Publications

Journal Article (46)

2018
Journal Article
Aretz, J.; Anumala, U. R.; Fuchsberger, F. F.; Molavi, N.; Ziebart, N.; Zhang, H.; Nazaré, M.; Rademacher, C.: Allosteric inhibition of a mammalian lectin. Journal of the American Chemical Society 140 (44), pp. 14915 - 14925 (2018)
Journal Article
Atwater, J.; Mattes, D. S.; Streit, B.; von Bojničić‐Kninski, C.; Löffler, F. F.; Breitling, F.; Fuchs, H.; Hirtz, M.: Combinatorial synthesis of macromolecular arrays by microchannel cantilever spotting (µCS). Advanced Materials 30 (31), 1801632 (2018)
Journal Article
Baek, J. Y.; Geissner, A.; Rathwell, D. C. K.; Meierhofer, D.; Pereira, C. L.; Seeberger, P. H.: A modular synthetic route to size-defined immunogenic Haemophilus influenzae b antigens is key to the identification of an octasaccharide lead vaccine candidate. Chemical Science 9 (5), pp. 1279 - 1288 (2018)
Journal Article
Blaum, B. S.; Neu, U.; Peters, T.; Stehle, T.: Spin ballet for sweet encounters: saturation-transfer difference NMR and X-ray crystallography complement each other in the elucidation of protein–glycan interactions. Acta Crystallographie Section F Structural Biology and Crystallization Communications F74, pp. 451 - 462 (2018)
Journal Article
Bröcker, F.; Götze, S.; Hudon, J.; Rathwell, D. C. K.; Pereira, C. L.; Stallforth, P.; Chakkumkal, A.; Seeberger, P. H.: Synthesis, liposomal formulation, and immunological evaluation of a minimalistic carbohydrate-α-GalCer vaccine candidate. Journal of Medicinal Chemistry 61 (11), pp. 4918 - 4927 (2018)
Journal Article
Chatterjee, S.; Moon, S.; Hentschel, F.; Gilmore, K.; Seeberger, P. H.: An empirical understanding of the glycosylation reaction. Journal of the American Chemical Society 140 (38), pp. 11942 - 11953 (2018)
Journal Article
Chen, C.; Ao, L.; Wu, Y.-T.; Cifliku, V.; Cardoso Dos Santos, M.; Bourrier, E.; Delbianco, M.; Parker, D.; Zwier, J.; Huang, L. et al.; Hildebrandt, N.: Single-nanoparticle cell barcoding by tunable FRET from lanthanides to quantum dots. Angewandte Chemie International Edition 57 (41), pp. 13686 - 13690 (2018)
Journal Article
Delbianco, M.; Kononov, A.; Poveda, A.; Yu, Y.; Diercks, T.; Jiménez-Barbero, J.; Seeberger, P. H.: Well-defined oligo- and polysaccharides as ideal probes for structural studies. Journal of the American Chemical Society 140 (16), pp. 5421 - 5426 (2018)
Journal Article
Devulapally, P. R.; Bürger, J.; Mielke, T.; Konthur, Z.; Lehrach, H.; Yaspo, M.-L.; Glökler, J.; Warnatz, H.-J.: Simple paired heavy- and light-chain antibody repertoire sequencing using endoplasmic reticulum microsomes. Genome Medicine 10, 34 (2018)
Journal Article
Diago-Navarro, E.; Motley, M. P.; Ruiz-Peréz, G.; Yu, W.; Austin, J.; Seco, B. M. S.; Xiao, G.; Chikhalya, A.; Seeberger, P. H.; Fries, B. C.: Novel, broadly reactive anticapsular antibodies against carbapenem-resistant Klebsiella pneumoniae protect from infection. mBio 9 (2), e00091-18 (2018)
Journal Article
Ditgen, D.; Anandarajah, E.M.; Reinhard, A.; Younis, A.E.; Witt, S.; Hansmann, J.; Lorenz, E.; García-Hernández, M.; Paclik, D.; Soblik, H. et al.; Jolodar, A.; Seeberger, P. H.; Liebau, E.; Brattig, N.W.: Comparative characterization of two galectins excreted-secreted from intestine-dwelling parasitic versus free-living females of the soil-transmitted nematode Strongyloides. Molecular and Biochemical Parasitology 225, pp. 73 - 83 (2018)
