Publications
Journal Article (51)
2014
Journal Article
21 (1), pp. 38 - 50 (2014)
Chemical biology approaches to designing defined carbohydrate vaccines. Chemistry & Biology
Journal Article
Computational and experimental prediction of human C-type lectin receptor druggability. Frontiers in immunology, 5:323 (2014)
Journal Article
15 (7), pp. 986 - 994 (2014)
A new bifunctional chelator enables facile biocoupling and radiolabeling as the basis for a bioconjugation kit. ChemBioChem: A European Journal of Chemical Biology
Journal Article
215 (1), pp. 90 - 95 (2014)
Ammonium carbamate functionalization of microgels for pH-sensitive loading and release of anionic and cationic molecules. Macromolecular Chemistry and Physics
Journal Article
9 (4), pp. 867 - 873 (2014)
Epitope recognition of antibodies against a Yersinia pestis lipopolysaccharide trisaccharide component. ACS Chemical Biology
Journal Article
1844 (1), pp. 108 - 116 (2014)
Validation of the curation pipeline of UniCarb-DB: building a global glycan reference MS/MS repository. Biochimica et Biophysica Acta-Proteins and Proteomics
Journal Article
10 (11), pp. 950 - 956 (2014)
A semisynthetic carbohydrate-lipid vaccine that protects against S-pneumoniae in mice. Nature Chemical Biology
Journal Article
58, pp. 1 - 8 (2014)
Electrochemical displacement sensor based on ferrocene boronic acid tracer and immobilized glycan for saccharide binding proteins and E. coli. Biosensors and Bioelectronics
Journal Article
15 (6), pp. 844 - 851 (2014)
Biological evaluation of multivalent Lewis X-MGL-1 interactions. ChemBioChem
Journal Article
14 (4), pp. 2130 - 2134 (2014)
Imaging early endothelial inflammation following stroke by core shell silica superparamagnetic glyconanoparticles that target selectin. Nano Letters
Journal Article
4, 6445 (2014)
Differential regulation of non-protein coding RNAs from Prader-Willi syndrome locus. Scientific Reports
Journal Article
18, pp. 38 - 45 (2014)
Glycan arrays as tools for infectious disease research. Current Opinion in Chemical Biology
Journal Article
50 (84), pp. 12652 - 12655 (2014)
Continuous synthesis of artemisinin-derived medicines. Chemical Communications
Journal Article
14 (3), pp. 410 - 418 (2014)
Continuous flow photochemistry. The Chemical Record
Journal Article
18 (12), pp. 1771 - 1776 (2014)
Continuous reductions and reductive aminations using solid NaBH4. Organic Process Research & Development
Journal Article
53 (9), pp. 2489 - 2493 (2014)
Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction. Angewandte Chemie International Edition
Journal Article
10 (35), pp. 6732 - 6741 (2014)
A novel contact model for AFM indentation experiments on soft spherical cell-like particles. Soft Matter
Journal Article
53 (50), pp. 13701 - 13705 (2014)
Diagnosis of toxoplasmosis using a synthetic glycosylphosphatidylinositol glycan. Angewandte Chemie International Edition
Journal Article
42 (10), pp. 6630 - 6644 (2014)
Identification and characterization of RNA guanine-quadruplex binding proteins. Nucleic Acids Research (London)
Journal Article
16 (6), pp. 1794 - 1797 (2014)
Continuous photochemical cleavage of linkers for solid-phase synthesis. Organic Letters
Journal Article
50 (15), pp. 1851 - 1853 (2014)
Automated glycopeptide assembly by combined solid-phase peptide and oligosaccharide synthesis. Chemical Communications
Journal Article
9 (7), e103281 (2014)
Role of the C-type lectin receptors MCL and DCIR in experimental colitis. PLoS One
Journal Article
50 (15), pp. 1875 - 1877 (2014)
Modular automated solid phase synthesis of dermatan sulfate oligosaccharides. Chemical Communications
Journal Article
12 (1), 59 (2014)
Carbohydrate functionalization of silver nanoparticles modulates cytotoxicity and cellular uptake. Journal of Nanobiotechnology
Journal Article
80 (19), pp. 5911 - 5917 (2014)
Carbohydrate-coating reduces adhesion of biofilm-forming Bacillus subtilis to gold surfaces. Applied and Environmental Microbiology
Journal Article
14 (3), pp. 428 - 439 (2014)
Kinetics and efficiency of a methyl-carboxylated 5-fluorouracil-bovine serum albumin adduct for targeted delivery. Macromolecular Bioscience
Journal Article
251, pp. 355 - 370 (2014)
