Journal Article (41)

  1. 2015
    Journal Article
    Aretz, J.; Rademacher, C.: Fragmentbasierte Wirkstoffentwicklung. Nachrichten aus der Chemie 63 (2), pp. 116 - 121 (2015)
  2. Journal Article
    Baek, J. Y.; Kwon, H.-W.; Myung, S. J.; Park, J. J.; Kim, M. Y.; Rathwell, D. C. K.; Jeon, H. B.; Seeberger, P. H.; Kim, K. S.: Directing effect by remote electron-withdrawing protecting groups at O-3 or O-4 position of donors in glucosylations and galactosylations. Tetrahedron: Asymmetry 71 (33), pp. 5315 - 5320 (2015)
  3. Journal Article
    Bartetzko, M.; Schuhmacher, F.; Hahm, H. S.; Seeberger, P. H.; Pfrengle, F.: Automated glycan assembly of oligosaccharides related to arabinogalactan proteins. Organic Letters 17 (17), pp. 4344 - 4347 (2015)
  4. Journal Article
    Chan, C. E.; Götze, S.; Seah, G. T.; Seeberger, P. H.; Tukvadze, N.; Wenk, M. R.; Hanson, B. J.; MacAry, P. A.: The diagnostic targeting of a carbohydrate virulence factor from M.Tuberculosis. Scientific Reports 5, 10281 (2015)
  5. Journal Article
    Correia, C. A.; Gilmore, K.; McQuade, D. T.; Seeberger, P. H.: A concise flow synthesis of Efavirenz. Angewandte Chemie International Edition 54 (16), pp. 4945 - 4948 (2015)
  6. Journal Article
    Fair, R. J.; Hahm, H. S.; Seeberger, P. H.: Combination of automated solid-phase and enzymatic oligosaccharide synthesis provides access to α(2,3)-sialylated glycans. Chemical Communications 51 (28), pp. 6183 - 6185 (2015)
  7. Journal Article
    Fluri, F.; Grünstein, D.; Cam, E.; Ungethuem, U.; Hatz, F.; Schäfer, J.; Samnick, S.; Israel, I.; Kleinschnitz, C.; Orts-Gil, G. et al.; Moch, H.; Zeis, T.; Schaeren-Wiemers, N.; Seeberger, P. H.: Fullerenols and glucosamine fullerenes reduce infarct volume and cerebral inflammation after ischemic stroke in normotensive and hypertensive rats. Experimental Neurology 265, pp. 142 - 151 (2015)
  8. Journal Article
    Frei, P.; Navarra, G.; Sager, C. P.; Silbermann, M.; Varga, N.; Wamhoff, E.-C.: Drug Discovery Summit: 11th Swiss Course on Medicinal Chemistry. ChemMedChem 10 (3), pp. 575 - 579 (2015)
  9. Journal Article
    Gerling-Driessen, U. I. M.; Mujkic-Ninnemann, N.; Ponader, D.; Schöne, D.; Hartmann, L.; Koksch, B.: Exploiting oligo(amido amine) backbones for the multivalent presentation of coiled-coil peptides. Biomacromolecules 16 (8), pp. 2394 - 2402 (2015)
  10. Journal Article
    Ghislieri, D.; Gilmore, K.; Seeberger, P. H.: Chemical assembly systems: layered control for divergent, continuous, multistep syntheses of active pharmaceutical ingredients. Angewandte Chemie International Edition 54 (2), pp. 678 - 682 (2015)
  11. Journal Article
    Götze, S.; Reinhardt, A.; Geissner, A.; Azzouz, N.; Tsai, Y.-H.; Kurucz, R.; Varon Silva, D.; Seeberger, P. H.: Investigation of the protective properties of glycosylphosphatidylinositol-based vaccine candidates in a Toxoplasma gondii mouse challenge model. Glycobiology 25 (9), pp. 984 - 991 (2015)
  12. Journal Article
    Hanashima, S.; Götze, S.; Liu, Y.; Ikeda, A.; Kojima-Aikawa, K.; Taniguchi, N.; Silva, D. V.; Feizi, T.; Seeberger, P. H.; Yamaguchi, Y.: Defining the interaction of human soluble lectin ZG16p and mycobacterial phosphatidylinositol mannosides. ChemBioChem: A European Journal of Chemical Biology 16 (10), pp. 1502 - 1511 (2015)
  13. Journal Article
    Hofmann, J.; Hahm, H. S.; Seeberger, P. H.; Pagel, K.: Identification of carbohydrate anomers using ion mobility-mass spectrometry. Nature 526 (7572), pp. 241 - 244 (2015)
  14. Journal Article
