Chemical-Society (ACS), San Francisco, CA, 10. August 2014 - 14. August 2014. (2014)

Wamhoff, E.-C.: Glycomimetic langerin ligands for Langerhans cell targeting. Dissertation, 320 S., Freie Universität Berlin, Berlin (2017)