Journal Article
Doyle, E.; Stavenhagen, K.; Kolarich, D.; Sommerhoff, C.; Maurer, M.; Metz, M.: Human mast cell tryptase is a potential treatment for snakebite envenoming across multiple snake species. Frontiers in Immunology 9, 1532 (2018)
Journal Article
Ferrari, C.; Proost, S.; Ruprecht, C.; Mutwil, M.: PhytoNet: comparative co-expression network analyses across phytoplankton and land plants. Nucleic Acids Research 46 (W1), pp. W76 - W83 (2018)
Journal Article
Fühner, V.; Heine, P.; Helmsing, S.; Goy, S.; Heidepriem, J.; Löffler, F. F.; Dübel, S.; Gerhard, R.; Hust, M.: Development of neutralizing and non-neutralizing antibodies targeting known and novel epitopes of TcdB of Clostridioides difficile. Frontiers in Microbiology 9, 2908 (2018)
Journal Article
Gerlach, D.; Guo, Y.; De Castro, C.; Kim, S.-H.; Schlatterer, K.; Xu, F.-F.; Pereira, C. L.; Seeberger, P. H.; Ali, S.; Codée, J. et al.; Sirisarn, W.; Schulte, B.; Wolz, C.; Larsen, J.; Molinaro, A.; Lee, B. L.; Xia, G.; Stehle, T.; Peschel, A.: Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity. Nature 563 (7733), pp. 705 - 709 (2018)
Journal Article
Giglio, V.; Varela-Aramburu, S.; Travaglini, L.; Fiorini, F.; Seeberger, P. H.; Maggini, L.; Cola, L. D.: Reshaping silica particles: mesoporous nanodiscs for bimodal delivery and improved cellular uptake. Chemical Engineering Journal 340, pp. 148 - 154 (2018)
Journal Article
Grube, M.; Bo-Young, L.; Garg, M.; Michel, D.; Malik, A.; Vilotijevic, I.; Seeberger, P. H.; Varon Silva, D.: Synthesis of galactosylated glycosylphosphatidylinositol derivatives from Trypanosoma brucei. Chemistry – A European Journal 24 (13), pp. 3271 - 3282 (2018)
Journal Article
Hu, J.; Wei, P.; Seeberger, P. H.; Yin, J.: Mannose-functionalized nanoscaffolds for targeted delivery in biomedical applications. Chemistry – An Asian Journal 13 (22), pp. 3448 - 3459 (2018)
Journal Article
Kaplonek, P.; Khan, N.; Reppe, K.; Schumann, B.; Emmadi, M.; Lisboa, M. P.; Xu, F.-F.; Calow, A. D. J.; Parameswarappa, S. G.; Witzenrath, M. et al.; Pereira, C. L.; Seeberger, P. H.: Improving vaccines against Streptococcus pneumoniae using synthetic glycans. Proceedings of the National Academy of Sciences of the United States of America 115 (52), pp. 13353 - 13358 (2018)
Journal Article
Lama, S.; Schmidt, J.; Malik, A.; Walczak, R.; Varon Silva, D.; Völkel, A.; Oschatz, M.: Modification of salt-templated carbon surface chemistry for efficient oxidation of glucose with supported gold catalysts. ChemCatChem 10 (11), pp. 2458 - 2465 (2018)
Journal Article
Mattes, D. S.; Rentschler, S.; Foertsch, T. C.; Münch, S. W.; Löffler, F. F.; Nesterov-Mueller, A.; Bräse, S.; Breitling, F.: A trifunctional linker for purified 3D assembled peptide structure arrays. Small Methods 2 (2), 1700205 (2018)
Journal Article
Menova, P.; Sella, M.; Sellrie, K.; Pereira, C. L.; Seeberger, P. H.: Identification of the minimal glycotope of Streptococcus pneumoniae 7F capsular polysaccharide using synthetic oligosaccharides. Chemistry – A European Journal 24 (16), pp. 4181 - 4187 (2018)
Journal Article