    Horváth, Z.; Horosanskaia, E.; Lee, J. W.; Lorenz, H.; Gilmore, K.; Seeberger, P. H.; Seidel-Morgenstern, A.: Recovery of artemisinin from a complex reaction mixture using continuous chromatography and crystallization. Organic Process Research & Development 19 (6), pp. 624 - 634 (2015)
  15. Journal Article
    Lai, C.-H.; Hahm, H. S.; Liang, C.-F.; Seeberger, P. H.: Automated solid-phase synthesis of oligosaccharides containing sialic acids. Beilstein Journal of Organic Chemistry 11, pp. 617 - 621 (2015)
  16. Journal Article
    LaRock, C.; Döhrmann, S.; Todd, J.; Corriden, R.; Olson, J.; Johannssen, T.; Lepenies, B.; Gallo, R. L.; Ghosh, P.; Nizet, V.: Group A Streptococcal M1 Protein Sequesters Cathelicidin to Evade Innate Immune Killing. Cell Host & Microbe 18 (4), pp. 471 - 477 (2015)
  17. Journal Article
    Lee, C.-U.; Hahne, G.; Hanske, J.; Bange, T.; Bier, D.; Rademacher, C.; Hennig, S.; Grossmann, T.: Redox Modulation of PTEN Phosphatase Activity by Hydrogen Peroxide and Bisperoxidovanadium Complexes. Angewandte Chemie, International Edition 54, pp. 13796 - 13800 (2015)
  18. Journal Article
    Lee, C.-U.; Hahne, G.; Hanske, J.; Bange, T.; Bier, D.; Rademacher, C.; Hennig, S.; Grossmann, T.: Redox-Modulation der PTEN-Phosphataseaktivität durch Wasserstoffperoxid und Bisperoxidovanadium-Komplexe. Angewandte Chemie 127 (46), pp. 14001 - 14005 (2015)
  19. Journal Article
    Lightfoot, Y. L.; Selle, K.; Yang, T.; Goh, Y. J.; Sahay, B.; Zadeh, M.; Owen, J. L.; Colliou, N.; Li, E.; Johannssen, T. et al.; Lepenies, B.; Klaenhammer, T. R.; Mohamadzadeh, M.: SIGNR3-dependent immune regulation by Lactobacillus acidophilus surface layer protein A in colitis. The EMBO Journal 34 (7), pp. 881 - 895 (2015)
  20. Journal Article
    Manzano-Lopez, J.; Perez-Linero, A. M.; Aguilera-Romero, A.; Martin, M. E.; Okano, T.; Silva, D. V.; Seeberger, P. H.; Riezman, H.; Funato, K.; Goder, V. et al.; Wellinger, R. E.; Muniz, M.: COPII coat composition is actively regulated by luminal cargo maturation. Current Biology 25 (2), pp. 152 - 162 (2015)
  21. Journal Article
    Matthies, S.; McQuade, D. T.; Seeberger, P. H.: Homogeneous gold-catalyzed glycosylations in continuous flow. Organic Letters 17 (15), pp. 3670 - 3673 (2015)
  22. Journal Article
    Matthies, S.; Stallforth, P.; Seeberger, P. H.: Total synthesis of legionaminic acid as basis for serological studies. Journal of the American Chemical Society 137 (8), pp. 2848 - 2851 (2015)
  23. Journal Article
    Moelling, K.; Bröcker, F.: The reverse transcriptase-RNase H: from viruses to antiviral defense. DNA Habitats and Their RNA Inhabitants 1341, pp. 126 - 135 (2015)
  24. Journal Article
    Nobuta, T.; Xiao, G.; Ghislieri, D.; Gilmore, K.; Seeberger, P. H.; Seeberger, P. H.: Continuous and convergent access to vicinyl amino alcohols. Chemical Communications 51, pp. 15133 - 15136 (2015)
  25. Journal Article
    Ostrop, J.; Jozefowski, K.; Zimmermann, S.; Hofmann, K.; Strasser, E.; Lepenies, B.; Lang, R.: Contribution of MINCLE-SYK Signaling to Activation of Primary Human APCs by Mycobacterial Cord Factor and the Novel Adjuvant TDB. Journal of Immunology 195 (5), pp. 2417 - 2428 (2015)
  26. Journal Article
    Pereira, C. L.; Geißner, A.; Chakkumkal, A.; Seeberger, P. H.: Chemical synthesis elucidates the immunological importance of a pyruvate modification in the capsular polysaccharide of Streptococcus pneumoniae serotype 4. Angewandte Chemie, International Edition in English 54, pp. 10016 - 10019 (2015)
  27. Journal Article
    Pereira, C. L.; Geißner, A.; Chakkumkal, A.; Seeberger, P. H.: Synthetische Oligosaccharide belegen die immunologische Bedeutung der Pyruvatmodifikation im Kapselpolysaccharid von Serotyp 4 Streptococcus pneumoniae. Angewandte Chemie 127 (34), pp. 10154 - 10157 (2015)