Design and optimization of coupling a continuously operated reactor with simulated moving bed chromatography. Chemical Engineering Journal
Journal Article
91 (1), pp. 198 - 208 (2014)
Trichomonas vaginalis flavin reductase 1 and its role in metronidazole resistance. Molecular Microbiology
Journal Article
160, pp. 616 - 622 (2014)
A study on Nim expression in Bacteroides fragilis. Microbiology/SGM
Journal Article
32 (5), pp. 443 - 445 (2014)
Simply better glycoproteins. Nature biotechnology
Journal Article
175, pp. 36 - 42 (2014)
A platform to screen for C-type lectin receptor-binding carbohydrates and their potential for cell-specific targeting and immune modulation. Journal of Controlled Release
Journal Article
101, pp. 205 - 216 (2014)
Proteomics on porcine haptoglobin and IgG/IgA show protein species distribution and glycosylation pattern to remain similar in PCV2-SD infection. Journal of Proteomics
Journal Article
4 (32), pp. 16777 - 16781 (2014)
From systems biology to systems chemistry: metabolomic procedures enable insight into complex chemical reaction networks in water. RSC Advances
Journal Article
88 (5), pp. 2991 - 3003 (2014)
Differential adeno-associated virus serotype-specific interaction patterns with synthetic heparins and other glycans. Journal of Virology
Journal Article
45 (1), pp. 67 - 73 (2014)
The C-type lectin-like domain containing proteins Clec-39 and Clec-49 are crucial for Caenorhabditis elegans immunity against Serratia marcescens infection. Developmental and Comparative Immunology
Journal Article
24 (1), pp. 1 - 11 (2014)
Generation and analysis of draft sequences of 'Stolbur' phytoplasma from multiple displacement amplification templates. Journal of Molecular Microbiology and Biotechnology
Journal Article
15 (5), pp. 1687 - 1695 (2014)
Amphiphilic cationic ß3R3-peptides: membrane active peptidomimetics and their potential as antimicrobial agents. Biomacromolecules
Journal Article
111 (22), pp. 8173 - 8178 (2014)
Synthetic di-sulfated iduronic acid attenuates asthmatic response by blocking T-cell recruitment to inflammatory sites. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
10, pp. 1603 - 1612 (2014)
Photoswitchable precision glycooligomers and their lectin binding. Beilstein Journal of Organic Chemistry
Journal Article
136 (5), pp. 2008 - 2016 (2014)
Carbohydrate-lectin recognition of sequence-defined heteromultivalent glycooligomers. Journal of the American Chemical Society
Journal Article
15 (5), pp. 1644 - 1652 (2014)
Metal-mediated molecular self-healing in histidine-rich mussel peptides. Biomacromolecules
Journal Article
193 (7), pp. 3664 - 3675 (2014)
Differential control of mincle-dependent cord factor recognition and macrophage responses by the transcription factors C/EBPβ and HIF1α. Journal of Immunology
Journal Article
5 (5), pp. 1992 - 2002 (2014)
Synthesis of conjugation-ready zwitterionic oligosaccharides by chemoselective thioglycoside activation. Chemical Science
Journal Article
15, pp. 729 - 740 (2014)
The classical Lancefield antigen of group A Streptococcus is a virulence determinant with implications for vaccine design. Cell Host & Microbe
Journal Article
16 (20), pp. 9259 - 9265 (2014)
A comparative structural study in monolayers of GPI fragments and their binary mixtures. Physical Chemistry Chemical Physics
Journal Article
30 (18), pp. 5185 - 5192 (2014)
Versatility of a glycosylphosphatidylinositol fragment in forming highly ordered polymorphs. Langmuir
Journal Article
11 (10), pp. 588 - 600 (2014)
The role of glycosylation in IBD. Nature Reviews Gastroenterology & Hepatology
Journal Article
53 (2), pp. 557 - 561 (2014)
Continuous-flow oxidative cyanation of primary and secondary amines using singlet oxygen. Angewandte Chemie International Edition
Journal Article
50 (84), pp. 12649 - 12651 (2014)
Consecutive oxygen-based oxidations convert amines to α-cyanoepoxides. Chemical Communications
Journal Article
71 (14), pp. 2717 - 2729 (2014)
The stoichiometry of peptide-heparan sulfate binding as a determinant of uptake efficiency of cell-penetrating peptides. Cellular and Molecular Life Sciences
Journal Article
24 (5), pp. 402 - 406 (2014)
MIRAGE: the minimum information required for a glycomics experiment. Glycobiology Book (2)
2014
Book
Carbohydrates as Drugs. Springer, Cham (2014), 237 pp.