Möginger, U.; Grunewald, S.; Hennig, R.; Kuo, C.-W.; Schirmeister, F.; Voth, H.; Rapp, E.; Khoo, K.-H.; Seeberger, P. H.; Simon, J.-C. et al.; Kolarich, D.: Alterations of the human skin N- and O-glycome in basal- and squamous cell carcinoma. Frontiers in Oncology 8, 70 (2018)
Journal Article
Mucha, E.; Lettow, M.; Marianski, M.; Thomas, D. A.; Struwe, W. B.; Harvey, D. J.; Meijer, G.; Seeberger, P. H.; von Helden, G.; Pagel, K.: Fucose migration in intact protonated glycan ions: a universal phenomenon in mass spectrometry. Angewandte Chemie International Edition 57 (25), pp. 7440 - 7443 (2018)
Journal Article
Mucha, E.; Marianski, M.; Xu, F.-F.; Thomas, D. A.; Meijer, G.; von Helden, G.; Seeberger, P. H.; Pagel, K.: Unravelling the structure of glycosyl cations via cold-ion infrared spectroscopy. Nature Communications 9, 4174 (2018)
Journal Article
Ng, S.; Bennett, N. J.; Schulze, J.; Gao, N.; Rademacher, C.; Derda, R.: Genetically-encoded fragment-based discovery of glycopeptide ligands for DC-SIGN. Bioorganic & Medicinal Chemistry 26 (19), pp. 5368 - 5377 (2018)
Journal Article
Ota, F.; Hirayama, T.; Kizuka, Y.; Yamaguchi, Y.; Fujinawa, R.; Nagata, M.; Ismanto, H. S.; Lepenies, B.; Aretz, J.; Rademacher, C. et al.; Seeberger, P. H.; Angata, T.; Kitazume, S.; Yoshida, K.; Betsuyaku, T.; Kida, K.; Yamasaki, S.; Taniguchi, N.: High affinity sugar ligands of C-type lectin receptor langerin. Biochimica et Biophysica Acta (BBA) - General Subjects 1862 (7), pp. 1592 - 1601 (2018)
Journal Article
Pardo-Vargas, A.; Delbianco, M.; Seeberger, P. H.: Automated glycan assembly as an enabling technology. Current Opinion in Chemical Biology 46, pp. 48 - 55 (2018)
Journal Article
Pieber, B.; Shalom, M.; Antonietti, M.; Seeberger, P. H.; Gilmore, K.: Continuous heterogeneous photocatalysis in serial micro-batch reactors. Angewandte Chemie International Edition 57 (31), pp. 9976 - 9979 (2018)
Journal Article
Qin, C.; Schumann, B.; Zou, X.; Pereira, C. L.; Tian, G.; Hu, J.; Seeberger, P. H.; Yin, J.: Total synthesis of a densely functionalized Plesiomonas shigelloides serotype 51 aminoglycoside trisaccharide antigen. Journal of the American Chemical Society 140 (8), pp. 3120 - 3127 (2018)
Journal Article
Rath, C. B.; Schirmeister, F.; Figl, R.; Seeberger, P. H.; Schaeffer, C.; Kolarich, D.: Flagellin glycoproteomics of the periodontitis associated pathogen Selenomonas sputigena reveals previously not described O-glycans and rhamnose fragment rearrangement occurring on the glycopeptides. Molecular and Cellular Proteomics 17 (4), pp. 721 - 736 (2018)
Journal Article
Riggs, D. L.; Hofmann, J.; Hahm, H. S.; Seeberger, P. H.; Pagel, K.; Julian, R. R.: Glycan isomer identification using ultraviolet photodissociation initiated radical chemistry. Analytical Chemistry 90 (19), pp. 11581 - 11588 (2018)
Journal Article
Rong, J.; Seeberger, P. H.; Gilmore, K.: Chemoselective photoredox synthesis of unprotected primary amines using ammonia. Organic Letters 20 (13), pp. 4081 - 4085 (2018)
Journal Article
Ruprecht, C.; Dallabernardina, P.; Smith, P. J.; Urbanowicz, B. R.; Pfrengle, F.: Analyzing xyloglucan endotransglycosylases by incorporation of synthetic oligosaccharides into plant cell walls. ChemBioChem: A European Journal of Chemical Biology 19 (8), pp. 793 - 798 (2018)
Journal Article
Schulze, J.; Baukmann, H.; Wawrzinek, R.; Fuchsberger, F. F.; Specker, E.; Aretz, J.; Nazaré, M.; Rademacher, C.: CellFy: a cell-based fragment screen against C-type lectins. ACS Chemical Biology 13 (12), pp. 3229 - 3235 (2018)
