Publications
Journal Article (57)
2016
Journal Article
1860 (8), pp. 1583 - 1595 (2016)
The promise of protein glycosylation for personalised medicine. Biochimica et Biophysica Acta (BBA) - General Subjects
Journal Article
52 (58), pp. 9067 - 9070 (2016)
Chemical fragment arrays for rapid druggability assessment. Chemical Communications
Journal Article
94 (11), pp. 920 - 926 (2016)
Fragment-screening of N-acetylmannosamine kinase reveals non-carbohydrate inhibitors. Canadian Journal of Chemistry
Journal Article
26 (5), pp. 532 - 539 (2016)
Complement Factor H and Simian Virus 40 bind the GM1 ganglioside in distinct conformations. Glycobiology
Journal Article
7, 25 (2016)
The intron-enriched HERV-K(HML-10) family suppresses apoptosis, an indicator of malignant transformation. Mobile DNA
Journal Article
2 (1), a000448 (2016)
Long-term changes of bacterial and viral compositions in the intestine of a recovered Clostridium difficile patient after fecal microbiota transplantation. Cold Spring Harbor Molecular Case Studies
Journal Article
23 (8), pp. 1014 - 1022 (2016)
Synthetic lipoteichoic acid glycans are potential vaccine candidates to protect from Clostridium difficile infections. Cell Chemical Biology
Journal Article
7, 11224 (2016)
Multivalent display of minimal Clostridium difficile glycan epitopes mimics antigenic properties of larger glycans. Nature Communications
Journal Article
1372 (1), pp. 29 - 41 (2016)
Long-term microbiota and virome in a Zürich patient after fecal transplantation against Clostridium difficile infection. Annals of the New York Academy of Sciences
Journal Article
11 (8), pp. 2347 - 2356 (2016)
Influence of core β-1,2-xylosylation on glycoprotein recognition by murine C-type lectin receptors and its impact on dendritic cell targeting. ACS Chemical Biology
Journal Article
35 (13), pp. 1619 - 1631 (2016)
Preventing E-cadherin aberrant N-glycosylation at Asn-554 improves its critical function in gastric cancer. Oncogene
Journal Article
81 (19), pp. 9415 - 9421 (2016)
Synthesis of α-nitro carbonyls via nitrations in flow. The Journal of Organic Chemistry
Journal Article
14 (1), pp. 309 - 313 (2016)
Automated glycan assembly of xyloglucan oligosaccharides. Organic & Biomolecular Chemistry
Journal Article
116 (4), pp. 1693 - 1752 (2016)
Carbohydrates in supramolecular chemistry. Chemical Reviews
Journal Article
141 (18), pp. 5412 - 5416 (2016)
Integrated on-chip mass spectrometry reaction monitoring in microfluidic devices containing porous polymer monolithic columns. Analyst
Journal Article
11 (2), pp. 335 - 344 (2016)
Deciphering antigenic determinants of Streptococcus pneumoniae serotype 4 capsular polysaccharide using synthetic oligosaccharides. ACS Chemical Biology
Journal Article
9 (1), pp. 223 - 247 (2016)
Glycan arrays: from basic biochemical research to bioanalytical and biomedical applications. Annual Review of Analytical Chemistry
Journal Article
6 (5), pp. 487 - 514 (2016)
The Baldwin rules: revised and extended. Wiley Interdisciplinary Reviews: Computational Molecular Science
Journal Article
7, 12482 (2016)
Automated assembly of oligosaccharides containing multiple cis-glycosidic linkages. Nature Communications
Journal Article
81 (14), pp. 5866 - 5877 (2016)
Automated glycan assembly of complex oligosaccharides related to blood group determinants. The Journal of Organic Chemistry
Journal Article
138 (37), pp. 12176 - 12186 (2016)
Intradomain allosteric network modulates calcium affinity of the C-Type lectin receptor langerin. Journal of the American Chemical Society
Journal Article
52 (23), pp. 4381 - 4384 (2016)
Distinguishing N-acetylneuraminic acid linkage isomers on glycopeptides by ion mobility-mass spectrometry. Chemical Communications
Journal Article
27 (3), pp. 507 - 519 (2016)
The art of destruction: optimizing collision energies in quadrupole-time of flight (Q-TOF) instruments for glycopeptide-based glycoproteomics. Journal of the American Society for Mass Spectrometry
Journal Article
14 (37), pp. 8648 - 8658 (2016)
Using carbohydrate-based biomaterials as scaffolds to control human stem cell fate. Organic & Biomolecular Chemistry
Journal Article
22 (6), pp. 405 - 418 (2016)
Trehalose diester glycolipids are superior to the monoesters in binding to Mincle, activation of macrophages in vitro and adjuvant activity in vivo. Innate Immunity
Journal Article