Book
Glycoscience: biology and medicine. Springer Link (2014)
Book Chapter (3)
2014
Book Chapter
Impfstoffe und Wirkstoffe - von der Grundlagenforschung zur Anwendung. In: Wie kommt das Neue in Technik und Medizin?, pp. 238 - 246 (Ed. Popp, M.). Karl Heinz Beckurts Stiftung, Garching (2014)
Book Chapter
9, 2nd edition Ed., pp. 111 - 142 (Ed. Knochel, P.). Elsevier, Amsterdam (2014)
Technology-enabled synthesis of carbohydrates. In: Comprehensive organic synthesis, Vol.
Book Chapter
1170, pp. 85 - 101 (Eds. Lutz, J.-F.; Meyer, T. Y.). Oxford University Press, USA (2014)
Recent Advances in Solid Phase Polymer Synthesis: Polyamides from Tailor-Made Building Blocks. In: Sequence-Controlled Polymers: Synthesis, Self-Assembly, and Properties, Vol. Conference Paper (1)
2014
Conference Paper
Automated oligosaccharide synthesis: from insights into fundamental glycobiology to vaccines and diagnostics. In: New Chemistry and New Opportunities from the Expanding Protein Universe, pp. 136 - 140 (Eds. Wüthrich, K.; Hilvert, D.). Proceedings of the 23rd International Solvay Conference on Chemistry, Brussels, October 16, 2013 - October 19, 2013. World Scientific, New Jersey usw. (2014)
Meeting Abstract (8)
2014
Meeting Abstract
248. 248th National Meeting of the American-Chemical-Society (ACS), San Francisco, CA, August 10, 2014 - August 14, 2014. (2014)
Druggability of mammalian C-type lectin receptors. In Abstracts of Papers of the American Chemical Society,
Meeting Abstract
24 (11), p. 1129 - 1129. Joint Meeting of the Society-for-Glycobiology (SFG) and the
Japanese-Society-of-Carbohydrate-Research (JSCR), Honolulu, HI, November 16, 2014 - November 19, 2014. Oxford University Press, Oxford (2014)
Deciphering glycan-antibody interactions: towards a carbohydrate-based vaccine against Clostridium difficile. In Glycobiology,
Meeting Abstract
24 (11), p. 1218 - 1218. Joint Meeting of the Society-for-Glycobiology (SFG) and the
Japanese-Society-of-Carbohydrate-Research (JSCR), Honolulu, HI, November 16, 2014 - November 19, 2014. (2014)
Binding of langerin/CD207 to keratan sulfate disaccharide, Gal (6SO3) β1, 4-GlcNAc (6SO3) and its triangle derivative in vitro and in vivo: possible drug targets for COPD (chronic obstructive pulmonary disease). In GLYCOBIOLOGY,
Meeting Abstract
248, CARB-72. 248th National Meeting of the American-Chemical-Society (ACS), San Francisco, CA, August 10, 2014 - August 14, 2014. Amer Chem Soc (2014)
Installation of multiple 1,2-cis glycosidic bonds by automated synthesis. In Abstracts of Papers of the American Chemical Society,
Meeting Abstract
248, CARB-47. 248th National Meeting of the American-Chemical-Society (ACS), San Francisco, CA, August 10, 2014 - August 14, 2014. Amer Chem Soc (2014)
Automated solid-phase synthesis of oligoxylans. In Abstracts of Papers of the American Chemical Society,
Meeting Abstract
24 (11), p. 1122 - 1122. Joint Meeting of the Society-for-Glycobiology (SFG) and the
Japanese-Society-of-Carbohydrate-Research (JSCR), Honolulu, HI, November 16, 2014 - November 19, 2014. Oxford University Press, Oxford (2014)