Journal Article
Schumann, B.; Reppe, K.; Kaplonek, P.; Wahlbrink, A.; Chakkumkal, A.; Witzenrath, M.; Pereira, C. L.; Seeberger, P. H.: Development of an efficacious, semisynthetic glycoconjugate vaccine candidate against Streptococcus pneumoniae serotype 1. ACS Central Science 4 (3), pp. 357 - 361 (2018)
Journal Article
Senf, D.; Ruprecht, C.; Kishani, S.; Matic, A.; Toriz, G.; Gatenholm, P.; Wågberg, L.; Pfrengle, F.: Tailormade polysaccharides with defined branching patterns: enzymatic polymerization of arabinoxylan oligosaccharides. Angewandte Chemie International Edition 57 (37), pp. 11987 - 11992 (2018)
Journal Article
Senf, D.; Ruprecht, C.; Kishani, S.; Matic, A.; Toriz, G.; Gatenholm, P.; Wågberg, L.; Pfrengle, F.: Tailor-made polysaccharides with defined branching patterns by enzymatic polymerization of arabinoxylan oligosaccharides. Angewandte Chemie, International Edition in English 57 (37), pp. 11987 - 11992 (2018)
Journal Article
Sommer, R.; Wagner, S.; Rox, K.; Varrot, A.; Hauck, D.; Wamhoff, E.-C.; Schreiber, J.; Ryckmans, T.; Brunner, T.; Rademacher, C. et al.; Hartmann, R. W.; Brönstrup, M.; Imberty, A.; Titz, A.: Glycomimetic, orally bioavailable LecB inhibitors block biofilm formation of Pseudomonas aeruginosa. Journal of the American Chemical Society 140 (7), pp. 2537 - 2545 (2018)
Journal Article
Tian, G.-Z.; Hu, J.; Zhang, H.-X.; Rademacher, C.; Zou, X.-P.; Zheng, H.-N.; Xu, F.; Wang, X.-L.; Yin, T. L. &. J.: Synthesis and conformational analysis of linear homo- and heterooligomers from novel 2-C-branched sugar amino acids (SAAs). Scientific Reports 8, 6625 (2018)
Journal Article
Triemer, S.; Gilmore, K.; Vu, G. T.; Seeberger, P. H.; Seidel-Morgenstern, A.: Literally green chemical synthesis of artemisinin from plant extracts. Angewandte Chemie International Edition 57 (19), pp. 5525 - 5528 (2018)
Journal Article
Viana, H.; Marques, C. S.; Correia, C. A.; Gilmore, K.; Galvão, L.; Vieira, L.; Seeberger, P. H.; Burke, A. J.: Novel palladium-catalyzed intramolecular addition of aryl bromides to aldehydes as key to the synthesis of 3,3-dimethylchroman-4-ones and 3,3-dimethylchroman-4-ols. ChemistrySelect 3 (40), pp. 11333 - 11338 (2018)
Journal Article
Warias, R.; Zaghi, A.; Heiland, J. J.; Piendl, S. K.; Gilmore, K.; Seeberger, P. H.; Massi, A.; Belder, D.: An integrated lab-on-a-chip approach to study heterogeneous enantioselective catalysts at the microscale. ChemCatChem 10 (23), pp. 5382 - 5385 (2018)
Journal Article
Ye, Z.; Wu, W.; Qin, Y.; Hu, J.; Liu, C.; Seeberger, P. H.; Yin, J.: An integrated therapeutic delivery system for enhanced treatment of hepatocellular carcinoma. Advanced Functional Materials 28 (18), 1706600 (2018)
Journal Article
Yu, Y.; Kononov, A.; Delbianco, M.; Seeberger, P. H.: A capping step during automated glycan assembly enables access to complex glycans in high yield. Chemistry – A European Journal 24 (23), pp. 6075 - 6078 (2018)
Journal Article
Zou, X.; Qin, C.; Pereira, C. L.; Tian, G.; Hu, J.; Seeberger, P. H.; Yin, J.: Synergistic glycosylation as key to the chemical synthesis of an outer core octasaccharide of Helicobacter pylori. Chemistry – A European Journal 24 (12), pp. 2868 - 2872 (2018)