33 (3), pp. 405 - 415 (2016)
Comparison of analytical methods for profiling N- and O-linked glycans from cultured cell lines. Glycoconjugate Journal
Journal Article
26 (1), pp. 74 - 87 (2016)
Flagellin glycosylation in Paenibacillus alvei CCM 2051T. Glycobiology
Journal Article
14 (33), pp. 7933 - 7948 (2016)
Development and optimization of a competitive binding assay for the galactophilic low affinity lectin LecA from Pseudomonas aeruginosa. Organic & Biomolecular Chemistry
Journal Article
8 (42), pp. 18098 - 18104 (2016)
Precise redox-sensitive cleavage sites for improved bioactivity of siRNA lipopolyplexes. Nanoscale
Journal Article
33 (3), pp. 259 - 260 (2016)
Glycomics & glycoproteomics in glycoconjugate journal. Glycoconjugate Journal
Journal Article
16 (1), pp. 807 - 811 (2016)
Analysis of carbohydrate-carbohydrate interactions using sugar-functionalized silicon nanoparticles for cell imaging. Nano Letters
Journal Article
52 (8), pp. 1586 - 1589 (2016)
Synthesis of glycosylphosphatidylinositol (GPI)-anchor glycolipids bearing unsaturated lipids. Chemical Communications
Journal Article
76 (2), pp. 403 - 417 (2016)
An anti-EGFR IgA that displays improved pharmacokinetics and myeloid effector cell engagement in vivo. Cancer Research
Journal Article
51, pp. 31 - 55 (2016)
Emerging roles of protein mannosylation in inflammation and infection. Molecular Aspects of Medicine
Journal Article
27 (1), pp. 80 - 86 (2016)
Saturation transfer difference nuclear magnetic resonance titrations reveal complex multistep-binding of l-fucose to norovirus particles. Glycobiology
Journal Article
213 (1), pp. 80 - 89 (2016)
Human C1-inhibitor suppresses malaria parasite invasion and cytoadhesion via binding to parasite glycosylphosphatidylinositol and host cell receptors. The Journal of Infectious Diseases
Journal Article
1860 (8), pp. 1795 - 1808 (2016)
Glycomic analysis of gastric carcinoma cells discloses glycans as modulators of RON receptor tyrosine kinase activation in cancer. Biochimica et Biophysica Acta (BBA) - General Subjects
Journal Article
7, pp. 814 - 833 (2016)
Glycomic and sialoproteomic data of gastric carcinoma cells overexpressing ST3GAL4. Data in Brief
Journal Article
6 (2), pp. 94 - 100 (2016)
Flow-based surface decoration of microparticles with titania and other transition metal oxide nanoparticles. Journal of Flow Chemistry
Journal Article
6, 20488 (2016)
Cross Reactive Material 197 glycoconjugate vaccines contain privileged conjugation sites. Scientific Reports
Journal Article
6 (4), e1251380 (2016)
Fecal microbiota transplantation to fight Clostridium difficile infections and other intestinal diseases. Bacteriophage
Journal Article
23 (11), pp. 1407 - 1416 (2016)
A semi-synthetic oligosaccharide conjugate vaccine candidate confers protection against Streptococcus pneumoniae serotype 3 infection. Cell Chemical Biology
Journal Article
57, pp. 43 - 76 (2016)
Organic photoredox chemistry in flow. Topics in Organometallic Chemistry
Journal Article
195 (3), pp. 387 - 395 (2016)
Structure binding relationship of human surfactant protein D and various lipopolysaccharide inner core structures. Journal of Structural Biology
Journal Article
17 (6), pp. 1959 - 1968 (2016)
Photosensitive peptidomimetic for light-controlled, reversible DNA compaction. Biomacromolecules
Journal Article
55 (46), pp. 14431 - 14434 (2016)
Nucleophile-directed stereocontrol over glycosylations using geminal-difluorinated nucleophiles. Angewandte Chemie International Edition
Journal Article
32 (10), pp. 2436 - 2444 (2016)
Impact of structural differences in galactocerebrosides on the behavior of 2D monolayers. Langmuir
Journal Article
26 (9), pp. 907 - 910 (2016)
The minimum information required for a glycomics experiment (MIRAGE) project: sample preparation guidelines for reliable reporting of glycomics datasets. Glycobiology
Journal Article
7, pp. 1278 - 1283 (2016)
Straightforward and robust synthesis of monodisperse surface-functionalized gold nanoclusters. Beilstein Journal of Nanotechnology
Journal Article
7, 13507 (2016)
Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease. Nature Communications
Journal Article
22 (38), pp. 13451 - 13454 (2016)
A sustainable, semi-continuous flow synthesis of hydantoins. Chemistry – A European Journal
Journal Article
11 (9), pp. 2407 - 2413 (2016)