Antigenic potential of a highly conserved lipopolysaccharide inner core structure defined by synthetic approach. In Glycobiology,
Meeting Abstract
20, p. S255 - S255. John Wiley & Sons, Chichester, West Sussex, UK (2014)
Intein-based ligation stragegies for the generation of homogeneous GPI-anchored proteins. In Journal of Peptide Science,
Meeting Abstract
20 S1 Ed., pp. 47 - 48. John Wiley & Sons, Chichester, West Sussex, UK (2014)
Semi-synthesis of glycosylphosphatidylinositol anchored anchored glycopeptides and glycoproteins. In Journal of Peptide Science, Thesis - PhD (6)
2014
Thesis - PhD
Synthesis of parasite related carbohydrates and their use as probes for glycobiology. Dissertation, Freie Universität Berlin, Berlin (2014)
Thesis - PhD
Generation and Characterization of monoclonal Antibodies directed against synthetic P. falciparum Glycosylphosphatidylinositol glycans. Dissertation, Freie Universität Berlin, Berlin (2014)
Thesis - PhD
Chemical synthesis and biological evaluation of cell surface carbohydrate antigens for rational vaccine design. Dissertation, Freie Universität Berlin, Berlin (2014)
Thesis - PhD
Synthesis of sequence-defined glycooligomers for studying multivalent interactions. Dissertation, 145 pp., Freie Universität Berlin, Berlin (2014)
Thesis - PhD
Synthetis and functionalization of soft colloidal probes based in poly (ethylene glycol) as carbohydrate biosensors. Dissertation, Freie Universität Berlin, Berlin (2014)
Thesis - PhD
Sequence-defined oligo(amidoamines): synthetis, carbohydrate functionalization and biomedical applications. Dissertation, Freie Universität Berlin, Berlin (2014)
Thesis - Master (6)
2014
Thesis - Master
Automated Solid-Phase Synthesis of Plant Arabinogalactan Fragments. Master, 91 pp., Freie Universität Berlin, Berlin (2014)
Thesis - Master
Solid Phase Synthesis and Characterization of Zwitterionic Precision Polymers for Biomedical Applications. Master, 72 pp., Universität Potsdam, Potsdam (2014)
Thesis - Master
Synthesis of glycosylated Dolichol Derivatives. Master, 85 pp., Freie Universität Berlin, Berlin (2014)
Thesis - Master
Automated Solid-Phase Synthesis of Plant Arabinoxylan Fragments. Master, 85 pp., Freie Universität Berlin, Berlin (2014)
Thesis - Master
Generation of C-type lectin receptor-Fc fusion proteins and their functional characterization: SIGN-R1-hFc and Dectin-2-hFc. Master, 80 pp., Universität Potsdam, Potsdam (2014)
Thesis - Master
Precision Glycomacromolecules and their Multivalent Presentation at Soft Surfaces. Master, 84 pp., Freie Universität Berlin, Berlin (2014)
Patent (3)
2014
Patent
Synthesis of diverse glycosylphosphatidylinositol glycans from toxoplasma gondii and their application as vaccines and diagnostics. (2014)
Patent
Synthesis of diverse glycosylphosphatidylinositol glycans and glycolipids from toxoplasma gondii and their application as diagnostic markers and vaccines. (2014)
Patent
Total synthesis and immunological evaluation of saccharide moieties of the lipopolysaccharide from neisseria meningitidis. EP2766024 A1 (2014)