Book Chapter (3)

2018
Book Chapter
Ch’ng, A. C. W.; Hamidon, N. H. B.; Konthur, Z.; Lim, T. S.: Magnetic nanoparticle-based semi-automated panning for high-throughput antibody selection. In: Methods in Molecular Biology, Vol. 1701, pp. 301 - 319 (2018)
Book Chapter
Moon, S.-Y.; Gilmore, K.; Seeberger, P. H.: The controlled synthesis of carbohydrates. In: Science of synthesis: flow chemistry in organic systems, pp. 399 - 428 (Eds. Jamison, T.; Koch, G.). Georg Thieme Verlag KG, Stuttgart (2018)
Book Chapter
Pfrengle, F.; Seeberger, P. H.: Orthogonally protected building blocks for automated glycan assembly. In: Protecting Groups, pp. 451 - 471. Wiley-VCH, Weinheim (2018)

Meeting Abstract (1)

2018
Meeting Abstract
Nycholat, C. M.; Duan, S.; Willis, S.; Wamhoff, E.-C.; Arthur, C.; McBride, R.; Rademacher, C.; Stowell, S.; Paulson, J. C.: Synthetic glycan analog libraries for the development of selective, high affinity ligands of siglecs and galectins. In Glycobiology, 28 (12), 185, pp. 1075 - 1076. Annual Meeting of the Society for Glycobiology, New Orleans, LA, November 05, 2018 - November 08, 2018. Oxford University Press, Oxford (2018)

Poster (1)

2018
Poster
Hofmann, K.; Reppe, K.; Parameswarappa, S.; Pereira, C.; Nouailles, G.; Bonin, A. v.; Klopfleisch, R.; Seeberger, P. H.; Witzenrath, M.: Eine semi-synthetische S. pneumoniae Serotyp 3 Tetrasaccharid-Konjugatvakzine schützt Mäuse vor Pneumonie. (2018)

Thesis - PhD (7)

2018
Thesis - PhD
Bartetzko, M. P.: Development of synthetic glycan tools for investigating plant cell wall pectins. Dissertation, 199 pp., Freie Universität Berlin, Berlin (2018)
Thesis - PhD
Kononov, A.: Oligosaccharides prepared by automated glycan assembly as basis for structural investigations of carbohydrates. Dissertation, 167 pp., Freie Universität, Berlin (2018)
Thesis - PhD
Roller, R.: Intein-mediated semi-synthesis and characterization of glycosylphosphatidylinositol (GPI)-anchord proteins. Dissertation, Freie Universität Berlin, Berlin (2018)
Thesis - PhD
Schulze, J.: Towards Langerhans cell immune modulation: From ligand identification to antigen delivery and what we can learn from nature. Dissertation, 194 pp., Freie Universität, Berlin (2018)
Thesis - PhD
Senf, D.: Synthesis of arabinoxylan oligo- and polysaccharides from the plant cell wall. Dissertation, 165 pp., Freie Universität Berlin, Berlin (2018)
Thesis - PhD
Varela-Aramburu, S.: Carbohydrate-based nanomaterials for imaging and drug delivery. Dissertation, 161 pp., Freie Universität, Berlin (2018)
Thesis - PhD
Xu, F.-F.: Synthetic oligosaccharides as tools to investigate bacterial capsular polysaccharides and teichoic acids. Dissertation, 191 pp., Freie Universität, Berlin (2018)

Thesis - Master (1)

2018
Thesis - Master
Fortes, R.: Synthesis of Carbohydrate Building Blocks for Automated Glycan Assembly. Master, 67 pp., Freie Universität Berlin, Berlin (2018)

Patent (2)

2018
Patent
Seeberger, P. H.: Pneumococcal polysaccharide-protein conjugate composition. WO2017220753 (2018)
Patent
Seeberger, P. H.: Stable hydrolysis-resistant synthetic Polyribosylribitolphosphate derivates as vaccines against Haemophilus influenzae type b. (2018)
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