19F NMR-guided design of glycomimetic Langerin ligands. ACS Chemical Biology
Journal Article
12, pp. 1440 - 1446 (2016)
Automated glycan assembly of a S. pneumoniae serotype 3 CPS antigen. Beilstein Journal of Organic Chemistry
Journal Article
52 (66), pp. 10187 - 10189 (2016)
A traceless photocleavable linker for the automated glycan assembly of carbohydrates with free reducing ends. Chemical Communications
Journal Article
492, pp. 118 - 129 (2016)
Genetic characterization of an adapted pandemic 2009 H1N1 influenza virus that reveals improved replication rates in human lung epithelial cells. Virology
Journal Article
22 (43), pp. 15216 - 15221 (2016)
Tumour-targeted drug delivery with mannose-functionalized nanoparticles self-assembled from amphiphilic β-cyclodextrins. Chemistry – A European Journal
Journal Article
8 (49), pp. 33405 - 33411 (2016)
Targeted photodynamic killing of breast cancer cells employing heptamannosylated β-cyclodextrin-mediated nanoparticle formation of an adamantane-functionalized BODIPY photosensitizer. ACS Applied Materials and Interfaces Book Chapter (2)
2016
Book Chapter
Automated oligosaccharide synthesis: techniques and applications. In: Glycochemical Synthesis: Strategies and Applications, pp. 189 - 204 (Eds. Hung, S.-C.; Zulueta, M. M. L.). John Wiley & Sons, Hoboken, New Jersey (2016)
Book Chapter
232, pp. 73 - 89. Springer, Switzerland (2016)
High-throughput synthesis of diverse compound collections for lead discovery and optimization. In: Handbook of Experimental Pharmacology, Vol. Meeting Abstract (4)
2016
Meeting Abstract
46 S1 Ed., 647, pp. 669 - 670. ICI 2016 International Congress of Immunology, Melbourne, Australia , August 21, 2016 - August 26, 2016. Wiley-VCH, Weinheim (2016)
Dissecting the functional effector responses mediated by human IgG subclasses against Plasmodium falciparum merozoites. In European Journal of Immunology,
Meeting Abstract
39 (Suppl. 3), P276, pp. 83 - 84. Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, Leipzig, October 14, 2016 - October 18, 2016. Karger, Basel, Schweiz (2016)
Glyco- and Fc engineering of IgA antibodies for cancer immunotherapy improved pharmacokinetics & myeloid effector cell engagement. In Oncology Research and Treatment,
Meeting Abstract
69, 440, p. S144. Pergamon, Oxford, UK (2016)
Improvement of pharmacokinetics and myeloid effector cell engagement in vivo by Fc-engineering of IgA antibody against the epidermal growth factor receptor. In European Journal of Cancer,
Meeting Abstract
70 (S 01), P489. 57. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V., Leipzig, March 02, 2016 - March 05, 2016. (2016)
Passive Immunisierung mit dem monoklonalen Antikörper 1H8 schützt Mäuse vor pneumogener Sepsis. In Pneumologie, Thesis - PhD (6)
2016
Thesis - PhD
The mass spectrometry toolkit for glycoprotein characterisation: development of novel analytical methods and technologies for glycomics and glycoproteomics. Dissertation, Freie Universität Berlin, Berlin (2016)
Thesis - PhD
Fragment-based design of novel lectin ligands. Dissertation, 251 pp., Freie Universität Berlin, Berlin (2016)
Thesis - PhD
Towards vaccines and therapeutic antibodies against Clostridium difficile based on synthetic glycans. Dissertation, 155 pp., Freie Universität Berlin, Berlin (2016)
Thesis - PhD
Investigation of the structural basis of ligand recognition of the C-type lectin receptor Langerin. Dissertation, 170 pp., Freie Universität Berlin, Berlin (2016)
Thesis - PhD
Assessing the influence of different structural features on multivalent thermodynamics and kinetics of precision glycomacromolecules. Dissertation, Freie Universität, Berlin (2016)
Thesis - PhD
Synthesis of fluorinated amino acids and their derivatives in flow. Dissertation, 192 pp., Freie Universität, Berlin (2016)
Report (1)
2016
Report
17). (2016)
ECBS & ICBS 2015 Joint Meeting: Bringing Chemistry to Life (ChemBioChem: A European Journal of Chemical Biology, Patent (5)
2016
Patent
Vaccines against Streptococcus pneumoniae serotype 5. WO2016198170 (2016)
Patent
Antibodies for prevention and treatment of diseases caused by Clostridium difficile. (2016)
Patent
Vaccines against Streptococcus pneumoniae serotype 4. EP3230297 (2016)
Patent
Synthetic vaccines against Streptococcus pneumoniae serotype 8. (2016)
Patent
Vaccine against carbapenem-resistant klebsiella pneumoniae. EP3274358 (2016)