  28. Journal Article
    Qi, Z.; Bharate, P.; Lai, C.-H.; Ziem, B.; Böttcher, C.; Schulz, A.; Beckert, F.; Hatting, B.; Mülhaupt, R.; Seeberger, P. H. et al.; Haag, R.: Multivalency at interfaces: supramolecular carbohydrate-functionalized graphene derivatives for bacterial capture, release, and disinfection. Nano Letters 15 (9), pp. 6051 - 6057 (2015)
  29. Journal Article
    Rabes, A.; Zimmermann, S.; Reppe, K.; Lang, R.; Seeberger, P. H.; Suttorp, N.; Witzenrath, M.; Lepenies, B.; Opitz, B.: The C-type lectin receptor Mincle binds to Streptococcus pneumoniae but plays a limited tole in the anti-pneumococcal innate immune response. PLoS One 10 (2), UNSP e0117022 (2015)
  30. Journal Article
    Redy-Keisar, O.; Huth, K.; Vogel, U.; Lepenies, B.; Seeberger, P. H.; Shabat, D.: Enhancement of fluorescent properties of near-infrared dyes using clickable oligoglycerol dendrons. Organic & Biomolecular Chemistry 16 (13), pp. 4727 - 4732 (2015)
  31. Journal Article
    Reinhardt, A.; Yang, Y.; Claus, H.; Pereira, C. L.; Cox, A. D.; Vogel, U.; Anish, C.; Seeberger, P. H.: Antigenic potential of a highly conserved Neisseria meningitidis lipopolysaccharide inner core structure defined by chemical synthesis. Chemistry & Biology 22 (1), pp. 38 - 49 (2015)
  32. Journal Article
    Schmidt, D.; Schuhmacher, F.; Geissner, A.; Seeberger, P. H.; Pfrengle, F.: Automated synthesis of arabinoxylan-aligosaccharides enables characterization of antibodies that recognize plant cell wall glycans. Chemistry – A European Journal 21 (15), pp. 5709 - 5713 (2015)
  33. Journal Article
    Schmidt, S.; Wang, H.; Pussak, D.; Mosca, S.; Hartmann, L.: Probing multivalency in ligand-receptor-mediated adhesion of soft, biomimetic interfaces. Beilstein Journal of Organic Chemistry 11, pp. 720 - 729 (2015)
  34. Journal Article
    Seeberger, P. H.: The logic of automated glycan assembly. Accounts of Chemical Research 48 (5), pp. 1450 - 1463 (2015)
  35. Journal Article
    Stavenhagen, K.; Kolarich, D.; Wuhrer, M.: Clinical Glycomics Employing Graphitized Carbon Liquid Chromatography-Mass Spectrometry. Chromatographia 78 (5-6), pp. 307 - 320 (2015)
  36. Journal Article
    Täuber, K.; Lepenies, B.; Yuan, J.: Polyvinylpyridinium-type gradient porous membranes: synthesis, actuation and intrinsic cell growth inhibition. Polymer Chemistry 6 (27), pp. 4855 - 4858 (2015)
  37. Journal Article
    Ushakov, D. B.; Plutschack, M. B.; Gilmore, K.; Seeberger, P. H.: Factors influencing the regioselectivity of the oxidation of asymmetric secondary amines with singlet oxygen. Chemistry – A European Journal 21 (17), pp. 6528 - 6534 (2015)
  38. Journal Article
    Vukelić, S.; Ushakov, D. B.; Gilmore, K.; Koksch, B.; Seeberger, P. H.: Flow synthesis of fluorinated α-amino acids. European Journal of Organic Chemistry 2015 (14), pp. 3036 - 3039 (2015)
  39. Journal Article
    Wieczorek, S.; Vigne, S.; Masini, T.; Ponader, D.; Hartmann, L.; Hirsch, A. K. H.; Börner, H. G.: Combinatorial Screening for Specific Drug Solubilizers with Switchable Release Profiles. Macromolecular Bioscience 15 (1), pp. 82 - 89 (2015)
  40. Journal Article
    Zacco, E.; Chakkumkal, A.; Martin, C. E.; von Berlepsch, H.; Brandenburg, E.; Seeberger, P. H.; Koksch, B.: A self-assembling peptide scaffold for the multivalent presentation of antigens. Biomacromolecules 16 (7), pp. 2188 - 2197 (2015)
  41. Journal Article
    Zacco, E.; Hütter, J.; Heier, J. L.; Mortier, J.; Seeberger, P. H.; Lepenies, B.; Koksch, B.: Tailored presentation of carbohydrates on a coiled coil-based scaffold for asialoglycoprotein receptor targeting. ACS Chemical Biology 10 (9), pp. 2065 - 2072 (2015)

Book (1)

  1. 2015
    Lepenies, B. (Ed.): Carbohydrate-Based Vaccines. Springer Science+Business Media, New York (2015), 255 pp.

Book Chapter (5)

  1. 2015
    Book Chapter
    Bröcker, F.; Chakkumkal, A.; Seeberger, P. H.: Generation of monoclonal antibodies against defined oligosaccharide antigens. In: Carbohydrate-Based Vaccines, pp. 57 - 80 (Ed. Lepenies, B.). Springer Science+Business Media, New York (2015)
  2. Book Chapter
    Hütter, J.; Lepenies, B.: Carbohydrate-Based Vaccines: An Overview. In: Carbohydrate-Based Vaccines, pp. 1 - 10 (Ed. Lepenies, B.). Springer Science+Business Media, New York (2015)
  3. Book Chapter
    Johannssen, T.; Lepenies, B.: Identification and Characterization of Carbohydrate-Based Adjuvants. In: Carbohydrate-Based Vaccines, pp. 173 - 187 (Ed. Lepenies, B.). Springer Science+Business Media, New York (2015)
  4. Book Chapter
    Kolarich, D.; Windwarder, M.; Alagesan, K.; Altmann, F.: Isomer-Specific Analysis of Released N-Glycans by LC-ESI MS/MS with Porous Graphitized Carbon. In: Glyco-Engineering. Methods in Molecular Biology, Vol. 1321, Vol. 1321, pp. 427 - 435 (Ed. Castilho, A.). Humana Press, Clifton, N.J. (2015)
  5. Book Chapter
    Zimmermann, S.; Lepenies, B.: Glycans as Vaccine Antigens and Adjuvants: Immunological Considerations. In: Carbohydrate-Based Vaccines, pp. 11 - 26 (Ed. Lepenies, B.). Springer Science+Business Media, New York (2015)

Meeting Abstract (4)

  1. 2015
    Meeting Abstract
    Alagesan, K.; Silva, D. V.; Seeberger, P. H.; Kolarich, D.: A novel, ultrasensitive approach for quantitative carbohydrate composition and linkage analysis using LC-ESI ion trap tandem mass spectrometry. In Journal of Mass Spectrometry, 50 (1), pp. 3 - 4. 20th International Spectrometry Conference 2014, Geneva, August 24, 2014 - August 29, 2014. Wiley, Chichester, England (2015)
  2. Meeting Abstract
    Carillo, M. A.; Silva, D. V.: Semi-synthesis and Evaluation of Parasitic GPI-Anchored Proteins. In Protein Science, 24 Special Issue Ed., PI-074, pp. 217 - 218. 29th Annual Symposium of the Protein-Society, Barcelona, SPAIN, July 22, 2015 - July 25, 2015. Cambridge University Press, New York, N.Y. (2015)
  3. Meeting Abstract
    Schulze, J.; Wamhoff, E.-C.; Rademacher, C.: Towards small molecule-based targeted delivery to immune cells. In FEBS Journal, 282 Supplement 1 Ed., P15-027, p. 245 - 245. 40th Congress of the Federation-of-European-Biochemical-Societies (FEBS) - The Biochemical Basis of Life, Berlin, Germany, July 04, 2015 - July 09, 2015. Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies, Oxford, UK (2015)
  4. Meeting Abstract
    Valerius, T.; Lohse, S.; Meyer, S.; Jansen, M. J.H.; Meulenbroek, L. A.P.; Nederend, M.; Möginger, U.; Kretschmer, A.; Klausz, K.; Derer, S. et al.; Sondermann, P.; Kolarich, D.; Peipp, M.; Leusen, J. H.W.; Gramatzki, M.: Pharmacokinetics and myeloid effector cell engagement of an engineered IgA antibody against the epidermal growth factor receptor. In Journal of Clinical Oncology, 33 supplement Ed., abstract 3037. 2015 ASCO Annual Meeting. Grune & Stratton, New York, NY (2015)

Thesis - PhD (5)

  1. 2015
    Thesis - PhD
    Hütter, J.: Carbohydrate-mediated cell targeting and the role of C-type lectin receptors in autoimmunity. Dissertation, Freie Universität Berlin, Berlin (2015)
  2. Thesis - PhD
    Matthies, S.: Total Synthesis of Complex Biomolecules: De Novo Synthesis of Legionaminic Acids and Continuous Flow Glycosylations. Dissertation, Freie Universität Berlin, Berlin (2015)
  3. Thesis - PhD
    Monnanda, B. P.: Host Responses to Presentation of Particulate Virulence Factors of Bacteria and Parasites. Dissertation, Freie Universität Berlin, Berlin (2015)
  4. Thesis - PhD
    Reinhardt, A.: Immunological Relevance of Conserved Lipopolysaccharide Inner Core Structures of Pathogenic Gram-Negative Bacteria. Dissertation, Freie Universität Berlin, Berlin (2015)
  5. Thesis - PhD
    Schumann, B.: Synthesis and Immunological Evaluation of Oligosaccharide-Antigens as Vaccine Candidates for Streptococcus pneumoniae Serotypes 1 and 8. Dissertation, Freie Universität Berlin, Berlin (2015)

Editorial (1)

  1. 2015
    Hicks, M. G.; Seeberger, P. H.; Seeberger, P. H.: The Beilstein Journal of Organic Chemistry and the changing face of scientific publishing. Beilstein Journal of Organic Chemistry 11, pp. 2242 - 2244 (2015)

Patent (3)

  1. 2015
    Kopetzki, D.; McQuade, D. T.; Seeberger, P. H.; Gilmore, K.: Method and apparatus for the synthesis of dihydroartemisinin and artemisinin derivatives. WO2015007693 (2015)
  2. Patent
    Seeberger, P. H.; Pereira, C. L.: Synthetic vaccines against Streptococcus pneumoniae. (2015)
  3. Patent
    Seeberger, P. H.; Pereira, C. L.; Chakkumkal, A.; Schumann, B.: Synthetic vaccines against Streptococcus pneumoniae type 1. (2015)
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